Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Chronic arthritis |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic tophaceous gout (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic articular rheumatism |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic bursitis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic pseudo-obstruction of small intestine |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic perichondritis of pinna |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Recurrent dislocation of joint |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Non-traumatic acute-on-chronic slipped upper femoral epiphysis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic osteomyelitis of knee (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic osteomyelitis of hip (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic crepitant synovitis of wrist |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Recurrent dislocation of temporomandibular joint (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic perichondritis of pinna |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Recurrent dislocation of ankle AND/OR foot |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic instability of knee |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Recurrent dislocation of joint |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic osteoarthritis |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare autoinflammatory syndrome with characteristics of the presence of features of relapsing polychondritis and Behcet disease in the same individual. This includes cartilage inflammation of the ears, nose, throat and rib cage as well as recurrent oral and genital ulcers respectively. Patients may also present ocular involvement (in particular anterior uveitis or scleritis), arthritis, fever, colitis, thrombophlebitis, and central nervous system vasculitis or in rare cases arterial aneurysms. Symptoms of polychondritis occur secondary to those of Behcet disease in the vast majority of cases. |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Jaccoud's syndrome |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic instability of ankle syndesmosis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of wrist (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of vertebra (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of shoulder (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of ankle and/or foot (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of hand (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of knee (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of elbow (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Primary chronic gout without tophus of hip (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of vertebra without tophus due to renal impairment (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of wrist without tophus due to renal impairment |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of ankle without tophus due to renal impairment |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of shoulder without tophus due to renal impairment (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of elbow without tophus due to renal impairment (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of hip without tophus due to renal impairment (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of knee without tophus due to renal impairment |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of hand without tophus due to renal impairment (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of wrist without tophus caused by drug |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of vertebra without tophus caused by drug |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of elbow without tophus caused by drug (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of knee without tophus caused by drug (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of shoulder without tophus caused by drug |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of hand without tophus caused by drug (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of hip without tophus caused by drug (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gout of ankle and/or foot without tophus caused by drug |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Intermittent effusion of joint (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of medial collateral ligament of right knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of anterior cruciate ligament of right knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of posterior cruciate ligament of right knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of medial collateral ligament of left knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of anterior cruciate ligament of left knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of posterior cruciate ligament of left knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Intermittent locking of temporomandibular joint (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic arthralgia of temporomandibular joint (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic derangement of meniscus of bilateral knees |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of lateral collateral ligament of right knee |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of lateral collateral ligament of left knee (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Non-traumatic chronic slipped upper femoral epiphysis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Recessive intellectual disability-motor dysfunction-multiple joint contractures syndrome is a rare, genetic, syndromic intellectual disability disorder characterized by severe intellectual disability, progressive, postnatal, multiple joint contractures and severe motor dysfunction. Patients present arrest and regression of motor function and speech acquisition, as well as contractures which begin in lower limbs and slowly progress in an ascending manner to include spine and neck, resulting in individuals presenting a specific fixed position. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare genetic skin disorder characterized by very early-onset of progressive skin thickening over the entire body (except for eyelids, neck and ears), progressively limited joint mobility with gradual freezing of joints, and eventual severe chest and abdomen movement restriction, manifesting with restrictive pulmonary disease, which may lead to death. Additional features include severe growth restriction and osteoporosis. There have been no further descriptions in the literature since 1974. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Madelung's deformity (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Multiple epiphyseal dysplasia, with severe proximal femoral dysplasia is a rare primary bone dysplasia characterized by severe, early-onset dysplasia of the proximal femurs, with almost complete absence of the secondary ossification centers and abnormal development of the femoral necks (short and broad with irregular metaphyses). It is associated with gait abnormality, mild short stature, arthralgia, joint stiffness with limited mobility of the hips and irregular acetabula, and hip and knee pain. Coxa vara and mild spinal changes are also associated. |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Multiple dislocations with dysplasia |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
A primary bone dysplasia, characterized by premature degenerative arthropathy of the hip. The disease presents with hip joint discomfort/pain and gait disturbances that usually develop in childhood and that progress to severe functional disability and limited mobility by early adulthood. Involvement of the vertebral bodies and other joints is minimal, height is not significantly reduced, and general health is unimpaired. Radiographically, the femoral heads are flattened and irregular and degenerative osteoarthritis develops in the hip joints, as evidenced by the presence of periarticular cysts, sclerosis, and joint space narrowing. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Palindromic rheumatism |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic tophaceous gout of shoulder caused by drug (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Derangement of meniscus of knee joint due to and following old injury of knee (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Old complete tear medial collateral ligament |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic infantile neurological, cutaneous and articular syndrome |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Old disruption of ligament of knee (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Derangement of knee |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Old tear of posterior horn of medial meniscus |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Monoarticular chronic primary gouty arthritis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rheumatoid nodular fibrosis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare genetic immune disease characterized by early onset of recurrent bacterial, viral, and fungal infections, chronic inflammatory bowel disease, gastritis, and inflammatory polyarthritis. Patients present with diarrhea, vomiting, hepatosplenomegaly, mouth ulcers, perianal abscesses, chronic lung disease with bronchiectasis, and failure to thrive. Occurrence of a skin rash associated with lymphocytic vasculitis has also been reported. Immunologic abnormalities include variable T-cell lymphopenia, decreased natural killer cells, and decreased B-cells with variable hypogammaglobulinemia. |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare temporomandibular joint anomaly characterized by progressive, asymmetrical, non-neoplastic overgrowth of a mandibular condyle. It is unilateral in most cases and leads to progressive facial asymmetry, mandibular deviation, articular dysfunction, and dental malocclusion. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Persistent prosthetic joint pain |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic joint effusion |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Remitting seronegative symmetrical synovitis with pitting edema (disorder) |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare primary bone dysplasia with multiple joint dislocations characterized by stunted stature, articular hypermobility and spinal malalignment resulting in severe progressive kyphosis. Joint dislocations include bilateral dislocation of the radial heads with elbow contractures, feet (bilateral talipes equinovarus) and congenital dislocations of the hip and genu valgus. Joint laxity is particularly observed in fingers. Spinal changes include moderate platyspondyly with anterior projection of the vertebral bodies. Facial features of oval face with a flattened nasal bridge, button nose, long upper lip, prominent eyes and blue sclera are characteristic but variable. Patients may also present mild skin extensibility, spatulate terminal phalanges, lip and palate clefts, micrognathia and structural cardiac malformations. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare primary bone dysplasia characterized by multiple joint dislocations, in particular in hips and knees present at birth, but the elbows, wrists, ankles, and patellae can also be affected; severe joint laxity, scoliosis, slender fingers with distal tapering, and growth deficiency developing in the post-natal period resulting in short stature. Gracile metacarpals and metatarsals, delayed bone age with poorly ossified carpal and tarsal bones, metaphyseal and epiphyseal dysplasia, slender ribs, and spondylar dysplasia are radiographical signs. Intelligence is usually normal. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic rupture of lateral collateral ligament of knee joint (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
PAPASH syndrome |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare autoinflammatory syndrome with characteristics of a chronic-relapsing course of the combination of pyoderma gangrenosum, acne, hidradenitis suppurativa (which, in addition to axillae and inguinal folds, can be observed on upper and lower limbs, back, and buttocks, among others), and ankylosing spondylitis. Typical age of onset is adolescence to young adulthood, with the different signs and symptoms appearing simultaneously or subsequently. |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic derangement of anterior horn of lateral meniscus |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic derangement of posterior horn of medial meniscus (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic derangement of posterior horn of lateral meniscus (disorder) |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Relapsing polychondritis |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Polyarticular chronic gout caused by lead |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
Degeneration of lateral meniscus |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Monoarticular chronic gout caused by lead |
Is a |
False |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare spondyloepiphyseal dysplasia characterized by progressive joint contractures with premature degenerative joint disease, particularly in the knee, hip, and finger joints. Patients are of normal height and present with gait problems, joint pain, and enlarged joints with joint restriction and contractures. Radiological features include generalized platyspondyly, hypoplastic ilia, epiphyseal flattening with metaphyseal splaying of the tubular bones, and broad, elongated femoral necks with marked coxa valga. Histopathologic examination of cartilage shows PAS-positive cytoplasmic inclusion bodies in chondrocytes. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
dystrophie musculaire congénitale associée à une arthrogrypose congénitale multiple |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Autosomal recessive myogenic arthrogryposis multiplex congenita is a rare inherited neuromuscular disease characterized by prenatal presentation (usually in the second trimester) of reduced fetal movements and abnormal positioning resulting in joint abnormalities that may involve both lower and upper extremities and is usually symmetric, severe hypotonia at birth with bilateral club foot, motor development delay, mild facial weakness without ophthalmoplegia, absent deep tendon reflexes, normal motor and sensory nerve conduction velocities, no cerebellar or pyramidal involvement, and progressive disease course with loss of ambulation after the first decade of life. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
A rare form of spinal muscular atrophy characterized by the neonatal onset of severe hypotonia, areflexia, profound weakness, multiple congenital contractures, facial dysmorphic features (myopathic face with open, tent-shaped mouth), cryptorchidism, and mild skeletal abnormalities (i.e. kyphosis, scoliosis), that is often preceded by polyhydramnios and reduced fetal movements in utero and followed by bone fractures shortly after birth. Muscle weakness is progressive and chest muscle involvement eventually leads to ventilatory insufficiency and respiratory failure. |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|
Chronic gouty arthritis |
Is a |
True |
Chronic arthropathy |
Inferred relationship |
Some |
|