395829001: Estropipate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Sex hormone (substance)\Substance with estrogen receptor agonist mechanism of action (substance)\Estropipate
\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\Steroid hormone\Estropipate
\Substance categorized by disposition\Receptor agonist\Substance with estrogen receptor agonist mechanism of action (substance)\Estropipate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Polycyclic compound (substance)\Steroid\...

\Corticosteroid and/or corticosteroid derivative\17-ketosteroid (substance)\Estropipate

\Estrane\Estrone and/or estrone derivative\Estropipate

\Steroid hormone\Estropipate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

1477359019 Piperazine estrone sulfate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

2476993017 Estropipate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3672148017 Estropipate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

810001000172113 sulfate de pipérazine estrone fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Estropipate	Is a	pipérazine	false	Inferred relationship	Some
Estropipate	Is a	Estrone	false	Inferred relationship	Some
Estropipate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Estrogen	false	Inferred relationship	Some
Estropipate	Is a	Estradiol and/or estradiol derivative	false	Inferred relationship	Some
Estropipate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Estrone	false	Inferred relationship	Some
Estropipate	Is a	Estrane	false	Inferred relationship	Some
Estropipate	Is a	estrogeno	false	Inferred relationship	Some
Estropipate	Is a	17-ketosteroid (substance)	true	Inferred relationship	Some
Estropipate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Gonadal hormone	false	Inferred relationship	Some
Estropipate	Is a	Substance with estrogen receptor agonist mechanism of action (substance)	true	Inferred relationship	Some
Estropipate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Estrogen receptor agonist	true	Inferred relationship	Some
Estropipate	Is a	Steroid hormone	true	Inferred relationship	Some
Estropipate	Is a	Estrone and/or estrone derivative	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Estropipate 1.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Piperazine estrone sulfate adverse reaction	Causative agent (attribute)	True	Estropipate	Inferred relationship	Some	1
Product containing piperazine estrone sulfate	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 1.25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Product containing precisely estropipate 625 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 750 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 3 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 2.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 1.5mg tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Estropipate 1.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Product containing estropipate in oral dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Product containing estropipate in vaginal dosage form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
Product containing precisely estropipate 1.5 milligram/1 milliliter conventional release vaginal cream (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some
allergie au sulfate de pipérazine estrone	Causative agent (attribute)	False	Estropipate	Inferred relationship	Some	2
Estropipate 1.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Estropipate 1.5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Product containing precisely estropipate 625 microgram/1 each conventional release oral tablet (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Product containing precisely estropipate 625 microgram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Estropipate 1.25 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Estropipate 1.25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Estropipate 2.5 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Estropipate 2.5 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Estropipate 3 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Estropipate 3 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Estropipate 750 microgram oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Estropipate	Inferred relationship	Some	1
Estropipate 750 microgram oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Estropipate 750 microgram oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Product containing precisely estropipate 625 microgram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Estropipate 2.5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Estropipate 1.25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Estropipate 3 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Estropipate 1.5 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Allergy to estropipate	Causative agent (attribute)	False	Estropipate	Inferred relationship	Some	1
Product containing precisely estropipate 1.5 milligram/1 milliliter conventional release vaginal cream (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Estropipate	Inferred relationship	Some	1
Product containing precisely estropipate 1.5 milligram/1 milliliter conventional release vaginal cream (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Estropipate	Inferred relationship	Some	1
Estropipate only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1
Product containing estropipate in vaginal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1
Product containing only estropipate in vaginal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1
Estropipate-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1
Estropipate only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1
Estropipate-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Estropipate	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
1477359019	Piperazine estrone sulfate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2476993017	Estropipate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3672148017	Estropipate (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
810001000172113	sulfate de pipérazine estrone	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module