395939008: Clavulanic acid (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Substance with beta-lactamase inhibitor mechanism of action\Clavulanic acid (substance)
\Substance categorized by disposition\Antibacterial\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Anti-infective agent (substance)\Antibacterial\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Beta-lactam (substance)\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Lactam\Beta-lactam (substance)\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)
\Organic compound\Organic cyclic compound\Heterocyclic compound\Azetidine derivative (substance)\Beta-lactam (substance)\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)
\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Amide\Lactam\Beta-lactam (substance)\Substance with beta-lactam structure and antibacterial mechanism of action (substance)\Clavulanic acid (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2003. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Clavulanic acid (substance)	Is a	Substance with beta-lactam structure and antibacterial mechanism of action (substance)	true	Inferred relationship	Some
Clavulanic acid (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Beta-lactamase inhibitor	true	Inferred relationship	Some
Clavulanic acid (substance)	Is a	Substance with beta-lactamase inhibitor mechanism of action	true	Inferred relationship	Some
Clavulanic acid (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Antibacterial (disposition)	true	Inferred relationship	Some
Clavulanic acid (substance)	Is a	Beta-lactam (substance)	false	Inferred relationship	Some
Clavulanic acid (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Clavulanate	Is a	False	Clavulanic acid (substance)	Inferred relationship	Some
Clavulanate potassium (substance)	Is a	False	Clavulanic acid (substance)	Inferred relationship	Some
Product containing clavulanic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely clavulanic acid (as clavulanate potassium) 200 milligram and ticarcillin (as ticarcillin disodium) 3 gram/1 vial powder for conventional release solution for injection (clinical drug)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clavulanic acid (substance)	Inferred relationship	Some
Product containing clavulanic acid and ticarcillin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Ticarcillin 3g/clavulanic acid 100mg powder for injection solution vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clavulanic acid (substance)	Inferred relationship	Some
Ticarcillin+clavulanic acid 3g/0.1g infusion 100mL bag	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Clavulanic acid (substance)	Inferred relationship	Some
Ticarcillin and clavulanic acid adverse reaction	Causative agent (attribute)	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Allergy to ticarcillin and clavulanic acid	Causative agent (attribute)	False	Clavulanic acid (substance)	Inferred relationship	Some
Amoxicillin and clavulanate	Is a	False	Clavulanic acid (substance)	Inferred relationship	Some
Amoxicillin 250 mg and clavulanic acid (as clavulanate potassium) 125 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 875 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 500 mg and clavulanic acid (as clavulanate potassium) 125 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Amoxicillin 250 mg and clavulanic acid (as clavulanate potassium) 125 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin 875 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing amoxicillin and clavulanic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Clavulanate potassium (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Clavulanic acid (substance)	Inferred relationship	Some
Amoxicillin and clavulanate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Clavulanic acid (substance)	Inferred relationship	Some
Product containing precisely amoxicillin (as amoxicillin sodium) 500 milligram and clavulanic acid (as clavulanate potassium) 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Amoxicillin (as amoxicillin sodium) 1 g and clavulanic acid (as clavulanate potassium) 200 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin trihydrate) 50 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 12.5 milligram/1 milliliter conventional release oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin trihydrate) 25 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 6.25 milligram/1 milliliter conventional release oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely clavulanic acid (as clavulanate potassium) 200 milligram and ticarcillin (as ticarcillin disodium) 3 gram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin trihydrate) 80 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 11.4 milligram/1 milliliter conventional release oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing amoxicillin and clavulanic acid in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing amoxicillin and clavulanic acid in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Clavulanic acid- and ticarcillin-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing only clavulanic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing only clavulanic acid and ticarcillin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing only amoxicillin and clavulanic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Clavulanic acid and ticarcillin only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin and clavulanic acid only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing only amoxicillin and clavulanic acid in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Allergy to ticarcillin and clavulanic acid	Causative agent (attribute)	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin (as amoxicillin trihydrate) 500 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 125 mg and clavulanic acid (as clavulanate potassium) 31.2 mg chewable tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin anhydrous (as amoxicillin) 200 milligram and clavulanic acid (as clavulanate potassium) 28.5 milligram/1 each conventional release chewable tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely clavulanic acid (as clavulanate potassium) 1 milligram and ticarcillin (as ticarcillin disodium) 30 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin anhydrous (as amoxicillin) 120 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 8.58 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin anhydrous (as amoxicillin) 250 milligram and clavulanic acid (as clavulanate potassium) 62.5 milligram/1 each conventional release chewable tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin anhydrous (as amoxicillin) 400 milligram and clavulanic acid (as clavulanate potassium) 57 milligram/1 each conventional release chewable tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin anhydrous (as amoxicillin) 40 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 5.7 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	1
Product containing precisely amoxicillin (as amoxicillin trihydrate) 250 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin trihydrate) 875 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 25 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 6.25 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 500 mg and clavulanic acid (as clavulanate potassium) 125 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 80 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 11.4 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 50 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 12.5 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin sodium) 500 milligram and clavulanic acid (as clavulanate potassium) 100 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely clavulanic acid (as clavulanate potassium) 100 milligram and ticarcillin (as ticarcillin disodium) 3 gram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 400 mg and clavulanic acid (as clavulanate potassium) 57 mg chewable tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 200 milligram and clavulanic acid (as clavulanate potassium) 28.5 milligram/1 each conventional release chewable tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 250 mg and clavulanic acid (as clavulanate potassium) 62.5 mg chewable tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 40 milligram/1 milliliter and clavulanic acid (as clavulanate potassium) 5.7 milligram/1 milliliter conventional release oral suspension (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin 120 mg/mL and clavulanic acid (as clavulanate potassium) 8.58 mg/mL oral suspension	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin (as amoxicillin sodium) 250 mg and clavulanic acid (as clavulanate potassium) 50 mg powder for solution for injection vial	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing cefuroxime and clavulanic acid (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Cefuroxime and clavulanic acid only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing cefuroxime and clavulanic acid in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing only cefuroxime and clavulanic acid in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely cefuroxime (as cefuroxime axetil) 500 milligram and clavulanic acid (as clavulanate potassium) 125 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 200 milligram and clavulanic acid (as clavulanate potassium) 28.5 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin 400 milligram and clavulanic acid (as clavulanate potassium) 57 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin sodium) 500 milligram and clavulanic acid (as clavulanate potassium) 50 milligram/1 vial powder for conventional release solution for infusion and/or injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin sodium) 500 milligram and clavulanic acid (as clavulanate potassium) 50 milligram/1 vial powder for conventional release solution for infusion (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Product containing precisely amoxicillin (as amoxicillin sodium) 500 milligram and clavulanic acid (as clavulanate potassium) 50 milligram/1 vial powder for conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Clavulanic acid (substance)	Inferred relationship	Some	2
Amoxicillin and clavulanic acid therapy	Direct substance	True	Clavulanic acid (substance)	Inferred relationship	Some	2

Reference Sets

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Id	Description	Lang	Type	Status	Case?	Module
1469879013	Clavulanic acid (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1489571011	Clavulanic acid	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2476996013	Clavulanate	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
57561000195118	acido clavulanico	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
801261000172111	acide clavulanique	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
73231000195118	Clavulansäure	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module