| Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
| Stilboestrol adverse reaction |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Allergy to diethylstilbestrol (finding) |
Causative agent (attribute) |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Stilbestrol [gynecological use] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Stilbestrol+lactic acid 500micrograms/5% pessary |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Stilbestrol [malignancy] |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Diethylstilbestrol 1 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Diethylstilbestrol diphosphate preparation |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Diethylstilbestrol poisoning |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Product containing diethylstilbestrol (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Product containing diethylstilbestrol and lactic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol measurement |
Component |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Allergy to diethylstilbestrol (finding) |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Exposure to diethylstilbestrol |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| A malformation syndrome reported in offspring (children and grandchildren) of women exposed to diethylstilbestrol (DES) during pregnancy and is characterised by reproductive tract malformations, decreased fertility and increased risk of developing clear cell carcinoma of the vagina and cervix in young women. Reproductive malformations reported in DES syndrome include small, T-shaped uteri and other uterotubal anomalies that increase the risk of miscarriages in women and epididymal cysts, microphallus, cryptorchidism, or testicular hypoplasia in men. DES, a synthetic nonsteroidal estrogen was widely prescribed from 1940-1970 to prevent miscarriage. |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol 1 mg oral tablet |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol 1 mg oral tablet |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Exposure to diethylstilbestrol in utero (event) |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Fosfestrol tetrasodium (substance) |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
False |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Product containing precisely diethylstilbestrol 5 milligram/1 each conventional release oral tablet (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol 1 mg oral tablet |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol-containing product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Product containing only diethylstilbestrol and lactic acid (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol only product in oral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Fosfestrol (substance) |
This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
|
| Product containing only diethylstilbestrol in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Diethylstilbestrol-containing product in parenteral dose form |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| 46,XX disorder of sex development caused by synthetic oral diethylstilbestrol |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Neonatal disorder caused by diethylstilbestrol transmitted via breast milk (disorder) |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
| Fetal disorder caused by diethylstilbestrol transmitted via placenta |
Causative agent (attribute) |
True |
Diethylstilbestrol (substance) |
Inferred relationship |
Some |
1 |
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