Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Hypermelanosis of undetermined etiology (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to ACTH/MSH-secreting tumour |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to hormonal factor (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to cryotherapy (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to neoplasia (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Buccal pigmentation due to Addison's disease (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Hypermelanosis due to connective tissue disorder (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Deep penetrating melanocytic nevus (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to nervous system disorder (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis caused by photodynamic agent (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Hypermelanosis due to acromegaly (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Combined melanocytic nevus (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Circumscribed acquired hypermelanosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Eruptive melanocytic nevi (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Multiple benign melanocytic nevi (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis of the eyelids due to hyperthyroidism (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Multiple atypical melanocytic nevi (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Poikiloderma caused by photodynamic agent (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
4 |
Lupus erythematosus-associated hypermelanosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to malignant ACTH/MSH-secreting tumour |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to pheochromocytoma (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to phytophotodermatitis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Metastatic malignant melanoma with diffuse hypermelanosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to Cushing syndrome (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to hyperthyroidism (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypermelanosis due to endocrine disorder (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Palmar pitting due to Darier disease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Acquired plantar keratoderma (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
4 |
Acquired keratoderma (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
4 |
Acquired disorder of keratinization (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Hereditary benign acanthosis nigricans with insulin resistance |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
A rare, genetic, developmental defect during embryogenesis syndrome characterized by generalized keratosis follicularis, severe proportionate dwarfism and cerebral atrophy. Alopecia (of scalp, eyebrows and eyelashes) and microcephaly are additionally observed features. Intellectual disability, inguinal hernia and epilepsy may also be associated. There have been no further descriptions in the literature since 1974. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Acquired keratosis follicularis |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Relapsing linear acantholytic dermatosis (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Acrokeratosis paraneoplastica of Bazex |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
4 |
Darier disease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Acquired acantholytic dermatosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Acquired palmoplantar keratoderma (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
4 |
A rare, X-linked syndromic intellectual disability disorder characterized by severe intellectual disability, psychomotor developmental delay, generalized seizures, and psoriasis. Mild craniofacial dysmorphism, such as hypertelorism, broad nasal bridge, anteverted nares, macrostomia, highly arched palate and large ears, is also associated. There have been no further descriptions in the literature since 1988. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
kératodermie acquise palmaire et plantaire |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Focal acral hyperkeratosis (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Dry skin dermatitis |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Acquired keratosis pilaris |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Acrokeratosis verruciformis of Darier disease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Flexural Darier's disease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Linear/nevoid/zosteriform Darier's disease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Virus-associated trichodysplasia spinulosa is a rare infectious skin disease characterized by the development of follicular papules with keratin spicules in various parts of the body, predominantly in the face (e.g. nose, eyebrows, auricles), that is due to polyomavirus infection in immunocompromized patients. |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Perinatal skin trauma due to obstetric injury (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Pilonidal cyst |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
|
kyste pilonidal abcédé |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
|
Sebaceous cyst of skin |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Ulcer of skin caused by polycyclic aromatic hydrocarbons |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hypotrichosis with keratosis pilaris and lentiginosis |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
A rare association syndrome, reported in several members of two families to date, characterized by arterial dissection, occurring at an early age and presenting with a range of manifestations depending on the vascular territory involved (headache, dysphasia, hemiparesis), in association with cystic medial necrosis and multiple lentigines (brown and black in color and mainly affecting the skin of the trunk and extremities). |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Peutz-Jeghers syndrome |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Neuropathic ulcer of ankle (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Neuropathic ulcer of midfoot AND/OR heel due to type 2 diabetes mellitus |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Skin damage resulting from acquired nerve disorder (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Neuropathic ulcer (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Neurotrophic damage to skin (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Trigeminal trophic syndrome (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Lyell syndrome due to infection (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Lyell syndrome due to infection (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Lyell syndrome due to infection (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
An extended form of toxic epidermal necrolysis with characteristics of destruction and detachment of the skin epithelium and mucous membranes involving more than 30% of the body surface area. Lyell syndrome can be triggered by a drug allergy and, exceptionally, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear. Patients should be admitted to an intensive care or burns unit as soon as the diagnosis is suspected. Prognosis is poor (mortality rate: 20-25%). |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
An extended form of toxic epidermal necrolysis with characteristics of destruction and detachment of the skin epithelium and mucous membranes involving more than 30% of the body surface area. Lyell syndrome can be triggered by a drug allergy and, exceptionally, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear. Patients should be admitted to an intensive care or burns unit as soon as the diagnosis is suspected. Prognosis is poor (mortality rate: 20-25%). |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Peripheral demyelinating neuropathy-central dysmyelinating leucodystrophy-Waardenburg syndrome-Hirschsprung disease (PCWH) is a systemic disease characterised by the association of the features of Waardenburg-Shah syndrome (WSS) with neurological features of variable severity. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Secondary non-thrombocytopenic purpura |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Purpura due to prolonged vomiting and/or coughing (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Chronic idiopathic thrombocytopenic purpura (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Neonatal purpura fulminans due to homozygous protein C deficiency (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Contact purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Mechanical purpura |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
purpura thrombopénique aigu idiopathique |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |
Upshaw-Schulman syndrome (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
5 |
Cryofibrinogenemic purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Autoimmune thrombotic thrombocytopenic purpura (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
5 |
Purpura fulminans |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Drug induced thrombotic thrombocytopenic purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
Eczematid-like purpura of Doucas and Kapetanakis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Waldenstrom's hypergammaglobulinaemic purpura |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Vascular hemostatic disease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Itching purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Postinfective immunoglobulin A vasculitis (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Clothing purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Purpura due to increased intravascular pressure (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Thrombocytopenic purpura due to defective platelet production (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Thrombocytopenic purpura due to platelet consumption (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Secondary cutaneous vasculitis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hyperglobulinemic purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Post infectious thrombocytopenic purpura |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Dysproteinemic purpura (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Acute haemorrhagic oedema of childhood |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Capillary fragility abnormality |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
purpura thrombopénique congénital |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
Thrombocytopenic purpura |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. It may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of the disorder that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic purpura fulminans. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Purpura pigmentosa chronica |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
purpura thrombopénique idiopathique |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
3 |