Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Reconstruction of skin using local subcutaneous pedicle V-Y random pattern skin flap (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Reconstruction of skin using local subcutaneous pedicle random pattern skin flap |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Neurofibromatosis type 6 (NF6), also referred as café-au-lait spots syndrome, is a cutaneous disorder characterized by the presence of several café-au-lait (CAL) macules without any other manifestations of neurofibromatosis or any other systemic disorder. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare, acquired, dermis elastic tissue disorder with decreased elastic tissue characterized by multiple, asymptomatic, well demarcated, flat, hypopigmented atrophic macular skin lesions distributed over upper trunk and proximal upper limbs. Histopathological examination reveals atrophic epidermis with decreased basal pigmentation, perivascular mononuclear infiltration in the upper dermis, and disorganized, hyalinized, coarse collagen bundles, and variable loss of elastic fibers in the dermis. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A rare, acquired, dermis elastic tissue disorder characterized by multiple, asymptomatic, firm, well-demarcated, nonfollicular, hypopigmented or skin-colored papules, with a diameter of less than 1 cm, distributed symmetrically over trunk and/or proximal limbs (rarely, head, neck, shoulders, armpits, thighs), with no extracutaneous manifestations. Histopathology typically reveals decreased and fragmented elastic fibers, thickened and/or homogenized collagen bundles and, in some, a mild, perivascular, lymphocytic infiltrate in the dermis. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare multiple congenital anomalies syndrome characterized by congenital hearing impairment, small or absent nails on the hands and feet, and small or absent terminal phalanges. |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
5 |
Flushing of face caused by spicy food (finding) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
2 |
A rare ectodermal dysplasia syndrome characterized by linear hypopigmentation and hypotrichosis following the lines of Blaschko, symmetric or asymmetric facial dysmorphism, and body asymmetry, in association with ocular, dental, and acral anomalies. Reported manifestations include microphthalmia, strabismus, myopia, oligodontia, microdontia, conical teeth, abnormal enamel, brachydactyly, syndactyly, and broad first toe, as well as dysmorphic facial features such as downslanting palpebral fissures, broad nasal bridge, malar hypoplasia, and microstomia. Brain imaging may show cystic leukoencephalopathy and ventricular dilation. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
A rare inherited cancer-predisposing syndrome characterized by early-onset hepatocellular carcinoma, genomic instability, and progeroid features, such as short stature, low body weight, muscular atrophy, lipodystrophy, bilateral cataracts, and premature hair graying. Dysmorphic craniofacial features include triangular face, small, deep-set eyes, and micrognathia. Kyphoscoliosis, sloping shoulders, mild pectus excavatum, bilateral contractures of the elbows and fingers, bilateral clinodactyly, and pes planus have also been reported. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Venom-induced angioedema-urticaria (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Food-induced angioedema-urticaria (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Hevea brasiliensis latex protein-induced angioedema-urticaria |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Non-prepucial skin flap reconstruction of urethra |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare genetic systemic or rheumatologic disease characterized by infantile onset of skin anomalies (such as delayed wound healing with atrophic scars and mild alopecia with dry and brittle hair), retinal rod degeneration with night blindness, degenerative myopathy with muscle weakness, myalgia, and cramps, osteoarthritis, joint laxity, prolapse of internal organs, floating kidney syndrome, malabsorption syndrome, and hypothyroidism. The phenotype has been reported to be more severe in women than in men. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Injection of drug or medicament into skin |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Vacuum assisted skin closure (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Keloid acne scar (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Keloid acne scar (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A rare, genetic, primary lipodystrophy syndrome characterized by severe developmental delay and intellectual disability, hypertonia, hyperreflexia, microcephaly, tightly adherent skin, an aged appearance, severe generalized lipodystrophy, and distinct facial dysmorphism which includes large prominent eyes, narrow nasal bridge, tented upper lip vermilion, an open mouth, and high-arched palate. Laboratory analysis of serum and urine are normal. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
A rare monogenic form of cutaneous lupus erythematosus characterised by infantile or childhood onset of cold-induced erythematous papules or plaques predominantly on the fingers, toes, nose, cheeks, and ears. Recurrent ulceration of the lesions may lead to necrotic tissue destruction and mutilation. Patients may experience ischaemia of the affected acral regions. Histological findings include cutaneous perivascular inflammatory infiltrates with deposits of immunoglobulins or complement. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare, genetic, dermis elastic tissue disorder characterized by yellowish skin papules (resembling pseudoxanthoma elasticum) located on the neck, chest and/or flexural areas associated with loose, redundant, sagging skin on trunk and upper limbs, and retinitis pigmentosa, in the absence of clotting abnormalities. Patients present reduced night and peripheral vision, as well as optic nerve pallor, retinal pigment epithelium loss, attenuated retinal vessels and/or black pigment intra-retinal clumps. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Localized lichen myxedematosus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Localized lichen myxedematosus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Self-healing juvenile cutaneous mucinosis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Acral persistent papular mucinosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Hypercyanotic spell due to congenital heart disease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
A rare, genetic, skin tumor disorder characterized by childhood-onset of multiple, benign, asymptomatic, white to flesh-colored papules predominantly located on the face, ears, neck and trunk, not associated with systemic organ involvement, malignancies or FLCN gene locus mutation. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare acquired skin disease characterized by benign proliferation of mature plasma cells with a typical triad of cutaneous lesions, polyclonal hypergammaglobulinemia, and superficial lymphadenopathy, without an apparent underlying cause. The skin lesions consist of multiple round-to-oval, red-to-dark-brown macules, papules, and plaques most commonly found on the trunk, but also the face, neck, and axillae. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare genetic skin disease characterised by infantile onset of diffuse alopecia, abnormal skin pigmentation (hypo- and hyperpigmented macules of the trunk and face and areas of reticular hypo- and hyperpigmentation of the extremities), palmoplantar keratoderma, and nail dystrophy. Patients develop recurrent spinocellular carcinomas later in life. Brittle teeth resulting in early loss of dentition have also been described. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
6 |
Cleaning of external fixation site with change of dressing (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Cleaning of external fixation site with change of dressing (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Cleaning of tube insertion site with maintenance of tube and change of dressing (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Cleaning of tube insertion site with maintenance of tube and change of dressing (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Application of skin protector |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Skin care of the radiation field. |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Replacement of dressing of insertion site of cannula (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Replacement of dressing of insertion site of vascular catheter (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Progressive pigmentary dermatosis of Schamberg |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Progressive pigmentary dermatosis of Schamberg |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
Pigmented purpuric dermatosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Pigmented purpuric dermatosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Purpura annularis telangiectodes of Majocchi |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Purpura annularis telangiectodes of Majocchi |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
Eczematid-like purpura of Doucas and Kapetanakis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
Purpura pigmentosa chronica |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Purpura pigmentosa chronica |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Lichen aureus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
Lichen aureus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
7 |
Pigmented purpuric dermatosis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Lichen aureus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
8 |
A rare skin disease characterized by a hamartomatous epidermal lesion presenting as a linear array of verrucous, hyperkeratotic papules that often coalesce into plaques and are formed along the lines of Blaschko. The condition is associated with involvement of other organ systems, mainly brain, eye, and skeletal system. It is the result of mosaic post-zygotic mutations and most commonly presents at birth, but may occur anytime during childhood, rarely also in adulthood. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare vascular tumor characterized by an ill-defined, slowly growing, asymptomatic cutaneous plaque or nodule mostly involving the limbs, in fewer cases the trunk. The tumor is composed of lymphatic-like channels with prominent intraluminal papillary tufts with hyaline cores lined by hobnail endothelial cells. It is locally aggressive, while metastasis is rare. Infants and children are much more often affected than adults. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare dystrophic epidermolysis bullosa (DEB) characterized by generalized blistering, milia formation, atrophic scarring, and dystrophic nails. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Psychogenic skin disease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Psychogenic sensory disturbance of skin (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Psychogenic formication (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Psychogenic skin symptoms |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Reconstruction using nasolabial flap of skin (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Pyogenic arthritis-pyoderma gangrenosum-acne syndrome is a rare pleiotropic autoinflammatory disorder of childhood, primarily affecting the joints and skin. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by coumarin (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Cleaning of sutured wound with change of dressing (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Cleaning of sutured wound with change of dressing (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Dermatosis caused by immunosuppressant |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Ecthyma caused by Staphylococcus aureus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Ecthyma caused by Streptococcus pyogenes (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Contact dermatitis caused by latex |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Urticaria multiforme |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by lice (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Caterpillar dermatitis (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by moth and/or butterfly |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by Insecta (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by spider (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by scorpion |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by beetle (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by Arachnida |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by tick |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by Hymenoptera |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by harvest mite (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by plant mite (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by flea (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by follicle mite |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Demodectic blepharitis (disorder) |
Finding site |
False |
Skin structure |
Inferred relationship |
Some |
1 |
Dermatosis caused by Echinoidea (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Disinfection of skin |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Erythema multiforme major (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Progressive macular hypomelanosis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Progressive macular hypomelanosis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Optical dermatoscopy of skin (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Digital dermatoscopy of skin |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A form of Ehlers-Danlos syndrome (EDS) with characteristics of extreme skin fragility and laxity, a prominent facial gestalt, excessive bruising and sometimes major complications due to visceral and vascular fragility. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Ultrasonography guided puncture and aspiration of skin |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Incision and drainage of skin and subcutaneous tissue (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Allergic contact dermatitis caused by automotive grease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Contact dermatitis caused by automotive grease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Irritant contact dermatitis caused by automotive grease |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Ecthyma |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Ecthyma |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Ecthyma caused by Staphylococcus aureus |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Ecthyma caused by Streptococcus pyogenes (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Skin pigmentation (finding) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A rare genetic skin disease characterized by generalized skin peeling or superficial blisters without scarring, leukonychia, acral punctate keratoses coalescing into focal keratoderma on the weight-bearing areas, painful angular cheilitis, and knuckle pads with multiple hyperkeratotic micropapules. The skin appears dry and scaly with superficial exfoliation and underlying erythema. Histopathologic examination of affected skin areas is not specific and shows hyperkeratosis, acanthosis, and occasional intraepidermal clefting with irregular acantholysis. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |