Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Segmental pigmentation disorder |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare, syndromic, benign, epidermal nevus syndrome characterized by the association of a Becker nevus (i.e. circumscribed, unilateral, irregularly shaped, hyperpigmented macules, with or without hypertrichosis and/or acneiform lesions, occurring predominantly on the anterior upper trunk or scapular region) with ipsilateral breast hypoplasia or other, typically hypoplastic, skeletal, cutaneous, and/or muscular defects. These include pectoralis major hypoplasia, supernumerary nipples, vertebral defects, scoliosis, limb asymmetry, odontomaxillary hypoplasia and lipoatrophy. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare, syndromic, benign, epidermal nevus syndrome characterized by the association of a Becker nevus (i.e. circumscribed, unilateral, irregularly shaped, hyperpigmented macules, with or without hypertrichosis and/or acneiform lesions, occurring predominantly on the anterior upper trunk or scapular region) with ipsilateral breast hypoplasia or other, typically hypoplastic, skeletal, cutaneous, and/or muscular defects. These include pectoralis major hypoplasia, supernumerary nipples, vertebral defects, scoliosis, limb asymmetry, odontomaxillary hypoplasia and lipoatrophy. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A rare form of neurofibromatosis characterised by the development of multiple schwannomas (nerve sheath tumours), without involvement of the vestibular nerves, and often associated with chronic pain. Dysaesthesia and paraesthesia may also be present. Common localisations include the spine, peripheral nerves, and the cranium. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A rare syndromic optic nerve hypoplasia with characteristics of coloboma, osteopetrosis (particularly of the anterior ribs and femoral heads), severe microphthalmia, macrocephaly, albinism, and profound congenital deafness. Patients may also have additional eye anomalies including microcornea with pannus, dense bilateral cataracts, and translucent irides. Craniofacial dysmorphism (including frontal bossing, shallow orbits, preauricular pits, posteriorly rotated ears, micrognathia and wide palatine ridges) is also reported. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
3 |
Metastatic amelanotic malignant melanoma to skin (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Specimen from crust on skin (specimen) |
Specimen source topography |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Transdermal administration of carbon dioxide (procedure) |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
PUVA acne |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
A rare inherited epidermolysis bullosa (EB) characterized by skin fragility and blistering at birth followed by development of photosensitivity and progressive poikilodermatous skin changes. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
A large, local allergic reaction following a mosquito bite often accompanied by systemic symptoms such as a fever. Symptoms usually occur within hours of the mosquito bite and are caused by an immunologic response to proteins in mosquito saliva. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Metastatic Merkel cell carcinoma to skin (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare hyper-IgE syndrome characterised by early-onset moderate to severe atopic dermatitis and recurrent infections of variable severity including molluscum contagiosum, pneumonia, abscesses, bacteraemia, or eczema herpeticum, among others. Other reported manifestations include asthma, food allergies, colitis, chronic diarrhoea, lymphoma, and seizures, as well as dysmorphic facial features, such as prominent forehead, broad nose, and poor dentition. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
PAPASH syndrome |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare autoinflammatory syndrome with characteristics of a chronic-relapsing course of the combination of pyoderma gangrenosum, acne, hidradenitis suppurativa (which, in addition to axillae and inguinal folds, can be observed on upper and lower limbs, back, and buttocks, among others), and ankylosing spondylitis. Typical age of onset is adolescence to young adulthood, with the different signs and symptoms appearing simultaneously or subsequently. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare autoinflammatory syndrome with characteristics of the combination of psoriatic arthritis, pyoderma gangrenosum, acne, and suppurative hidradenitis (which, in addition to axillae and inguinal folds, can be observed in other areas, such as the buttocks or labia majora). |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Clark's melanoma level of invasion of excised malignant melanoma of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Distance of in situ melanoma from closest lateral surgical margin in excised specimen of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Distance of Merkel cell carcinoma from closest deep surgical margin in excised specimen of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Distance of Merkel cell carcinoma from closest peripheral surgical margin in excised specimen of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Anatomic location directly invaded by primary Merkel cell carcinoma of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Breslow depth staging for melanoma of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Deep surgical margin closest to Merkel cell carcinoma of skin in excised skin specimen (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Histologic type of malignant melanoma of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Histologic type of neoplasm of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Distance of malignant melanoma of skin from closest deep margin in excised skin specimen (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Distance of melanoma in situ of skin from closest peripheral margin in excised skin specimen |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Peripheral surgical margin closest to Merkel cell carcinoma of skin in excised skin specimen |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of direct invasion by malignant melanoma of skin to lymphatic vessel and/or small blood vessel |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of direct invasion by primary Merkel cell carcinoma of skin to lymphatic vessel and/or small blood vessel (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of Merkel cell carcinoma at surgical margin in excised specimen of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of malignant melanoma at deep surgical margin in excised specimen of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of malignant melanoma at surgical margin in excised specimen of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of melanoma in situ at surgical margin in excised specimen of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of neoplasm of skin at peripheral surgical margin in excised specimen of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Neurotropism is defined as the presence of melanoma cells abutting nerve sheaths usually circumferentially (perineural invasion) or within nerves (intraneural invasion). |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of neoplasm at deep surgical margin in excised specimen of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of regression of primary malignant melanoma of skin (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Radial location of malignant melanoma in peripheral surgical margin of excised specimen of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Radial location of melanoma in situ in peripheral surgical margin of excised skin specimen (observable entity) |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Surgical margin involved by Merkel cell carcinoma in excised skin specimen |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Temperature of skin |
This attribute specifies the independent continuant which bears the quality, and on which the dependent quality (of this observable) depends. |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Surgical margin involved by malignant melanoma in excised skin specimen |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Presence of ulcer in primary malignant melanoma of skin |
This attribute specifies the location of the entity specified by the attribute "Inheres in". |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Incontinence-associated dermatitis |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Asymptomatic carrier of infectious organism on skin |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Familial benign glomus tumour of skin |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Benign glomus tumor of skin |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Scar of skin following first vaccination (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Delayed hypersensitivity skin test for diphtheria |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Trichinella extract skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for tetanus |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for Candida albicans |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Lepromin H skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Lepromin A skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Delayed hypersensitivity skin test for phytohemagglutinin |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test, multitest |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Patch test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Skin test for tuberculosis, Tine test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for coccidiodin |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for SK-SD |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Brucellosis skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Skin testing: metals (procedure) |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Echinococcus extract skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Intradermal test of type 1 hypersensitivity (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Subcutaneous test of type 1 hypersensitivity |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Closed patch test - European standard series |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Closed patch test - extended series |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Open patch test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Scratch patch test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Photo patch test (procedure) |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Streptococcus skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Glycerin skin test (procedure) |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Proteus skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Heaf test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Leishmania skin test |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Prick test |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for tuberculin PPD |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Mantoux test (procedure) |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Delayed hypersensitivity skin test for staphage lysate |
Procedure site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Type 1 hypersensitivity skin test |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare hyper-IgE syndrome with characteristics of atopic dermatitis (eczema), chronic mucocutaneous candidiasis, and elevated IgE levels due to ZNF341 deficiency. High plasma levels of IgG and low natural killer (NK) cell numbers are observed. Other major clinical features involve recurrent skin infections with skin abscesses and connective tissue abnormalities. Some patients may have recurrent lung infections. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Drug-induced persistent light reaction |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Drug-induced persistent light reaction |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
5 |
External radiation therapy using superficial radiation (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Grenz ray therapy |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Superficial radiation therapy |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Grenz ray therapy up to 10 kV |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Superficial X-ray therapy 10-60 kV |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Half-deep therapy 60-150 kV |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Radionecrosis of skin due to and following radiotherapy |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
A rare genetic autoinflammatory syndrome with skin involvement characterised by cold-induced urticarial rash without angioedema starting in infancy and systemic inflammation due to autosomal dominant mutations in the coagulation factor 12 (F-12) gene. In addition to cold-induced, non-pruritic urticarial rash, patients present with headache, mild to severe arthralgia, fatigue, subfebrile evening temperature, chills, and malaise. Systemic symptoms worsen during the cold season and over the years. |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
2 |
Carney complex-associated-primary pigmented nodular adrenocortical disease (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
4 |
Cleaning of wound of skin (procedure) |
Procedure site - Direct (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Hemangioblastoma of skin |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Application of L-PRF (leukocyte-platelet rich fibrin) to wound |
Procedure site - Indirect (attribute) |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Darier sign |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Infection of skin caused by Balamuthia (disorder) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Rope sign (finding) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |
Shawl sign (finding) |
Finding site |
True |
Skin structure |
Inferred relationship |
Some |
1 |