Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Chronic pelvic pain of prostatic origin without infection or inflammation. |
Associated morphology |
False |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Chronic bacterial prostatitis. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Osteomyelitis caused by Salmonella enterica enterica serovar Typhi (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Periodontitis exacerbated by Cohen syndrome |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by Down syndrome |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis due to infantile genetic agranulocytosis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by hypophosphatasia (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by glycogen storage disease |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Irritant contact dermatitis due to fistula (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Irritant contact dermatitis due to mucous fistula (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic immune disease characterized by recurrent sinopulmonary infections and autoimmune enterocolopathy, manifesting as frequent episodes of intractable diarrhea with abdominal pain and fever, accompanied by eczematous rashes, due to deficits in components of innate and adaptive immunity. Immunologic abnormalities include IgG subclass deficiency, impaired antigen-induced lymphocyte proliferation, reduced cytokine production by CD8+ T lymphocytes, and decreased numbers of natural killer cells. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic immune disease characterized by early onset of recurrent bacterial, viral, and fungal infections, chronic inflammatory bowel disease, gastritis, and inflammatory polyarthritis. Patients present with diarrhea, vomiting, hepatosplenomegaly, mouth ulcers, perianal abscesses, chronic lung disease with bronchiectasis, and failure to thrive. Occurrence of a skin rash associated with lymphocytic vasculitis has also been reported. Immunologic abnormalities include variable T-cell lymphopenia, decreased natural killer cells, and decreased B-cells with variable hypogammaglobulinemia. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic immune disease characterized by early onset of recurrent bacterial, viral, and fungal infections, chronic inflammatory bowel disease, gastritis, and inflammatory polyarthritis. Patients present with diarrhea, vomiting, hepatosplenomegaly, mouth ulcers, perianal abscesses, chronic lung disease with bronchiectasis, and failure to thrive. Occurrence of a skin rash associated with lymphocytic vasculitis has also been reported. Immunologic abnormalities include variable T-cell lymphopenia, decreased natural killer cells, and decreased B-cells with variable hypogammaglobulinemia. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
A rare genetic autoinflammatory syndrome with immune deficiency characterized by a combination of autoinflammation, immunodeficiency, and neutrophil dysfunction, as well as mild bleeding diathesis. Patients present recurrent attacks of abdominal pain, high fever, and systemic inflammation lasting four to five days and occurring every few weeks. Attacks may be accompanied by nailbed, tongue, submandibular, and gluteal abscesses, intra-abdominal granulomas, pyoderma gangrenosum, and buccal ulcerations. Frequent episodes of purulent paronychia, superficial skin and mucosal infections, and purulent upper respiratory tract infections have also been reported. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic disease characterized by infantile onset of severe inflammatory bowel disease manifesting with bloody diarrhea and failure to thrive, and central nervous system disease with global developmental delay and regression, impaired speech, hypotonia, hyperreflexia, and epilepsy. Brain imaging shows global cerebral atrophy, thin corpus callosum, delayed myelination, and posterior leukoencephalopathy. Cases with recurrent infections and impaired T-cell responses to stimulation, as well as decreased T-cell subsets, have been reported. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Pediatric multiple sclerosis (MS) is a rare multiple sclerosis variant characterized by the onset of multiple sclerosis (i.e. one or multiple episodes of clinical CNS symptoms consistent with acquired CNS demyelination, with radiologically proven dissemination of inflammatory lesions in space and time, following exclusion of other disorders) before the age of 18 years old. Pediatric MS patients present a predominantly relapsing-remitting course with first attack usually consisting of optic neuritis, transverse myelitis, acute disseminated encephalomyelitis and monofocal or polyfocal neurological deficits. A high burden of T2-hyperintense lesions on initial MRI, primarily of the supratentorial region and/or of the cervical spinal cord, has been reported. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Thyroiditis caused by radiation due to and following iodine 131 treatment (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Immunoglobulin G4 related hypophysitis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by chronic familial neutropenia |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by cyclical neutropenia (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by acquired neutropenia |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis due to Ehlers-Danlos syndrome type 4 (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis due to leukocyte adhesion deficiency |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by familial neutropenia |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Lymphocytic colitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Hereditary paediatric Behçet-like disease |
Associated morphology |
False |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by Chédiak-Higashi syndrome (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Periodontitis exacerbated by human immunodeficiency virus infection (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Gingivitis artefacta |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
3 |
Noninfective enteritis and colitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Phlegmonous gastritis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Phlegmonous oesophagitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Phlegmonous colitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
A rare renal disease occurring in the setting of a systemic IgG4 related disease (IgG4-RD). The disorder is characterized by a fibrosing tubulointerstitial nephritis consisting of predominantly IgG4+ plasma cells with/without glomerulonephritis, retroperitoneal fibrosis and hydronephrosis. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare renal disease occurring in the setting of a systemic IgG4 related disease (IgG4-RD). The disorder is characterized by a fibrosing tubulointerstitial nephritis consisting of predominantly IgG4+ plasma cells with/without glomerulonephritis, retroperitoneal fibrosis and hydronephrosis. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
A rare systemic autoimmune disease characterized by infiltrates of IgG4-positive plasma cells and lymphocytes in the adventitia of the aorta, resulting in thickening of perivascular tissue or formation of soft tissue masses surrounding the aorta and its major branches (potentially complicated by inflammatory aortic aneurysm), associated with elevated serum IgG4 levels. Preferential location is the infra-renal portion of the abdominal aorta. In addition, medium-sized blood vessels can be involved, and the condition may occur together with IgG4-related disease in other parts of the body. Clinical symptoms are unspecific and include chest or back pain and fever. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare, inflammatory eye disease characterized by IgG4-immunopositive lymphocyte and plasmacyte infiltration and collagenous fibrosis of affected tissue and elevated serum levels of IgG4. Clinical presentation includes mass lesion or swelling of the involved structures, commonly involving lacrimal gland and duct, infraorbital and supraorbital nerves, extraocular muscles and orbital soft tissues. A systemic involvement is common. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Allergic contact gingivostomatitis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
A rare systemic disease characterized by acute or subacute onset of thrombocytopenia, anasarca (edema, pleural effusion, ascites), and systemic inflammation (fever and/or elevated C-reactive protein). Minor diagnostic categories are Castleman's disease-like features on lymph node biopsy, reticulin myelofibrosis and/or increased number of megakaryocytes in bone marrow, progressive renal insufficiency, and mild organomegaly including hepatosplenomegaly and lymphadenopathy. Most patients show elevated levels of serum alkaline phosphatase, while marked polyclonal hypergammopathy is rare. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
4 |
Renal tubulo-interstitial disorder due to cystinosis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Renal tubulo-interstitial disorder due to cystinosis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Inflammation of intestine (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Viral gastroenteritis caused by Sapovirus |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Viral gastroenteritis caused by Sapovirus |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Chronic inflammation of small intestine caused by radiation (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Aspergillosis enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Aspergillosis enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Blastomycotic enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Blastomyces dermatitidis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enterohemorrhagic Escherichia coli enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by enterohemorrhagic Escherichia coli (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enteroinvasive Escherichia coli enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by enteroinvasive Escherichia coli (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enteropathogenic Escherichia coli enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by enteropathogenic Escherichia coli (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by enterotoxigenic Escherichia coli (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by enterotoxigenic Escherichia coli (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Actinomycotic enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Actinomycotic enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enterobacterial enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by methicillin-resistant Staphylococcus aureus (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by methicillin-resistant Staphylococcus aureus (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enterobacterial enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by Mycobacterium (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Non-tuberculous mycobacterial enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Mycobacterial enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Non-tuberculous mycobacterial enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by Shigella boydii (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Shigella boydii (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Shigella dysenteriae (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Shigella dysenteriae enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Shigella flexneri (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Shigella sonnei enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Vibrio cholerae (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by Vibrio cholerae (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Shigella sonnei enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Shigella flexneri enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine presumed infectious (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enteritis of intestine presumed infectious |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine due to human immunodeficiency virus disease (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Enteritis of small intestine due to human immunodeficiency virus disease |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Cryptosporidium (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by protozoan (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of small intestine caused by Entamoeba histolytica (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Cryptosporidial enteritis of intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by protozoan (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by Entamoeba histolytica (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Giardia lamblia enteritis of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of intestine caused by Giardia lamblia (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare hepatic disease characterized by recurrence of hepatitis C virus infection after liver transplantation, leading to liver injury with features resembling those observed in the non-transplant graft, and typically developing after three months post-transplantation. The clinical course is highly variable, although patients most commonly develop progressive chronic liver disease with higher viral loads and more rapid fibrosis progression than in the immunocompetent population. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Recurrent anterior uveitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Colitis caused by Chlamydia trachomatis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic disease characterized by multiple intestinal atresia in association with combined immunodeficiency and inflammatory bowel disease. Clinical features include widespread atresia extending from the stomach to the rectum, homogenous calcifications in the abdominal cavity, hepatic cholestasis, cirrhosis, and chronic liver failure, hypoplastic thymus, and increased susceptibility to mainly bacteria and viruses. The immunological phenotype consists of profound generalized T-cell lymphopenia and milder natural killer cell and B-cell lymphopenia, as well as low serum levels of IgG, IgA, and IgM, with elevated serum IgE. The disease is mostly fatal in infancy or childhood. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Inflammation of mucous membrane due to and following chemotherapy |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare genetic systemic or rheumatologic disease characterized by neonatal or infantile onset of enterocolitis (which resolves with age), periodic fever, and episodes of severe systemic inflammation, which may be precipitated by infections, stress, or fatigue. Signs and symptoms include splenomegaly, urticaria-like rashes, arthralgia, and myalgia. Associated laboratory findings are elevated inflammatory markers (such as ferritin, C-reactive protein), pancytopenia, and elevated transaminases. If left untreated, flares can progress to coagulopathy, organ failure, and death. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
2 |
A rare genetic systemic or rheumatologic disease characterized by neonatal or infantile onset of enterocolitis (which resolves with age), periodic fever, and episodes of severe systemic inflammation, which may be precipitated by infections, stress, or fatigue. Signs and symptoms include splenomegaly, urticaria-like rashes, arthralgia, and myalgia. Associated laboratory findings are elevated inflammatory markers (such as ferritin, C-reactive protein), pancytopenia, and elevated transaminases. If left untreated, flares can progress to coagulopathy, organ failure, and death. |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
3 |
Duodenitis due to celiac disease (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Duodenitis due to vasculitis |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Duodenitis due to sarcoidosis (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Behçet disease of small intestine |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
4 |
Autoimmune pancreatitis type 2 (disorder) |
Associated morphology |
True |
Inflammatory morphology (morphologic abnormality) |
Inferred relationship |
Some |
1 |