Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Entire retinal pigment epithelium |
Is a |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
|
Retinal pigment epithelial detachment |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial detachment with vascularization |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial detachment with tear of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Congenital hypertrophy of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular pigment epithelial detachment |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular retinal pigment epithelium tear (disorder) |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinoma |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Exudative detachment of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Chronic central serous retinopathy with diffuse retinal pigment epithelial detachment |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Inactive central serous retinopathy with focal retinal pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Central serous retinopathy with small retinal pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Avascular retinal pigment epithelial detachment |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Hemorrhagic detachment of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Serous detachment of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epitheliitis |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Atrophic macular change |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Macular pigment deposit |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
3 |
Macular diffuse atrophy |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Macular areolar choroidal atrophy |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Macular choroidal sclerosis |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
3 |
Herpes zoster retinal pigment epithelial detachment (disorder) |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Herpes simplex retinal pigment epithelial detachment (disorder) |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial abnormality |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelium atrophy |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial hyperplasia (disorder) |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial hypertrophy (disorder) |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Translocation of pigment epithelium of retina (procedure) |
Procedure site - Direct (attribute) |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Hemorrhagic detachment of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinoma |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Atrophic macular change |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Retinal pigment epithelial hyperplasia (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial abnormality |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Translocation of pigment epithelium of retina (procedure) |
Procedure site - Direct (attribute) |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Avascular retinal pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial hypertrophy (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Chronic central serous retinopathy with diffuse retinal pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial detachment with vascularization |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Congenital hypertrophy of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial detachment with tear of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Serous detachment of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epitheliitis |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular areolar choroidal atrophy |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Macular diffuse atrophy |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Herpes simplex retinal pigment epithelial detachment (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular pigment epithelial detachment |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelium atrophy |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular retinal pigment epithelium tear (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Herpes zoster retinal pigment epithelial detachment (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Exudative detachment of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial dystrophy |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Congenital hypertrophy of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Proliferative vitreoretinopathy |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Anterior proliferative vitreoretinopathy |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Posterior proliferative vitreoretinopathy |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
A rare, patterned dystrophy of the retinal pigment epithelium characterized by multiple yellowish irregular flecks scattered or interconnected around the macula, simulating what is observed in Stargardt disease, and usually asymptomatic until adulthood when patients present with a slowly progressive loss of vision that often only becomes apparent in old age. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
A rare, patterned dystrophy of the retinal pigment epithelium, of progressive course, characterized by the presence of a bilateral hyperpigmented reticular pattern resembling a fishnet with knots, resulting in a slowly progressive loss of vision that often only becomes apparent in old age. This disorder is sometimes associated with scleral staphyloma, choroidal neovascularization, convergent strabismus, spherophakia with myopia and luxated lenses, and partial atrophy of the iris. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Pattern dystrophy of macula |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
A rare, patterned dystrophy of the retinal pigment epithelium characterized by abnormal accumulation of lipofuscin in a butterfly-shaped distribution at the retinal pigment epithelium level. Patients manifest with a slowly progressive loss of vision that often only becomes apparent in old age. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Fundus pulverulentus is a rare form of patterned dystrophy of the retinal pigment epithelium characterized by a granular appearance in the macula, with coarse and punctiform mottling of the retinal pigment epithelium within the macular region. Association with choroidal neovascularization has been reported. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Structure of retinal pigment epithelium of right eye (body structure) |
Is a |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
|
Structure of retinal pigment epithelium of left eye |
Is a |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
|
Saldino-Mainzer dysplasia |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Hemorrhagic detachment of retinal pigment epithelium |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Exudative detachment of retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Subretinal lesion |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal hemorrhage |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal disciform lesion |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal lipid deposit |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal fibrosis |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Diffuse subretinal fibrosis |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal fibrosis and uveitis syndrome (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular subretinal hemorrhage |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Macular subretinal fibrosis |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subfoveal haemorrhage |
Finding site |
False |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Subretinal exudate |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal fluid |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Reticular pseudodrusen |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Retinal pigment epithelial adenocarcinoma |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
A rare benign eye tumor characterized by the presence of glial cells, vascular tissue, and sheets of pigment epithelial cells lacking the distribution and organization of the normal retina and retinal pigment epithelium. The lesion is most commonly found unilaterally as a slightly elevated mass in a peripapillary location but can also occur in the macula or the retinal periphery. It is sometimes associated with neurofibromatosis type 1 or 2, nevoid basal cell carcinoma syndrome, or branchio-oculo-facial syndrome. Patients may be asymptomatic or present with progressive loss of vision. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Pigmented epithelial disseminated retinitis |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Subretinal implant in situ |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Metastatic adenocarcinoma to retinal pigment epithelium (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Primary retinal pigment epithelial adenocarcinoma (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
A disorder characterized by the presence of RPE (retinal pigment epithelium) disruption within the posterior pole over regions of choroidal thickening in eyes, showing no evidence of active or prior CSC (central serous chorioretinopathy). |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Solitary congenital hypertrophy of retinal pigment epithelium (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Hereditary retinal dystrophy primarily involving retinal pigment epithelium |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
Biallelic mutation carriers have a mutation (not necessarily the same mutation) in both copies of a particular gene (a paternal and a maternal mutation). The RPE65 gene provides instructions for making an enzyme that is essential for normal vision and mutations in this gene result in reduced or absent levels of RPE65 activity, blocking the visual cycle and resulting in impaired vision. Almost all patients eventually progress to complete blindness. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |
Patchy atrophy of retinal pigment epithelium (disorder) |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
1 |
A rare, genetic retinal disease characterized by the characteristic dried-out soil fundus pattern due to diffuse deep white lines in the macula, to the level of the retinal pigment epithelium, which is slightly elevated and rippled. Macular exudation may be associated, and Bruch's membrane may be affected too. Occasionally, peripheral nummular pigmentary changes may be observed, associated with blindness. The lesions enlarge with time, with a preferential macular extension and confluence. Complications may include polypoidal choroidal vasculopathy, choroidal neovascularization or atrophic fibrous macular scarring that can lead to reduced visual acuity over time. |
Finding site |
True |
Structure of retinal pigment epithelium |
Inferred relationship |
Some |
2 |