Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Acquired anhidrosis co-occurrent and due to primary autonomic disorder (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
4 |
Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome is a rare, genetic, syndromic intellectual disability disorder characterised by severe intellectual disability with significant speech and language impairment, hypohidrosis (often resulting in hyperthermia) with normal sweat gland appearance, tooth enamel hypoplasia, palmoplantar hyperkeratosis and a high frequency of acquired microcephaly. Mild facial dysmorphism, including lateral flaring of the eyebrows, broad nasal tip, and thick vermilion border, may also be observed. |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
6 |
Hypohidrosis due to genetic abnormality of eccrine gland structure and function (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
2 |
Idiopathic pure sudomotor failure (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
2 |
Hypohidrosis of unknown etiology (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
2 |
Hypohidrosis co-occurrent and due to disorder of sympathetic nervous system (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
1 |
A rare genetic skin disease characterized by congenital generalized anhidrosis resulting in severe heat intolerance, due to functionally impaired eccrine sweat production. Skin biopsy reveals normal morphology and number of sweat glands. Dental, hair, nail, or other skin or extracutaneous anomalies are absent. |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
2 |
A rare genetic disease characterised by abnormalities in renal ion transport, ectodermal gland homeostasis, and epidermal integrity, resulting in generalised hypohidrosis, heat intolerance, salt-losing nephropathy, electrolyte imbalance, lacrimal gland dysfunction, ichthyosis, and xerostomia. Development of nephrolithiasis and severe enamel wear have also been described. Laboratory findings include hypermagnesaemia, hypokalaemia, hypercalcaemia, and hypocalciuria. |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
3 |
Drug-induced hyperhidrosis |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
2 |
Hypohidrosis due to neurological disorder (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
1 |
Localized hyperhidrosis due to focal neurological disorder (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
1 |
Menopausal hyperhidrosis (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
1 |
A rare hereditary sensory and autonomic neuropathy characterized by congenital insensitivity to pain, general hypesthesia, diminished temperature sensitivity, and hyperhidrosis. Motor function is preserved. Skin biopsy reveals lack of cutaneous innervation except for sensory and autonomic innervation of blood vessels and sweat glands. |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
1 |
A rare ectodermal dysplasia syndrome characterized by hypotrichosis, tooth enamel hypoplasia, hypoplastic nails, palmoplantar keratoderma, hyperhidrosis on hands, face, and scalp, bilateral partial cutaneous syndactyly, and dysmorphic facial features with large prominent ear pinnae, pointed nose, and thin upper lips. Association of cardiomegaly has also been reported. |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
9 |
Anhidrotic ectodermal dysplasia with immune deficiency due to IKBA gain of function mutation |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
5 |
Anhidrotic ectodermal dysplasia with immune deficiency due to IKBKB gain of function mutation (disorder) |
Interprets |
True |
Sweating, function (observable entity) |
Inferred relationship |
Some |
4 |