425820005: Lapatinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\...

\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Lapatinib (substance)

\Protein-tyrosine kinase inhibitor\Lapatinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Lapatinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinazoline (substance)\Lapatinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2007. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

2663008017 Lapatinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2674877019 Lapatinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

370061000195112 lapatinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

819941000172117 lapatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

2376481000195110 Lapatinib de Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lapatinib (substance)	Is a	Quinazoline (substance)	true	Inferred relationship	Some
Lapatinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Lapatinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Lapatinib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Lapatinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Lapatinib (substance)	Is a	Epidermal growth factor receptor inhibitor	false	Inferred relationship	Some
Lapatinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Epidermal growth factor receptor inhibitor	false	Inferred relationship	Some
Lapatinib (substance)	Is a	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Lapatinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Lapatinib ditosylate (substance)	Is a	False	Lapatinib (substance)	Inferred relationship	Some
Tykerb	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lapatinib (substance)	Inferred relationship	Some
Product containing lapatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lapatinib (substance)	Inferred relationship	Some	1
Lapatinib ditosylate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Lapatinib (substance)	Inferred relationship	Some
Lapatinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lapatinib (substance)	Inferred relationship	Some	1
Lapatinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lapatinib (substance)	Inferred relationship	Some	1
Lapatinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Lapatinib (substance)	Inferred relationship	Some	1
Product containing precisely lapatinib (as lapatinib ditosylate) 250 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Lapatinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets