426238006: Lapatinib ditosylate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\...

\Epidermal growth factor receptor inhibitor\Lapatinib ditosylate (substance)

\Protein-tyrosine kinase inhibitor\Lapatinib ditosylate (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Epidermal growth factor receptor inhibitor\Lapatinib ditosylate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinazoline (substance)\Lapatinib ditosylate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2007. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

2663017017 Lapatinib ditosylate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2674886012 Lapatinib ditosylate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

40111000188117 Lapatinib ditosylate fr Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Lapatinib ditosylate (substance)	Is a	Lapatinib (substance)	false	Inferred relationship	Some
Lapatinib ditosylate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Lapatinib ditosylate (substance)	Is a	Quinazoline (substance)	true	Inferred relationship	Some
Lapatinib ditosylate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Lapatinib (substance)	true	Inferred relationship	Some
Lapatinib ditosylate (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Lapatinib ditosylate (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Lapatinib ditosylate (substance)	Is a	Epidermal growth factor receptor inhibitor	true	Inferred relationship	Some
Lapatinib ditosylate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Epidermal growth factor receptor inhibitor	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely lapatinib ditosylate 250 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lapatinib ditosylate (substance)	Inferred relationship	Some
Lapatinib ditosylate monohydrate (substance)	Is a	False	Lapatinib ditosylate (substance)	Inferred relationship	Some
Product containing precisely lapatinib ditosylate 250 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Lapatinib ditosylate (substance)	Inferred relationship	Some	1
Product containing precisely lapatinib ditosylate 250 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Lapatinib ditosylate (substance)	Inferred relationship	Some	1
Lapatinib ditosylate monohydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Lapatinib ditosylate (substance)	Inferred relationship	Some
Product containing precisely lapatinib ditosylate 250 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Lapatinib ditosylate (substance)	Inferred relationship	Some	1
Product containing precisely lapatinib (as lapatinib ditosylate) 250 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Lapatinib ditosylate (substance)	Inferred relationship	Some	1
Lapatinib ditosylate anhydrous	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Lapatinib ditosylate (substance)	Inferred relationship	Some

This concept is not in any reference sets