430478003: Macrophage activation syndrome (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Finding of blood, lymphatics and immune system\Disorder of cellular component of blood (disorder)\White blood cell disorder\Qualitative abnormality of granulocyte\Combined phagocytic defect\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)

\Disease\Disorder of immune function (disorder)\Immunodeficiency disorder\Primary immune deficiency disorder\Phagocytic cell defect\Phagocytic cell dysfunction (disorder)\Combined phagocytic defect\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)
\Disease\Disorder of immune function (disorder)\White blood cell disorder\Qualitative abnormality of granulocyte\Combined phagocytic defect\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)
\Disease\Disorder of hematopoietic cell proliferation (disorder)\Histiocytic syndrome\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)
\Disease\Disorder of cellular component of blood (disorder)\White blood cell disorder\Qualitative abnormality of granulocyte\Combined phagocytic defect\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)
\Disease\Disorder of body system\Disorder of immune structure (disorder)\Combined phagocytic defect\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)
\Disease\Disorder of body system\Disorder of hematopoietic structure (disorder)\Haemophagocytic lymphohistiocytosis\Macrophage activation syndrome (disorder)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2008. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Macrophage activation syndrome (disorder)	Is a	Hemophagocytic syndrome	false	Inferred relationship	Some
Macrophage activation syndrome (disorder)	Associated morphology	Histiocytic proliferation - category	false	Inferred relationship	Some	3
Macrophage activation syndrome (disorder)	Associated with	Autoimmune disease	false	Inferred relationship	Some	1
Macrophage activation syndrome (disorder)	Finding site	Mononuclear phagocyte system structure (body structure)	false	Inferred relationship	Some	2
Macrophage activation syndrome (disorder)	Is a	Haemophagocytic lymphohistiocytosis	true	Inferred relationship	Some
Macrophage activation syndrome (disorder)	Pathological process (attribute)	Abnormal immune process (qualifier value)	false	Inferred relationship	Some	4
Macrophage activation syndrome (disorder)	Pathological process (attribute)	Abnormal immune process (qualifier value)	false	Inferred relationship	Some	2
Macrophage activation syndrome (disorder)	Associated morphology	Histiocytic proliferation - category	false	Inferred relationship	Some	2
Macrophage activation syndrome (disorder)	Finding site	Mononuclear phagocyte system structure (body structure)	true	Inferred relationship	Some	1
Macrophage activation syndrome (disorder)	Associated morphology	Histiocytic proliferation (morphologic abnormality)	true	Inferred relationship	Some	1
Macrophage activation syndrome (disorder)	Pathological process (attribute)	Abnormal immune process (qualifier value)	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Macrophage activation syndrome due to juvenile systemic onset arthritis	Is a	True	Macrophage activation syndrome (disorder)	Inferred relationship	Some
A rare genetic systemic or rheumatologic disease characterized by neonatal or infantile onset of enterocolitis (which resolves with age), periodic fever, and episodes of severe systemic inflammation, which may be precipitated by infections, stress, or fatigue. Signs and symptoms include splenomegaly, urticaria-like rashes, arthralgia, and myalgia. Associated laboratory findings are elevated inflammatory markers (such as ferritin, C-reactive protein), pancytopenia, and elevated transaminases. If left untreated, flares can progress to coagulopathy, organ failure, and death.	Is a	True	Macrophage activation syndrome (disorder)	Inferred relationship	Some
Macrophage activation syndrome due to infectious disease (disorder)	Is a	True	Macrophage activation syndrome (disorder)	Inferred relationship	Some

This concept is not in any reference sets

Back to Start

Id	Description	Lang	Type	Status	Case?	Module
2709067014	Macrophage activation syndrome (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
2765378013	Macrophage activation syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4592287013	Reactive haemophagocytic syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4592288015	Haemophagocytic lymphohistiocytosis with rheumatologic disease	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4592289011	Hemophagocytic lymphohistiocytosis with rheumatologic disease	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
4592290019	Reactive hemophagocytic syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
878531000172119	syndrome d'activation macrophagique	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
173791000274118	Makrophagen-Aktivierungssyndrom	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
173801000274119	MAS - Makrophagen-Aktivierungssyndrom	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module