Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Vitamin B12 deficiency anemia due to chronic atrophic gastritis (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Lymphocyte passenger syndrome following organ transplantation |
Interprets |
False |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Acute sequestration of spleen due to sickle cell thalassemia with crisis (disorder) |
Interprets |
False |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
6 |
Acute splenic sequestration due to sickle cell hemoglobin C disease with crisis |
Interprets |
False |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
6 |
Vitamin B12 deficiency anemia following total gastrectomy (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Pernicious anaemia due to autoimmune disorder |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Mechanical hemolysis following insertion of prosthetic heart valve (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
4 |
Aase syndrome |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Antibody mediated acquired pure red cell aplasia caused by erythropoiesis stimulating agent (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Thalassemia major |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Delta beta zero thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta plus thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha zero thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hb Lepore thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Epsilon gamma delta beta^0^ thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hereditary persistence of fetal hemoglobin G gamma beta plus thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Thalassemia-hemoglobin C disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Delta zero thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha plus thalassemia non deletion type (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
HPFH deletion type |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha plus thalassaemia deletion type |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta zero thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
HPFH linked to beta-globulin gene cluster |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
^A^gamma delta beta^0^ thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hereditary persistence of fetal hemoglobin, nondeletion type (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Thalassemia syndrome |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hereditary persistence of fetal hemoglobin delta beta plus thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Epsilon gamma delta beta thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha plus thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Sickle cell-thalassemia disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
HPFH A gamma beta^+^ thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
HPFH unlinked to beta-globulin gene cluster |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Homozygous beta thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta zero thalassemia deletion type |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Thalassemia with other hemoglobinopathy |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta plus thalassemia normal hemoglobin A>2< type 1 silent (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin H disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
beta^+^ Thalassemia, normal Hb A>2<, type 2 |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Delta beta thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Delta thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hereditary persistence of fetal hemoglobin thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Heterozygous thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
A>gamma< beta^+^ HPFH AND beta^0^ thalassaemia in cis |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Thalassemia intermedia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta zero thalassemia non deletion type (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Sickle cell-hemoglobin SS disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
1 |
Sickle cell trait with coexistent alpha-thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha trait thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta thalassaemia intermedia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Homozygous alpha thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha thalassemia-2 trait |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Haemoglobin Constant Spring trait |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin Lepore trait |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Delta-beta-Lepore thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Alpha-beta thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Gamma thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Sickle cell anemia with high hemoglobin F |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Beta thalassaemia trait |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Acquired haemoglobin H disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin SS disease with vasoocclusive crisis (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
1 |
A rare X-linked syndromic intellectual disability characterized by profound developmental delay, facial dysmorphism, genital abnormalities and alpha thalassemia. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Dominant beta-thalassemia is a form of beta-thalassemia resulting in moderate to severe anemia. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin H constant spring thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Haemoglobin Paksé disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
1 |
Hemoglobin Seal Rock disease (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
1 |
Acute sequestration of spleen due to sickle cell thalassemia with crisis (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
4 |
Acute splenic sequestration due to sickle cell hemoglobin C disease with crisis |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
4 |
Vitamin B12 deficiency anemia following gastrectomy (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin finding |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
1 |
Hemoglobin E/beta thalassemia disease |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Upshaw-Schulman syndrome (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
4 |
Hematopoietic subsyndrome of acute radiation syndrome (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
5 |
A rare genetic hemolytic uremic syndrome (HUS) characterized by infantile onset of relapsing episodes of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The episodes are often preceded by viral infections. Affected individuals typically present persistent hypertension, hematuria, and proteinuria (sometimes in the nephrotic range) and develop chronic kidney disease with age. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
A rare type of hemolytic uremic syndrome (HUS) characterized by the triad of hemolytic anemia due to generalized thrombotic microangiopathy, thrombocytopenia, and acute kidney injury, and most commonly occurring after acute gastroenteritis due to Shiga toxin-producing enterohemorrhagic Escherichia coli or Shigella dysenteriae. Other infectious causes of HUS include Streptococcus pneumoniae, HIV, Mycoplasma pneumoniae, Histoplasmosis, and Coxsackie virus. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
A rare disorder characterized by hemolytic anemia, associated with metabolic acidosis and 5-oxoprolinuria in moderate forms, and with progressive neurological symptoms and recurrent bacterial infections in the most severe forms. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Glutathione synthase deficiency without 5-oxoprolinuria |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Fanconi anemia of complementation group C |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Haemoglobin D beta plus thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Haemoglobin E beta plus thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Haemoglobin C beta plus thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin E beta zero thalassemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hemoglobin D beta zero thalassemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Haemoglobin C beta zero thalassaemia |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Pancytopenia caused by colchicine (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Pancytopenia caused by non-steroidal anti-inflammatory agent (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Delta beta thalassemia trait (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Postpartum iron deficiency anemia (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Iron deficiency anemia during maternal intrapartum period (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Glutathione synthase deficiency with 5-oxoprolinuria |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Atypical haemolytic uraemic syndrome with complement gene abnormality |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
5 |
Atypical haemolytic uraemic syndrome with anti-factor H antibodies |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
5 |
A rare constitutional aplastic anaemia characterised by aplastic anaemia, intellectual disability, short stature, and microcephaly. Skin pigmentation or cafe au lait spots are often present. Majority of the patients present global developmental delay with impaired motor skills, learning disabilities, speech delay whereas some patients also may have behavioural problems including autistic features. Patients often develop premalignant myelodysplastic syndromes or leukaemia. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
7 |
Pancytopenia caused by antidiabetic drug (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
A rare unclassified autoinflammatory syndrome characterised by neonatal onset pancytopenia, type I interferon-dependent multisystemic autoinflammation, painful rash with variable frequencies and haemophagocytic lymphohistiocytosis. Failure to thrive, fever, gastrointestinal/upper respiratory tract infections, enterocolitis, hepatosplenomegaly, myelofibrosis and neurodevelopmental delay are other common clinical features. Facial dysmorphism including macrocephaly, mild frontal bossing, sparse hair, mild hypertelorism, depressed nasal bridge can be present. |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
4 |
Beta thalassemia major in mother complicating pregnancy |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Beta thalassemia trait in mother complicating pregnancy (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |
Alpha thalassemia trait in mother complicating pregnancy (disorder) |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
2 |
Hereditary pyropoikilocytosis |
Interprets |
True |
Measurement of total haemoglobin concentration |
Inferred relationship |
Some |
3 |