443929000: Small vessel cerebrovascular disease (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Cardiovascular finding\Disorder of cardiovascular system (disorder)\Cerebrovascular disease\Small vessel cerebrovascular disease (disorder)

\Disease\Disorder of body system\Disorder of cardiovascular system (disorder)\Cerebrovascular disease\Small vessel cerebrovascular disease (disorder)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2010. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

2836130017 Small vessel cerebrovascular disease (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

2840867019 Cerebral small vessel disease en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

2842187014 Small vessel cerebrovascular disease en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5343101000241116 maladie cérébrovasculaire des petits vaisseaux fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Small vessel cerebrovascular disease (disorder)	Is a	Cerebrovascular disease	true	Inferred relationship	Some
Small vessel cerebrovascular disease (disorder)	Finding site	Cerebrovascular system structure	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
A rare genetic neurological disorder characterized by the presence of fragile small-vessel intracerebral vasculature in various members of a single family, manifesting, clinically, with single or recurrent hemorrhagic and/or ischemic stroke and, frequently, ocular and renal involvement. Neuroimaging reveals diffuse, periventricular leukoencephalopathy associated with dilated perivascular spaces, lacunar infarction and microhemorrhages.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some
A rare genetic cerebral small vessel disease characterized by progressive loss of visual acuity due to retinal vasculopathy, in combination with more variable neurological signs and symptoms including stroke, cognitive decline, migraine-like headaches, and seizures, among others, typically beginning in middle age. Psychiatric features such as depression and anxiety may also occur. Systemic vascular involvement with Raynaud phenomenon, micronodular liver cirrhosis, and glomerular kidney dysfunction is present in a subset of patients.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some
A rare genetic cerebral small vessel disease characterized by recurrent ischemic strokes, often with a predilection for the pons, with typical onset in the fourth or fifth decade of life. Patients present progressive cognitive and motor impairment with pyramidal, bulbar, and cerebellar symptoms, among others. Brain imaging shows multiple lacunar infarcts, typically with involvement of the pons, as well as variable leukoencephalopathy of the cerebral hemispheres.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some
A rare genetic cerebral small vessel disease characterized by leukoencephalopathy and cerebral calcification and cysts due to diffuse cerebral microangiopathy resulting in microcystic and macrocystic parenchymal degeneration. The condition can present at any age from early childhood to late adulthood and manifests as a progressive cerebral degeneration. Symptoms are variable, but restricted to the central nervous systems, and include, among others, slowing of cognitive performance, seizures, and movement disorder with a combination of pyramidal, extrapyramidal, and cerebellar features.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some
A rare genetic cerebral small vessel disease characterized by subcortical ischemic events associated with cognitive decline and gait disturbance with an age of onset typically in the sixth or seventh decade of life. Imaging reveals white matter hyperintensities, status cribrosum, lacunar infarcts, and sometimes microbleeds. Extra-neurological manifestations are absent.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some
A rare genetic cerebral small vessel disease characterized by an adult-onset primary microangiopathy with severe atherosclerosis of arterioles and secondary leukoencephalopathy. Patients may present with migraine, transient ischemic attacks, stroke with central facial palsy, cognitive dysfunction with impaired concentration, dementia, depression, movement disorder, vertigo, dysphagia, dysarthria, sicca syndrome, impaired REM sleep, and therapy-resistant hypertension, among others. Brain MRI typically shows a leukoencephalopathy that is disproportionately severe and extensive compared to the clinical disease.	Is a	True	Small vessel cerebrovascular disease (disorder)	Inferred relationship	Some

This concept is not in any reference sets