Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Autoimmune thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
Autoimmune thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Acquired thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
Acquired thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Drug induced thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Drug induced thrombotic thrombocytopenic purpura (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
8 |
Thrombotic thrombocytopenic purpura |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Thrombotic thrombocytopenic purpura |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
6 |
Chronic thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Chronic thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
3 |
Acute intravascular thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Acute intravascular thrombotic microangiopathy |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
3 |
Upshaw-Schulman syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
9 |
Upshaw-Schulman syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
A rare renal disease characterized by thrombotic microangiopathy developing de novo in kidney transplant recipients with no evidence of occurrence of the disease prior to transplantation. Precipitating factors include antibody-mediated rejection, immunosuppressive medication, viral infections, and genetic abnormalities in the complement cascade, among others. The condition most commonly occurs within the first 3-6 months post-transplantation. Clinical presentation is highly variable and ranges from a limited form confined to the kidney with relatively good prognosis to a systemic variant consisting of the classic triad of thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
A rare renal disease characterized by thrombotic microangiopathy developing de novo in kidney transplant recipients with no evidence of occurrence of the disease prior to transplantation. Precipitating factors include antibody-mediated rejection, immunosuppressive medication, viral infections, and genetic abnormalities in the complement cascade, among others. The condition most commonly occurs within the first 3-6 months post-transplantation. Clinical presentation is highly variable and ranges from a limited form confined to the kidney with relatively good prognosis to a systemic variant consisting of the classic triad of thrombocytopenia, microangiopathic hemolytic anemia, and acute kidney injury. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Thrombotic microangiopathy following hemopoietic stem cell transplant (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
1 |
Thrombotic microangiopathy following hemopoietic stem cell transplant (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Hemolytic uremic syndrome, adult type |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
Hemolytic uremic syndrome, adult type |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Hemolytic uremic syndrome of childhood |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Hemolytic uremic syndrome of childhood |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
12 |
Diarrhea-associated hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
12 |
Diarrhea-associated hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
13 |
Diarrhea-negative hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
Diarrhea-negative hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Atypical haemolytic uraemic syndrome |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Atypical haemolytic uraemic syndrome |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
12 |
Congenital hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
4 |
Congenital hemolytic uremic syndrome (disorder) |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Hemolytic uremic syndrome |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
Hemolytic uremic syndrome |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
Haemolytic uraemic syndrome with either a family history of haemolytic uraemic syndrome or a genetic mutation known to cause haemolytic uraemic syndrome, or both. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
2 |
Haemolytic uraemic syndrome with either a family history of haemolytic uraemic syndrome or a genetic mutation known to cause haemolytic uraemic syndrome, or both. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
6 |
A rare genetic hemolytic uremic syndrome (HUS) characterized by infantile onset of relapsing episodes of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The episodes are often preceded by viral infections. Affected individuals typically present persistent hypertension, hematuria, and proteinuria (sometimes in the nephrotic range) and develop chronic kidney disease with age. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
10 |
A rare genetic hemolytic uremic syndrome (HUS) characterized by infantile onset of relapsing episodes of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The episodes are often preceded by viral infections. Affected individuals typically present persistent hypertension, hematuria, and proteinuria (sometimes in the nephrotic range) and develop chronic kidney disease with age. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
A rare type of hemolytic uremic syndrome (HUS) characterized by the triad of hemolytic anemia due to generalized thrombotic microangiopathy, thrombocytopenia, and acute kidney injury, and most commonly occurring after acute gastroenteritis due to Shiga toxin-producing enterohemorrhagic Escherichia coli or Shigella dysenteriae. Other infectious causes of HUS include Streptococcus pneumoniae, HIV, Mycoplasma pneumoniae, Histoplasmosis, and Coxsackie virus. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
11 |
A rare type of hemolytic uremic syndrome (HUS) characterized by the triad of hemolytic anemia due to generalized thrombotic microangiopathy, thrombocytopenia, and acute kidney injury, and most commonly occurring after acute gastroenteritis due to Shiga toxin-producing enterohemorrhagic Escherichia coli or Shigella dysenteriae. Other infectious causes of HUS include Streptococcus pneumoniae, HIV, Mycoplasma pneumoniae, Histoplasmosis, and Coxsackie virus. |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
12 |
Atypical haemolytic uraemic syndrome with complement gene abnormality |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
13 |
Atypical haemolytic uraemic syndrome with complement gene abnormality |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
14 |
Atypical haemolytic uraemic syndrome with anti-factor H antibodies |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
13 |
Atypical haemolytic uraemic syndrome with anti-factor H antibodies |
Associated morphology |
True |
Microthrombus (morphologic abnormality) |
Inferred relationship |
Some |
14 |