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450913003: Mixed phenotype acute leukemia (morphologic abnormality)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2012. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
2920413010 Acute mixed lineage leukaemia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
2920640016 Acute mixed lineage leukemia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
2920793010 Mixed phenotype acute leukaemia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
2921013013 Mixed phenotype acute leukemia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
2921148016 Mixed phenotype acute leukemia (morphologic abnormality) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core


5 descendants. Search Descendants:

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Mixed phenotype acute leukaemia Is a Acute leukemia - category false Inferred relationship Some
Mixed phenotype acute leukaemia Is a Acute leukemia true Inferred relationship Some

Inbound Relationships Type Active Source Characteristic Refinability Group
Acute biphenotypic leukemia Is a True Mixed phenotype acute leukaemia Inferred relationship Some
Mixed phenotype acute leukemia with t(9;22)(q34;q11.2); BCR-ABL1 (morphologic abnormality) Is a True Mixed phenotype acute leukaemia Inferred relationship Some
Mixed phenotype acute leukemia with t(v;11q23); MLL rearranged Is a True Mixed phenotype acute leukaemia Inferred relationship Some
Mixed phenotype acute leukemia with myeloid and B-cell lymphoid phenotypes (morphologic abnormality) Is a True Mixed phenotype acute leukaemia Inferred relationship Some
Mixed phenotype acute leukemia T/myeloid Is a True Mixed phenotype acute leukaemia Inferred relationship Some
A group of rare acute leukemias of ambiguous lineage characterized by the presence of separate populations of blasts of more than one lineage (bilineal), a single population of blasts coexpressing antigens of more than one lineage (biphenotypic), or a combination thereof. The diagnosis relies on immunophenotyping, the T-cell component being characterized by strong expression of cytoplasmic CD3, usually in the absence of surface CD3, the B-cell component expressing CD19, almost always together with CD10, cCD79a, CD22, or PAX5, while the most specific hallmark of the myeloid component is the presence of myeloperoxidase in the blast cytoplasm. Associated morphology True Mixed phenotype acute leukaemia Inferred relationship Some 1

This concept is not in any reference sets

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