46727001: Disorder of zinc metabolism (disorder)

SNOMED CT Concept\Clinical finding (finding)\Disease\Metabolic disease\Disorder of mineral metabolism\Disorder of trace mineral metabolism\Disorder of zinc metabolism

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

77877012 Disorder of zinc metabolism en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

784108011 Disorder of zinc metabolism (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

4542531000241117 trouble du métabolisme du zinc fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Disorder of zinc metabolism	Is a	Disorder of trace mineral metabolism	true	Inferred relationship	Some
Disorder of zinc metabolism	Finding site	Body system structure	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Zinc excess (disorder)	Is a	True	Disorder of zinc metabolism	Inferred relationship	Some
Acquired acrodermatitis enteropathica	Is a	False	Disorder of zinc metabolism	Inferred relationship	Some
Acute zinc deficiency	Is a	False	Disorder of zinc metabolism	Inferred relationship	Some
Hereditary acrodermatitis enteropathica	Is a	True	Disorder of zinc metabolism	Inferred relationship	Some
Chronic zinc deficiency	Is a	True	Disorder of zinc metabolism	Inferred relationship	Some
A rare inborn error of zinc metabolism characterized by recurrent infections, hepatosplenomegaly, anemia (unresponsive to iron supplementation) and chronic systemic inflammation in the presence of high plasma concentrations of zinc and calprotectin. Patients typically present dermal ulcers or other cutaneous manifestations (e.g. inflammation) and arthralgia. Severe epistaxis and spontaneous hematomas have also been reported.	Is a	True	Disorder of zinc metabolism	Inferred relationship	Some
A rare genetic disease characterized by onset of neurological deterioration in the first two years of life, progressing to severe intellectual disability, profound ataxia, mild dyskinesia, axial hypotonia, camptocormia, and oculomotor apraxia. Some patients also develop nephropathy with features of tubulointerstitial nephritis, hypertension, and a tendency for hyperkalemia.	Is a	True	Disorder of zinc metabolism	Inferred relationship	Some

This concept is not in any reference sets