48976006: Prekallikrein deficiency (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Functional finding\Disorder of hemostatic system\Disorders involving the elements of blood coagulation, including platelets, coagulation factors and inhibitors, and the fibrinolytic system.\...

\Contact factor deficiency\Prekallikrein deficiency

\Includes both quantitative and qualitative disorders of procoagulants\Prekallikrein deficiency

\Disease\Disorder of hemostatic system\Disorders involving the elements of blood coagulation, including platelets, coagulation factors and inhibitors, and the fibrinolytic system.\...

\Contact factor deficiency\Prekallikrein deficiency

\Includes both quantitative and qualitative disorders of procoagulants\Prekallikrein deficiency

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

81593014 Prekallikrein deficiency en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

81594015 Fletcher factor deficiency en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

786603018 Prekallikrein deficiency (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1230668019 Fletcher trait en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

4549811000241116 déficit en prékallikréine fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

652081000274111 Präkallikrein-Mangel de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Prekallikrein deficiency	Is a	Contact factor deficiency	true	Inferred relationship	Some
Prekallikrein deficiency	Is a	Includes both quantitative and qualitative disorders of procoagulants	true	Inferred relationship	Some
Prekallikrein deficiency	Finding site	Entire hematological system (body structure)	false	Inferred relationship	Some
Prekallikrein deficiency	Finding site	Body system structure	false	Inferred relationship	Some
Prekallikrein deficiency	Has definitional manifestation	Hemostatic system finding	false	Inferred relationship	Some
Prekallikrein deficiency	Interprets	Hemostatic function	true	Inferred relationship	Some	1
Prekallikrein deficiency	Has interpretation	Abnormal	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Acquired prekallikrein deficiency (disorder)	Is a	True	Prekallikrein deficiency	Inferred relationship	Some
A rare genetic coagulation disorder characterised by the usually incidental laboratory finding of a prolonged activated partial thromboplastin time (aPTT) but normal prothrombin time, due to a deficiency of normal prekallikrein or the presence of nonfunctional prekallikrein. Most patients remain clinically asymptomatic, although an association with cardiovascular conditions (hypertension, myocardial infarction, other coronary artery diseases, and ischaemic strokes) and venous thrombosis, as well as rare cases with increased bleeding tendency have been reported.	Is a	True	Prekallikrein deficiency	Inferred relationship	Some

This concept is not in any reference sets