52967002: Myelofibrosis (disorder)

SNOMED CT Concept\Clinical finding (finding)\Disease\Disorder of body system\Disorder of hematopoietic structure (disorder)\Bone marrow disorder\Myelofibrosis

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

88121017 Myelofibrosis en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

496504011 MF - Myelofibrosis en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

496505012 Myelosclerosis en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

496506013 Agnogenic myeloid metaplasia en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

791034018 Myelofibrosis (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

1874621000195119 mielofibrosi it Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

121171000172110 myélofibrose fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

533141000172112 myelofibrosis fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Myelofibrosis	Is a	Bone marrow disorder	true	Inferred relationship	Some
Myelofibrosis	Finding site	Bone marrow structure	false	Inferred relationship	Some	1
Myelofibrosis	Pathological process	Neoplastic process	false	Inferred relationship	Some
Myelofibrosis	Associated morphology	Reticulin fibrosis	false	Inferred relationship	Some	1
Myelofibrosis	Finding site	Bone structure	false	Inferred relationship	Some
Myelofibrosis	Associated morphology	Reticulin fibrosis	true	Inferred relationship	Some	1
Myelofibrosis	Finding site	Bone marrow structure	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
A rare unclassified acute myeloid leukemia characterized by an acute panmyeloid proliferation with blasts constituting more than 20% of cells in the bone marrow or peripheral blood, accompanied by fibrosis of the bone marrow. Patients typically present with acute onset of severe constitutional symptoms, bone pain, and pancytopenia. Splenomegaly is minimal or absent. The disease is rapidly progressive with poor therapy response.	Is a	True	Myelofibrosis	Inferred relationship	Some
Primary myelofibrosis	Is a	True	Myelofibrosis	Inferred relationship	Some
Ischemic myelofibrosis	Is a	True	Myelofibrosis	Inferred relationship	Some
A rare, genetic, primary immunodeficiency disorder characterized by severe congenital neutropenia, bone marrow fibrosis and neutrophil dysfunction which is refractory to granulocyte colony-stimulating factor, manifesting with life-threatening infections and/or deep-seated abscesses, hepato-/splenomegaly, thrombocytopenia, hypergammaglobulinemia, anemia with reticulocytosis and nephromegaly. Other reported features include osteosclerosis and neurological abnormalities (e.g. developmental delay, cortical blindness, hearing loss, thin corpus callosum or dysrhythmia on EEG).	Is a	True	Myelofibrosis	Inferred relationship	Some
Post-polycythaemia vera myelofibrosis	Is a	True	Myelofibrosis	Inferred relationship	Some
Myelofibrosis due to and following essential thrombocythemia (disorder)	Is a	True	Myelofibrosis	Inferred relationship	Some
Myelofibrosis caused by drug (disorder)	Is a	True	Myelofibrosis	Inferred relationship	Some

Reference Sets