Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Coagulation factor IX variant |
Is a |
True |
Coagulation factor IX |
Inferred relationship |
Some |
|
Coagulation factor IXa |
Is a |
True |
Coagulation factor IX |
Inferred relationship |
Some |
|
Coagulation factor IX antigen |
Direct substance |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Clotting factor IX assay |
Has measured component (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX related antigen measurement |
Has measured component (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Clotting factor IX assay |
Component |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Factor IX related antigen measurement |
Component |
False |
Coagulation factor IX |
Inferred relationship |
Some |
2 |
Product containing high purity factor IX |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
High purity factor IX 250iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
High purity factor IX 500iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
High purity factor IX 1000iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
High purity factor IX 1500iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Recombinant coagulation factor IX (substance) |
Is a |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Product containing factor IX fraction |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Intermediate factor IX |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Product containing anti-inhibitor coagulant complex (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Product containing factor IX concentrate |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Dried factor IX fraction heated 600iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Heat treated human factor IX powder for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX fraction products adverse reaction |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX by-passing fraction products adverse reaction |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX fraction products allergy |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX by-passing fraction products allergy |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX concentrate 500iu powder for injection solution 10mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX concentrate 1000iu powder for injection solution 20mL vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Nonacog alfa (substance) |
Is a |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX complex 100% powder for injection |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Product containing coagulation factor IX (medicinal product) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Factor IX fraction products allergy |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Factor IX by-passing fraction products allergy |
Causative agent (attribute) |
False |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Albutrepenonacog alfa (substance) |
Is a |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Coagulation factor II- and coagulation factor IX- and coagulation factor VIIa- and coagulation factor VIII- and coagulation factor X-containing product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
2 |
Factor VIII by-passing fraction 500iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor VIII by-passing fraction 1000iu powder and solvent for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Dried factor IX fraction heated 600iu powder for conventional release solution for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX 500iu powder for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX 1000iu powder for injection solution vial |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
False |
Coagulation factor IX |
Inferred relationship |
Some |
|
Factor IX adverse reaction |
Causative agent (attribute) |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Coagulation factor II and coagulation factor IX and coagulation factor VIIa and coagulation factor VIII and coagulation factor X only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
2 |
Coagulation factor IX only product |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing only coagulation factor IX in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing coagulation factor IX in parenteral dose form (medicinal product form) |
The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 500 unit/1 vial powder for conventional release solution for injection (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 500 unit/1 vial powder for conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 1000 unit/1 vial powder for conventional release solution for injection (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 1000 unit/1 vial powder for conventional release solution for injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Coagulation factor IX 500 unit powder for solution for infusion vial |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Coagulation factor IX 500 unit powder for solution for infusion vial |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 500 unit/1 vial powder for conventional release solution for infusion and/or injection (clinical drug) |
The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration). |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Product containing precisely coagulation factor IX 500 unit/1 vial powder for conventional release solution for infusion and/or injection (clinical drug) |
This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon. |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |
Factor IX related antigen measurement |
Component |
True |
Coagulation factor IX |
Inferred relationship |
Some |
1 |