57219006: Craniosynostosis syndrome (disorder)

SNOMED CT Concept\Clinical finding (finding)\...

\Head finding (finding)\Cranial suture finding\Imperfect fusion of skull\Craniosynostosis syndrome
\Head finding (finding)\Disorder of head (disorder)\Congenital anomaly of head\Imperfect fusion of skull\Craniosynostosis syndrome

\Musculoskeletal finding\Joint finding\Arthropathy (disorder)\Lesion of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Musculoskeletal finding\Joint finding\Arthropathy (disorder)\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Musculoskeletal finding\Joint finding\Cranial suture finding\Imperfect fusion of skull\Craniosynostosis syndrome
\Musculoskeletal finding\Disorder of musculoskeletal system (disorder)\Disorder of skeletal system\Arthropathy (disorder)\Lesion of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Musculoskeletal finding\Disorder of musculoskeletal system (disorder)\Disorder of skeletal system\Arthropathy (disorder)\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Musculoskeletal finding\Disorder of musculoskeletal system (disorder)\Congenital anomaly of musculoskeletal system\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome

\Disease\Disorder of joint region\Arthropathy (disorder)\Lesion of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Disorder of joint region\Arthropathy (disorder)\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Fetal and/or neonatal disorder\Congenital disease\Congenital malformation\Congenital anomaly of head\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Fetal and/or neonatal disorder\Congenital disease\Congenital malformation\Congenital anomaly of musculoskeletal system\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Disorder of body system\Disorder of musculoskeletal system (disorder)\Disorder of skeletal system\Arthropathy (disorder)\Lesion of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Disorder of body system\Disorder of musculoskeletal system (disorder)\Disorder of skeletal system\Arthropathy (disorder)\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Disorder of body system\Disorder of musculoskeletal system (disorder)\Congenital anomaly of musculoskeletal system\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Disorder of head (disorder)\Congenital anomaly of head\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Developmental disorder\Congenital malformation\Congenital anomaly of head\Imperfect fusion of skull\Craniosynostosis syndrome
\Disease\Developmental disorder\Congenital malformation\Congenital anomaly of musculoskeletal system\Congenital anomaly of joint\Imperfect fusion of skull\Craniosynostosis syndrome

Status: current, Sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2019. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Craniosynostosis syndrome	Is a	Congenital anomaly of joint	false	Inferred relationship	Some
Craniosynostosis syndrome	Is a	Congenital abnormality of skull and face bones	false	Inferred relationship	Some
Craniosynostosis syndrome	Occurrence	Congenital	false	Inferred relationship	Some
Craniosynostosis syndrome	Finding site	Joint structure of suture of skull	true	Inferred relationship	Some	1
Craniosynostosis syndrome	Associated morphology	anomalie congénitale	false	Inferred relationship	Some	1
Craniosynostosis syndrome	Is a	Congenital anomaly of bone and joint	false	Inferred relationship	Some
Craniosynostosis syndrome	Is a	Cranial suture finding	false	Inferred relationship	Some
Craniosynostosis syndrome	Associated morphology	anomalie congénitale	false	Inferred relationship	Some	2
Craniosynostosis syndrome	Finding site	Bone structure of cranium	false	Inferred relationship	Some	2
Craniosynostosis syndrome	Is a	Congenital malformation	false	Inferred relationship	Some
Craniosynostosis syndrome	Associated morphology	Congenital premature fusion	false	Inferred relationship	Some	1
Craniosynostosis syndrome	Finding site	Joint structure of suture of skull	false	Inferred relationship	Some	1
Craniosynostosis syndrome	Finding site	Bone structure of cranium	false	Inferred relationship	Some
Craniosynostosis syndrome	Associated morphology	anomalie congénitale	false	Inferred relationship	Some	2
Craniosynostosis syndrome	Finding site	Joint structure of suture of skull	false	Inferred relationship	Some	1
Craniosynostosis syndrome	Associated morphology	Congenital premature fusion	false	Inferred relationship	Some	1
Craniosynostosis syndrome	Occurrence	Congenital	false	Inferred relationship	Some	3
Craniosynostosis syndrome	Is a	Congenital anomaly of head	false	Inferred relationship	Some
Craniosynostosis syndrome	Is a	Congenital anomaly of joint	false	Inferred relationship	Some
Craniosynostosis syndrome	Associated morphology	Congenital premature fusion	false	Inferred relationship	Some	3
Craniosynostosis syndrome	Finding site	Joint structure of suture of skull	false	Inferred relationship	Some	3
Craniosynostosis syndrome	Is a	Disorder of skull (disorder)	false	Inferred relationship	Some
Craniosynostosis syndrome	Is a	Lesion of joint	false	Inferred relationship	Some
Craniosynostosis syndrome	Is a	Imperfect fusion of skull	true	Inferred relationship	Some
Craniosynostosis syndrome	Occurrence	Congenital	true	Inferred relationship	Some	1
Craniosynostosis syndrome	Pathological process (attribute)	Pathological developmental process	true	Inferred relationship	Some	1
Craniosynostosis syndrome	Associated morphology	Premature fusion	true	Inferred relationship	Some	1

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Interfrontal craniofaciosynostosis	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Fronto-parietal craniofaciosynostosis	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Fronto-malar faciosynostosis	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Parieto-occipital craniosynostosis	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Interparietal craniosynostosis (disorder)	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Unicoronal craniosynostosis	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Bicoronal craniosynostosis	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Cloverleaf skull syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Schprintzen	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Crouzon disease is characterised by craniosynostosis and facial hypoplasia.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Antley-Bixler syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Apert's syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Acrocephalosyndactyly type V (disorder)	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Baller-Gerold syndrome	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Saethre-Chotzen syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Fibroblast growth factor receptor 3-related craniosynostosis (disorder)	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Acrocephalosyndactyly type I	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Acrocephaly	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Carpenter's syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Cutis gyrata syndrome of Beare and Stevenson	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Nonsyndromic premature fusion of multiple sutures.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Nonsyndromic premature fusion of a single suture.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Acrocephalosyndactyly	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Jackson-Weiss syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
An abnormally high skull with shortness of anterior-posterior dimension. A type of craniosynostosis in which there is premature closure of the coronal suture resulting in an abnormally short anteroposterior diameter of the cranium.	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Holoprosencephaly craniosynostosis syndrome (disorder)	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Pseudoaminopterin syndrome is a developmental anomalies syndrome that resembles the aminopterin embryopathy without history of fetal exposure to aminopterin. It is characterized by skull (craniosynostosis and poorly mineralized cranial vault), dysmorphic (ocular hypertelorism, palpebral fissure anomalies, micrognathia cleft lip and/or high arched palate and small and low set/rotated ears) and limb (brachydactyly, syndactyly and clinodactyly) anomalies, associated with mild-to-moderate intellectual deficit and short stature.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Spondyloepiphyseal dysplasia Nishimura type is characterized by spondyloepiphyseal dysplasia, craniosynostosis, cataracts, cleft palate and intellectual deficit.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare genetic disorder characterized by craniosynostosis, craniofacial and skeletal abnormalities, marfanoid habitus, cardiac anomalies, neurological abnormalities, and intellectual disability.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare, multiple congenital anomalies syndrome with intellectual disability commonly characterized by facial dysmorphism (e.g. sagittal craniosynostosis, hypertelorism, strabismus, low-set dysplastic ears, retrognathia or micrognathia, mandibular ankyloses, cleft palate, aplasia uvulae), congenital heart defects (e.g. atrioventricular septal defect, anomalous venous return), genital anomalies (e.g. cryptorchidism, microphallus), as well as growth delay and intellectual disability. In some cases, tracheobronchial anomalies, large joint contractures, syndactyly, rib anomalies and hypoplastic kidneys are reported. Rarely, no cardiac anomaly may be reported.	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
A rare cranial malformation syndrome characterized by the premature closure of both lambdoid sutures and the posterior sagittal suture, resulting in abnormal skull contour (frontal bossing, anterior turricephaly with mild brachycephaly, biparietal narrowing, occipital concavity) and dysmorphic facial features (low-set ears, midfacial hypoplasia). Short stature, developmental delay, epilepsy, and oculomotor dyspraxia have also been reported. Associated anomalies include enlargement of the cerebral ventricles, agenesis of the corpus callosum, Arnold-Chiari malformation type I, venous anomalies of skull, and hydrocephalus.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis - anal anomalies - porokeratosis, or CDAGS, is a very rare condition characterized by craniosynostosis and clavicular hypoplasia, (C), delayed closure of the fontanel (D), anal anomalies (A), genitourinary malformations (G) and skin eruption (S).	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare malformation disorder characterized by sagittal craniosynostosis, Dandy-Walker malformation, hydrocephalus, craniofacial dysmorphism (including dolichocephaly, hypertelorism, micrognathia, positional ear deformity) and variable developmental delay.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis with facial dysmorphism and brachydactyly syndrome	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
A rare syndromic craniosynostosis characterized by sagittal craniosynostosis, hydrocephalus, Chiari I malformation and radioulnar synostosis. Other clinical findings include blepharophimosis, small low-set ears, hypoplastic philtrum, kidney malformation, and hypogenitalism.	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis-intracranial calcifications syndrome is a form of syndromic craniosynostosis characterized by pancraniosynostosis, head circumference below the mid-parental head circumference, mild facial dysmorphism (prominent supraorbital ridges, mild proptosis and maxillary hypoplasia) and calcification of the basal ganglia. The disease is associated with a favorable neurological outcome, normal intelligence and is inherited in an autosomal recessive manner.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis, Boston type is a form of syndromic craniosynostosis, characterized by a highly variable craniosynostosis with frontal bossing, turribrachycephaly and cloverleaf skull anomaly. Hypoplasia of the supraorbital ridges, cleft palate, extra teeth and limb anomalies (triphalangeal thumb, 3-4 syndactyly of the hands, a short first metatarsal, middle phalangeal agenesis in the feet) have also been described. Associated problems include headache, poor vision, and seizures. Intelligence is normal.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Hunter-McAlpine craniosynostosis is characterized by craniosynostosis, intellectual deficit, short stature, facial dysmorphism (oval face with almond-shaped palpebral fissures, droopy eyelids and a small nose) and minor distal anomalies. It has been described in 10 patients. Transmission is autosomal dominant and the syndrome is associated with partial duplication of the long arm of chromosome 5 (5q35-5qter).	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Lowry-MacLean syndrome is a very rare syndrome characterized by microcephaly, craniosynostosis, glaucoma, growth failure and visceral malformations.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Obesity-colitis-hypothyroidism-cardiac hypertrophy-developmental delay syndrome is characterized by precocious obesity, congenital hypothyroidism, neonatal colitis, cardiac hypertrophy, craniosynostosis and developmental delay. It has been described in two brothers, one of whom died within the first month of life. The parents of the two children were nonconsanguineous and in good health, however, the pregnancies were complicated by a maternal HELLP syndrome (Haemolysis, Elevated Liver enzymes and Low Platelets). The mode of inheritance has not yet been clearly established.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare syndromic agammaglobulinaemia characterised by profound B-cell depletion (with normal T-cell numbers) resulting in agammaglobulinaemia, associated with severe developmental delay, microcephaly, craniosynostosis, cleft palate, narrowing of the choanae, blepharophimosis, and severe dermatitis. Additional reported features include distal joint contractures, renal/genitourinary anomalies, and mild cerebral atrophy, among others.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Familial scaphocephaly syndrome, McGillivray type is a rare newly described craniosynostosis syndrome characterized by scaphocephaly, macrocephaly, severe maxillary retrusion, and mild intellectual disability.	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
A rare syndromic craniosynostosis malformation syndrome characterized by intrauterine growth retardation, under ossification of the skull with large fontanels, short limbs with absent phalanges, and finger and toe syndactyly. Reported dysmorphic features include a narrow face with small palpebral fissures, small, pointed nose, microstomia, micrognathia, and low-set and posteriorly rotated ears. A posterior encephalocele and other congenital malformations can also be observed.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis fibular aplasia syndrome (disorder)	Is a	False	Craniosynostosis syndrome	Inferred relationship	Some
A rare multiple congenital anomalies syndrome characterised by variable skeletal abnormalities (including craniostenosis, pectus carinatum, short sternum, joint hyperextensibility, and abnormal vertebrae), cutis laxa with excessive skin folds around the cheek, chin and neck, ambiguous genitalia with a micropenis and perineal hypospadia, an umbilical hernia, intellectual disability, premature aged appearance, and cardiac enlargement involving either the ventricles or atria. Facial dysmorphism is variable and can include multiple hair whorls, ptosis, high and broad nasal root, low set ears and small chin. Enamel hypocalcification, abnormal modelling of tubular bones, and reduced cutis laxa may become apparent later on.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis, Herrmann-Opitz type is a rare bone development disorder characterized by intellectual disability, short stature, turribrachycephaly, facial dysmorphism (i.e. severe hypertelorism, hypoplasia of supraorbital ridges, abnormal ears, and micrognathia), bony defects of the occiput, and digital anomalies (including syndactyly, oligodactyly, and/or brachydactyly). Urethral atresia has also been reported. There have been no further descriptions in the literature since 1987.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare syndromic craniosynostosis characterized by premature fusion of multiple or all calvarial sutures (resulting in variable abnormal shape of the head), midface hypoplasia, delayed and ectopic tooth eruption and supernumerary teeth. Associated facial dysmorphism includes proptosis, hypertelorism, beaked nose, and relative prognathism. Variable digital anomalies (e.g. finger and/or toe syndactyly, clinodactyly), short stature, cognitive and/or motor delay, high palate, ear deformity and conductive hearing loss have also been reported.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Lethal occipital encephalocele-skeletal dysplasia syndrome is a rare, genetic, bone development disorder characterized by occipital and parietal bone hypoplasia leading to occipital encephalocele, calvarial mineralization defects, craniosynostosis, radiohumeral fusions, oligodactyly and other skeletal anomalies (arachnodactyly, terminal phalangeal aplasia of the thumbs, bilateral absence of the great toes, pronounced bilateral angulation of femora, shortened limbs, advanced osseous maturation). Fetal death in utero is associated.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
FGFR2-related bent bone dysplasia is a rare, genetic, lethal, primary bone dysplasia characterized by dysmorphic craniofacial features (low-set, posteriorly rotated ears, hypertelorism, megalophthalmos, flattened and hypoplastic midface, micrognathia), hypomineralization of the calvarium, craniosynostosis, hypoplastic clavicles and pubis, and bent long bones (particularly involving the femora), caused by germline mutations in the FGFR2 gene. Prematurely erupted fetal teeth, osteopenia, hirsutism, clitoromegaly, gingival hyperplasia, and hepatosplenomegaly with extramedullary hematopoiesis may also be associated.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Trigonocephaly	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare frontonasal dysplasia malformation syndrome characterised by an oxycephalic skull with craniosynostosis, wide nose with anteverted nostrils, hirsutism at base of nose, agenesis of the nasolacrimal ducts, and bilateral, symmetrical nasolabial cysts on upper lip. Additional features may include hypertelorism. There have been no further descriptions in the literature since 1991.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Long narrow head	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A polymalformative syndrome characterized by craniosynostosis, Poland anomaly, cranio-fronto-nasal dysplasia, and genital and breast anomalies.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Craniosynostosis, Philadelphia type is a form of syndromic craniosynostosis, characterized by sagittal/dolichocephalic head shape with a relatively normal facial appearance and complete soft tissue syndactyly of hand and foot. Transmission is autosomal dominant with variable expression of the hand findings, and incomplete penetrance of the sagittal craniosynostosis. Craniosynostosis, Philadelphia type has been suggested to share the same etiology as syndactyly type 1A.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Curry-Jones syndrome is a form of syndromic craniosynostosis characterized by unilateral coronal craniosynostosis or multiple suture synostosis associated with complete or partial agenesis of the corpus callosum, preaxial polysyndactyly and syndactyly of hands and/or feet, along with anomalies of the skin (characteristic pearly white areas that become scarred and atrophic, abnormal hair growth around the eyes and/or cheeks, and on the limbs), eyes (iris colobomas, microphthalmia,) and intestine (congenital short gut, malrotation, dysmotility, chronic constipation, bleeding and myofibromas). Developmental delay and variable degrees of intellectual disability may also be observed. Multiple intra-abdominal smooth muscle hamartomas, trichoblastoma of the skin, occipital meningoceles and development of desmoplastic medulloblastoma have been reported.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare genetic multiple congenital anomalies/dysmorphic syndrome with variable intellectual disability characterized by abnormal head shape/metopic ridging and facial dysmorphism (which may include arched eyebrows, ptosis, downslanting palpebral fissures, epicanthal folds, and short upturned nose). Many patients present variable global developmental delay and/or autism spectrum disorder. Additional reported features are cardiac, skeletal, or urogenital anomalies. Brain imaging may show agenesis of the corpus callosum.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
A rare genetic multiple congenital anomalies/dysmorphic syndrome characterized by developmental delay, moderate to severe intellectual disability, dysmorphic features including craniosynostosis, micro-/retrognathia, cleft palate, and brachydactyly, and short stature. Seizures, skeletal anomalies (such as arthrogryposis, gracile bones, and pathological fractures), and renal abnormalities have also been described. Cerebral MRI may show periventricular white matter changes and ventriculomegaly.	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some
Congenital synostosis of coronal suture of skull	Is a	True	Craniosynostosis syndrome	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
95171016	Craniosynostosis syndrome	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95172011	Craniostosis	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95173018	Craniosynostosis	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95174012	Premature closure of cranial sutures	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95175013	Congenital ossification of cranial sutures	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95176014	Congenital ossification of sutures of skull	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
95177017	Craniostenosis	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
795817015	Craniosynostosis syndrome (disorder)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1231700010	CSO - Craniosynostosis	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
1231701014	Premature cranial suture closure	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1820311000195114	sindrome da craniosinostosi	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
88261000172117	craniosténose	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
466731000172113	syndrome de craniosynostose	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
506041000172111	craniosynostose	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3381001001000110	Kraniosynostose	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module