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60436000: Axon structure (cell structure)

SNOMED CT Concept\Body structure (body structure)\Anatomical or acquired body structure (body structure)\Anatomical structure\...

\An anatomical structure that consists of the maximal set of organ parts so connected to one another that together they constitute a self-contained unit of macroscopic anatomy, distinct both morphologically and functionally from other such units. Together with other organs, an organ constitutes an organ system or a body part. An organ is divisible into organ parts but not organs (examples: femur, biceps, liver, heart, aorta, sciatic nerve, ovary).\Brain and spinal cord structure (body structure)\White matter structure of brain and spinal cord (body structure)\Central nervous system tract structure\Axon structure

\Body tissue structure\Structure of nervous tissue (body structure)\Central nervous tissue\White matter structure of brain and spinal cord (body structure)\Central nervous system tract structure\Axon structure

\Cell\Subcellular structure\Axon structure

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

100422019 Axon en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

498737018 Axon structure en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

1203934013 Axon structure (cell structure) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Axon structure	Is a	Subcellular structure	true	Inferred relationship	Some
Axon structure	Is a	Central nervous system tract structure	true	Inferred relationship	Some
Axon structure	partie de	Neuron (cell)	false	Additional relationship	Some
Axon structure	partie de	Entire central nervous system tract	false	Additional relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Axon hillock	Is a	True	Axon structure	Inferred relationship	Some
Entire axon	Is a	True	Axon structure	Inferred relationship	Some
Peripheral nerve axis cylinder	Is a	True	Axon structure	Inferred relationship	Some
Central nervous system axis cylinder	Is a	True	Axon structure	Inferred relationship	Some
Giant axonal neuropathy (GAN) is a severe, slowly progressive neurodegenerative disorder characterised by progressive motor and sensory peripheral neuropathy, central nervous system involvement (including pyramidal and cerebellar signs), and characteristic kinky hair in most cases.	Finding site	False	Axon structure	Inferred relationship	Some
Dying back phenomenon	Finding site	False	Axon structure	Inferred relationship	Some	1
Dying back phenomenon	Finding site	False	Axon structure	Inferred relationship	Some	1
Ranvier's node	Is a	True	Axon structure	Inferred relationship	Some
Axonal neuropathy	Finding site	True	Axon structure	Inferred relationship	Some	2
Giant axonal neuropathy (GAN) is a severe, slowly progressive neurodegenerative disorder characterised by progressive motor and sensory peripheral neuropathy, central nervous system involvement (including pyramidal and cerebellar signs), and characteristic kinky hair in most cases.	Finding site	True	Axon structure	Inferred relationship	Some	2
Axonal sensorimotor neuropathy	Finding site	True	Axon structure	Inferred relationship	Some	2
A rare syndromic neurological disorder characterized by the association of Möbius syndrome (congenital facial palsy with impaired ocular abduction) with peripheral axonal neuropathy and hypogonadotropic hypogonadism. There have been no further reports since 1996.	Finding site	True	Axon structure	Inferred relationship	Some	1
Peripheral axonal neuropathy	Finding site	True	Axon structure	Inferred relationship	Some	2
Autosomal recessive axonal neuropathy with neuromyotonia	Finding site	True	Axon structure	Inferred relationship	Some	2
A rare mitochondrial disease characterized by signs and symptoms within a phenotypic and metabolic spectrum that includes global developmental delay, hypotonia, intellectual disability, optic atrophy, axonal neuropathy, hypertrophic cardiomyopathy, lactic acidosis, and increased excretion of Krebs cycle intermediates. Other variable features are spasticity, seizures, ataxia, congenital cataract, and dysmorphic facial features. Age of onset is in the neonatal period or infancy.	Finding site	True	Axon structure	Inferred relationship	Some	3
A rare, genetic, autosomal recessive axonal hereditary motor and sensory neuropathy disease characterized by prenatal onset of a severe sensorimotor axonal polyneuropathy (reflected by reduced fetal movement and polyhydramnios), manifesting, at birth, with respiratory failure requiring mechanical ventilation, profound muscular hypotonia, rapidly progressing distal muscle weakness, and absent deep tendon reflexes, in the absence of contractures, leading to death before 8 months of age. Neuropathological findings show severe loss of large- and medium-sized myelinated fibers without signs of demyelination.	Finding site	True	Axon structure	Inferred relationship	Some	5
A rare, congenital, autosomal recessive axonal hereditary motor and sensory neuropathy disease characterized by axonal neuropathy, manifesting at birth or shortly thereafter with generalized muscular hypotonia, prominently distal muscular weakness, respiratory/swallowing difficulties and diffuse areflexia, associated with central nervous system involvement, which includes progressive microcephaly, seizures, and global developmental delay. Additional variable manifestations include hearing impairment, ocular lesions, skeletal anomalies (e.g. talipes equinovarus, overriding toes, scoliosis, joint contractures), cryptorchidism, and dysmorphic features (such as coarse facies, hypertelorism, high-arched palate). Outcome is typically poor due to respiratory insufficiency and/or aspiration pneumonia.	Finding site	True	Axon structure	Inferred relationship	Some	3
A rare neurologic disease characterized by axonal sensorimotor neuropathy, progressive optic atrophy, cognitive deficit, bulbar dysfunction, seizures, and early hypotonia and feeding difficulties. Additional possible features include dystonia, scoliosis, joint contractures, ocular anomalies, and urogenital anomalies. Brain MRI reveals variable degrees of cerebral atrophy. The disease is fatal in childhood due to respiratory failure.	Finding site	True	Axon structure	Inferred relationship	Some	6
Atrophy of axon of peripheral nerve structure (disorder)	Finding site	True	Axon structure	Inferred relationship	Some	1

Reference Sets

Anatomy structure and entire association reference set (foundation metadata concept)

Back to Start

Id	Description	Lang	Type	Status	Case?	Module
100422019	Axon	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
498737018	Axon structure	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1203934013	Axon structure (cell structure)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core