6445007: Mast cell (cell)

SNOMED CT Concept\Body structure (body structure)\Anatomical or acquired body structure (body structure)\Anatomical structure\...

\Body system structure\Structure of hematological system (body structure)\Blood cell\Leukocyte\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)
\Body system structure\Structure of hematological system (body structure)\Hematopoietic system structure\Mononuclear phagocyte system structure (body structure)\Reticuloendothelial cell\Mononuclear cell (histiocyte, lymphocyte, plasma cell)\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)
\Body system structure\Structure of immune system (body structure)\Mononuclear phagocyte system structure (body structure)\Reticuloendothelial cell\Mononuclear cell (histiocyte, lymphocyte, plasma cell)\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)
\Body system structure\Structure of immune system (body structure)\Leukocyte\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)

\Cell\Entire cell\...

\Phagocytic cell\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)

\Immunologic cell\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)

\Blood cell\Leukocyte\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)

\Reticuloendothelial cell\Mononuclear cell (histiocyte, lymphocyte, plasma cell)\Peripheral blood mononuclear cell (cell)\Monocyte\Macrophage\Resident tissue macrophage (cell)\Mast cell (cell)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Mast cell (cell)	Is a	Cell	false	Inferred relationship	Some
Mast cell (cell)	partie de	Connective tissue structure	false	Inferred relationship	Some
Mast cell (cell)	Is a	Entire cell	false	Inferred relationship	Some
Mast cell (cell)	Is a	Resident tissue macrophage (cell)	true	Inferred relationship	Some
Mast cell (cell)	partie de	Structure of myelopoietic tissue	false	Additional relationship	Some
Mast cell (cell)	partie de	Mononuclear phagocyte system structure (body structure)	false	Additional relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Reactive mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Histiocytic and mast cell tumor of uncertain behavior	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
Mast cell leukaemia (clinical)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	1
Progressive systemic mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Cutaneous mastocytosis, adult form (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Urticaria pigmentosa, diffuse erythrodermic type	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Urticaria pigmentosa, multiple nodules AND/OR plaques	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Localized extracutaneous mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Urticaria pigmentosa, telangiectasia macularis eruptiva perstans	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Indolent systemic mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Non malignant mast cell disease	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Cutaneous mastocytosis, infantile form (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some
urticaire pigmentaire	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Urticaria pigmentosa, maculopapular type	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Urticaria pigmentosa, solitary cutaneous nodule	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Malignant mast cell tumors	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Neoplasm of uncertain behavior of histiocytic and mast cells	Finding site	False	Mast cell (cell)	Inferred relationship	Some
Reactive mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Mast cell leukaemia (clinical)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor (clinical)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumors	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of lymph nodes of head and neck (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of intrathoracic lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of intra-abdominal lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of lymph nodes of axilla and upper limb	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of lymph nodes of inguinal region and lower limb	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of intrapelvic lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell sarcoma of spleen (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
Mast cell malignancy of lymph nodes of multiple sites	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell activation syndrome (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
Idiopathic anaphylaxis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Cutaneous mastocytosis, adult form (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Bullous cutaneous mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Mast cell leukemia affecting skin (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell disorder (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
Aggressive lymphadenopathic mastocytosis with eosinophilia (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell malignancy of lymph nodes (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Diffuse erythrodermic mastocytosis (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	4
Systemic mast cell disease (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	1
Mast cell malignancy (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	1
Solitary cutaneous mastocytoma (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Familial mastocytosis (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Cutaneous mastocytosis (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	4
Indolent systemic mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some	4
Indolent systemic mastocytosis	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Localized extracutaneous mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	2
Non malignant mast cell disease	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
A rare multiple congenital anomalies syndrome characterized by cutaneous mastocytosis, microcephaly, microtia and/or hearing loss, hypotonia and skeletal anomalies (e.g. clinodactyly, camptodactyly, scoliosis). Additional common features are short stature, intellectual disability and difficulties. Facial dysmorphism may include upslanted palpebral fissures, highly arched palate and micrognathia. Rarely, seizures and asymmetrically small feet have been reported.	Finding site	False	Mast cell (cell)	Inferred relationship	Some	6
A rare, aggressive form of advanced systemic mastocytosis (advSM) characterized by massive infiltration of mast cells (MC) in different tissues and presence of extracutaneous organ dysfunction, but without evidence of mast cell leukemia or another hematologic neoplasm.	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
leucémie mastocytaire classique	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Cutaneous mastocytosis, infantile form (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
leucémie mastocytaire aleucémique	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of intra-abdominal lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of intrapelvic lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of intrathoracic lymph nodes	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of lymph nodes of axilla AND/OR upper limb	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of lymph nodes of head, face AND/OR neck	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of lymph nodes of inguinal region AND/OR lower limb	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of lymph nodes of multiple sites	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of spleen	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Malignant mast cell tumor of extranodal AND/OR solid organ site	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Telangiectasia macularis eruptiva perstans	Finding site	True	Mast cell (cell)	Inferred relationship	Some	4
urticaire pigmentaire	Finding site	False	Mast cell (cell)	Inferred relationship	Some	3
Mast cell gastritis (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
Aggressive lymphadenopathic mastocytosis with eosinophilia (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease (disorder)	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
A rare, aggressive form of advanced systemic mastocytosis (advSM) characterized by massive infiltration of mast cells (MC) in different tissues and presence of extracutaneous organ dysfunction, but without evidence of mast cell leukemia or another hematologic neoplasm.	Finding site	False	Mast cell (cell)	Inferred relationship	Some	1
leucémie mastocytaire aleucémique	Finding site	False	Mast cell (cell)	Inferred relationship	Some	2
Reactive mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
A rare multiple congenital anomalies syndrome characterized by cutaneous mastocytosis, microcephaly, microtia and/or hearing loss, hypotonia and skeletal anomalies (e.g. clinodactyly, camptodactyly, scoliosis). Additional common features are short stature, intellectual disability and difficulties. Facial dysmorphism may include upslanted palpebral fissures, highly arched palate and micrognathia. Rarely, seizures and asymmetrically small feet have been reported.	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
Bullous diffuse cutaneous mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	4
Idiopathic mast cell activation syndrome (disorder)	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
Pseudoxanthomatous nodular cutaneous mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
A rare hematologic disease characterized by symptoms of mast cell activation in the absence of cutaneous findings, as well as absence of diagnostic criteria of systemic mastocytosis with tryptase levels of less than 20 ng/ml and normal to low burden of mast cells. Bone marrow biopsy reveals the presence of monoclonal mast cells carrying the KIT D816V mutation and/or expressing CD25. Patients present with recurrent episodes of flushing, headache, hypotension, abdominal cramping, nausea, diarrhea, cardiac arrhythmias, bronchoconstriction, and bleeding diathesis, among others.	Finding site	True	Mast cell (cell)	Inferred relationship	Some	3
Congenital cutaneous mastocytosis	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1
A form of cutaneous mastocytosis (CM) characterised by the presence of multiple hyperpigmented macules, papules or nodules associated with abnormal accumulation of mast cells in the skin. Most patients present in infancy or childhood, but onset may also occur in adulthood. Mutations in the KIT gene (4q11-q12) have been identified however this mutation is rare in the paediatric population and the aetiology and pathogenesis in these cases remains to be determined. The disease generally occurs sporadically but rare familial cases have been reported.	Finding site	True	Mast cell (cell)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
11689015	Mast cell	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
11690012	Tissue basophil	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
11691011	Basophilic histiocyte	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
11692016	Mastocyte	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
1204117014	Mast cell (cell)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core