Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Oesophageal anastomotic necrosis |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Necrosis of anatomical site |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Tuberculous osteonecrosis |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis following injection of local anaesthetic |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Necrosis of sacral muscle co-occurrent and due to chronic ulcer of sacrum (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Avascular necrosis of sacral bone due to chronic ulcer of sacrum (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
4 |
Necrosis of bone of buttock co-occurrent and due to chronic ulcer of buttock |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of back bone co-occurrent and due to chronic ulcer of back |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Osteonecrosis of ankle bone due to chronic ulcer of ankle |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of muscle of buttock co-occurrent and due to chronic ulcer of buttock (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of ankle muscle co-occurrent and due to chronic ulcer of ankle (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Osteonecrosis due to hemoglobinopathy |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of jaw caused by bisphosphonate |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Osteonecrosis caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of hand due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of tibia due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
ostéonécrose due à un traumatisme |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of shoulder due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of femur due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of fibula due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of toe due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of finger due to trauma |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of carpus caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of femur caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of tibia caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of pelvis caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of toe caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of shoulder caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of hand caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of ankle caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of fibula caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of radius caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of jaw caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis of finger caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Avascular necrosis of fibula due to chronic ulcer of calf (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
4 |
Necrosis of calf muscle co-occurrent and due to chronic ulcer of calf (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Infected pancreatic necrosis (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Anaerobic myonecrosis |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Acute pyelonephritis with medullary necrosis |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
5 |
Toxic epidermal necrolysis caused by drug |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of lower leg muscle co-occurrent and due to chronic ulcer of lower leg |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Avascular necrosis of bone of lower leg due to chronic ulcer of lower extremity (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of skin flap (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of flap (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Necrosis of ankle muscle co-occurrent and due to chronic ulcer of ankle (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Necrotizing herpetic retinopathy |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Necrosis of muscle of buttock co-occurrent and due to chronic ulcer of buttock (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Renal papillary necrosis in a patient with a long history of regular analgesic drug use. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
A rare lethal combination of manifestations including short stature, congenital cataracts, encephalopathy with epileptic fits, and postmortem confirmation of nephropathy (renal tubular necrosis). There have been no further descriptions in the literature since 1963. |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Renal papillary necrosis in a patient with sickle cell disease or sickle cell trait. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Renal papillary necrosis in a patient with type 1 or type 2 diabetes. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Necrosis of capillary of kidney due to glomerular disease (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
A life-threatening, rapidly progressive thrombotic disorder affecting mainly neonates and children that is characterized by purpuric skin lesions and disseminated intravascular coagulation. It may progress rapidly to multi-organ failure caused by thrombotic occlusion of small and medium-sized blood vessels. There are two forms of the disorder that are classified according to triggering mechanisms: acute infectious (the most common form), and idiopathic purpura fulminans. |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
6 |
Osteonecrosis due to and following renal dialysis |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of skin due to and following injection of filler (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Necrosis of myocutaneous flap (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Stevens-Johnson and toxic epidermal necrolysis overlap syndrome caused by drug (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
12 |
Drug-induced Stevens-Johnson syndrome |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Assessment of necrosis of skin (procedure) |
Procedure morphology (attribute) |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Severe mucocutaneous reactions; skin detachment of 10 to 30 percent of body surface area most commonly triggered by medications, characterised by extensive necrosis and detachment of the epidermis. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
A limited form of Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum characterised by destruction and detachment of the skin epithelium, involving less than 10% of the body surface area, and mucous membranes. Onset usually occurs 4-28 days after administration of the causal medication and is most frequently associated with anticonvulsants, antibacterial sulfonamides, allopurinol, nevirapine, and oxicams (non-steroidal anti-inflammatory drugs), but many other medications have also been implicated. The disease is not induced by medication in 15% of cases. Histology is characterised by an epidermal necrolysis. Multiple disabling long-term sequelae (especially cutaneous, ocular and psychological) are frequent. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Osteonecrosis caused by ionizing radiation |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Bilateral osteonecrosis of femurs caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
3 |
Bilateral osteonecrosis of femurs caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
4 |
Neonatal ecthyma gangrenosum (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Ecthyma gangrenosum |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
5 |
Necrolytic acral erythema (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
An extended form of toxic epidermal necrolysis with characteristics of destruction and detachment of the skin epithelium and mucous membranes involving more than 30% of the body surface area. Lyell syndrome can be triggered by a drug allergy and, exceptionally, by infections or bone marrow transplantation. In 25 to 30% of cases, the cause is unclear. Patients should be admitted to an intensive care or burns unit as soon as the diagnosis is suspected. Prognosis is poor (mortality rate: 20-25%). |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
A rare toxic dermatosis with clinical and histological features characterized by the destruction and detachment of the skin epithelium and mucous membranes. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Toxic epidermal necrolysis due to graft-versus-host disease (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Lyell syndrome due to infection (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Progressive polyneuropathy with bilateral striatal necrosis is a rare, genetic disorder of thiamine metabolism and transport characterized by the childhood-onset of recurrent episodes of flaccid paralysis and encephalopathy, associated with bilateral striatal necrosis and chronic progressive axonal polyneuropathy with proximal and distal muscle weakness, areflexia, contractures and foot deformities. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Tissue necrosis of upper arm due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of knee and lower leg due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of ankle and foot due to and following frostbite |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Tissue necrosis of multiple body regions due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Tissue necrosis due to and following frostbite |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of neck due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of upper limb due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Tissue necrosis of knee and lower leg due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Tissue necrosis of hip and thigh due to and following frostbite |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Tissue necrosis of thorax due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of abdominal wall, lower back and pelvis due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Frostbite with tissue necrosis of head |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Tissue necrosis of abdominal wall, lower back and pelvis due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
5 |
Tissue necrosis of abdominal wall, lower back and pelvis due to and following frostbite (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
3 |
Tissue necrosis of wrist and hand due to and following frostbite (disorder) |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of ankle and foot due to and following frostbite |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Tissue necrosis of hip and thigh due to and following frostbite |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
A rare lethal combination of manifestations including short stature, congenital cataracts, encephalopathy with epileptic fits, and postmortem confirmation of nephropathy (renal tubular necrosis). There have been no further descriptions in the literature since 1963. |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Surgical wound necrosis (finding) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Glaukomflecken |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Necrosis of amputation stump of left lower limb (disorder) |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Necrosis of amputation stump of right lower limb |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
1 |
Bronchial anastomotic necrosis |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Gastrointestinal anastomotic necrosis |
Associated morphology |
True |
Necrosis |
Inferred relationship |
Some |
2 |
Osteonecrosis caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Osteonecrosis of ankle caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Osteonecrosis of femur caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Osteonecrosis of fibula caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |
Osteonecrosis of hand caused by drug |
Associated morphology |
False |
Necrosis |
Inferred relationship |
Some |
1 |