66384003: Isophane insulin (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with molecular messenger mechanism of action (substance)\Hormone\...

\Pancreatic hormone\Insulin\Isophane insulin

\Polypeptide hormone\Insulin\Isophane insulin

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Hormone\...

\Pancreatic hormone\Insulin\Isophane insulin

\Polypeptide hormone\Insulin\Isophane insulin

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\...

\Polypeptide\Protein\Protamine and/or protamine derivative (substance)\Isophane insulin
\Polypeptide\Polypeptide hormone\Insulin\Isophane insulin

\Pancreatic hormone\Insulin\Isophane insulin

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\...

\Polypeptide\Protein\Protamine and/or protamine derivative (substance)\Isophane insulin
\Polypeptide\Polypeptide hormone\Insulin\Isophane insulin

\Pancreatic hormone\Insulin\Isophane insulin

\Biological substance\Protein and/or protein derivative\Protein\Protamine and/or protamine derivative (substance)\Isophane insulin
\Biological substance\Polypeptide\Protein\Protamine and/or protamine derivative (substance)\Isophane insulin
\Biological substance\Polypeptide\Polypeptide hormone\Insulin\Isophane insulin

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Isophane insulin	Is a	Intermediate-acting insulin	false	Inferred relationship	Some
Isophane insulin	Is a	protamine et/ou composé de protamine	false	Inferred relationship	Some
Isophane insulin	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Pancreatic hormone (disposition)	true	Inferred relationship	Some
Isophane insulin	Is a	Protamine and/or protamine derivative (substance)	true	Inferred relationship	Some
Isophane insulin	Is a	Insulin	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Isophane insulin adverse reaction	Causative agent (attribute)	True	Isophane insulin	Inferred relationship	Some	1
Porcine isophane insulin (substance)	Is a	True	Isophane insulin	Inferred relationship	Some
Isophane insulin nph	Is a	False	Isophane insulin	Inferred relationship	Some
Allergy to isophane insulin	Causative agent (attribute)	False	Isophane insulin	Inferred relationship	Some
Bovine isophane insulin (substance)	Is a	True	Isophane insulin	Inferred relationship	Some
Human isophane insulin (substance)	Is a	True	Isophane insulin	Inferred relationship	Some
insuline isophane humaine, 100 unités/mL, cartouche de 3 mL de suspension injectable	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane human 100units/mL injection suspension 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing isophane insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Isophane insulin nph	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane porcine 100u/mL injection solution 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 10/90 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 10/90 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 10/90 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 20/80 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 20/80 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 20/80 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 30/70 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 30/70 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 30/70 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 30/70 100u/mL injection solution 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 40/60 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 40/60 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 40/60 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 50/50 100u/mL injection solution 5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 50/50 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 50/50 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 50/50 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 50/50 100u/mL injection solution 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 15/85 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 15/85 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 15/85 100u/mL injection solution 5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 25/75 100u/mL injection solution 3mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 25/75 100u/mL injection solution 3mL prefilled pen	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane human 25/75 100u/mL injection solution 5mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane porcine 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane porcine 30/70 100u/mL injection solution 10mL vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin biphasic isophane porcine 30/70 100u/mL injection solution 1.5mL cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing porcine isophane insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing human isophane insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing bovine isophane insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing biphasic isophane insulin porcine	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Product containing biphasic isophane insulin human	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane human 100units/ml injection 1.5ml cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane human 100units/ml injection 10ml vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane biphasic human 20/80 100units/ml injection 3ml pre-filled disposable injection device	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane biphasic human 10/90 100units/ml injection 3ml cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane human 100units/ml injection 5ml vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane bovine 100units/ml injection 10ml vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane bovine 100units/ml injection 1.5ml cartridge	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Insulin isophane biphasic human 15/85 100units/ml injection 5ml vial	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Isophane insulin	Inferred relationship	Some
Allergy to isophane insulin	Causative agent (attribute)	True	Isophane insulin	Inferred relationship	Some	1
Human isophane insulin (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Isophane insulin	Inferred relationship	Some
Bovine isophane insulin (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Isophane insulin	Inferred relationship	Some
Porcine isophane insulin (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Isophane insulin	Inferred relationship	Some
Product containing isophane insulin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Isophane insulin only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Isophane insulin only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Product containing isophane insulin and porcine regular insulin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Product containing only isophane insulin and porcine regular insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Product containing only isophane insulin and porcine regular insulin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Product containing only isophane insulin and recombinant human regular insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	2
Product containing only isophane insulin and recombinant human regular insulin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	2
Product containing isophane insulin and porcine regular insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	1
Product containing isophane insulin and recombinant human regular insulin (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	2
Product containing isophane insulin and recombinant human regular insulin in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Isophane insulin	Inferred relationship	Some	2

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Id	Description	Lang	Type	Status	Case?	Module
110251013	Isophane insulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
110253011	Neutral protamine hagedorn insulin	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
805991019	Isophane insulin (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3779434014	NPH (neutral protamine hagedorn) insulin	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
381000188110	insuline isophane	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module