Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Lipodystrophy of face (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Lipoatrophy caused by injected corticosteroid |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Localized idiopathic lipoatrophy |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Erythema nodosum due to coccidioidomycosis (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Acute erythema nodosum (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Lipoatrophy and lipodystrophy |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Localised lipoatrophy |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Lipodystrophia centrifugalis abdominalis infantalis |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Widespread lipoatrophy (disorder) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Erythema nodosum due to tuberculosis (disorder) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Subcutaneous fat necrosis of newborn |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Erythema nodosum due to bacterial infection (disorder) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Nodular fat necrosis |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Subcutaneous nodular fat necrosis in pancreatitis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Nodular fat necrosis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Excess panniculus of abdomen |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Congenital total lipodystrophy (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Acute panniculitis (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Lipodystrophy due to Human immunodeficiency virus infection and antiretroviral therapy |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Lipoatrophy due to Human immunodeficiency virus infection and treatment |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Infective panniculitis |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Chronic migratory panniculitis |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Lipoatrophy caused by antiretroviral drug |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Lipodystrophy caused by antiretroviral drug (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
A rare, genetic lipodystrophy characterized by a loss of subcutaneous adipose tissue from the trunk, buttocks and limbs; fat accumulation in the neck, face, axillary and pelvic regions; muscular hypertrophy; and usually associated with metabolic complications such as insulin resistance, diabetes mellitus, dyslipidemia and liver steatosis. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
4 |
Loss of subcutaneous fat overlying rib (finding) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Loss of subcutaneous fat overlying biceps muscle (finding) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Loss of subcutaneous fat overlying triceps muscle (finding) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare form of genetic lipodystrophy, reported in 3 patients from one family to date, characterized by generalized congenital lipodystrophy, low birth weight, progressive sensorineural deafness occurring in childhood, intellectual deficit, progressive osteopenia, delayed skeletal maturation, skeletal abnormalities described as slender, undermineralized tubular bones, and dense metaphyseal striations in the distal femur, ulna and radius of older patients. Autosomal recessive inheritance has been suggested. |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
6 |
Familial partial lipodystrophy, Kobberling type, is a very rare form of familial partial lipodystrophy of unknown etiology characterized by lipoatrophy that is confined to the limbs and a normal or increased fat distribution of the face, neck, and trunk. Arterial hypertension and diabetes have also been associated. Inheritance is thought to be autosomal dominant. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
4 |
A rare genetic lipodystrophy characterized by loss of subcutaneous fat layers on the limbs, lipodystrophy in the face and trunk and scleroderma-like skin disorders (thickened skin on the palms and soles and skin pigment changes on the limbs and trunk). Additional clinical signs include joint contractures, reduced relative body weight, a bird-like facial appearance with a beaked nose, micrognathia and insulin-resistant diabetes mellitus. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Genetic lipodystrophy (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Calcific panniculitis (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Calcific panniculitis (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Entire subcutaneous fatty tissue (body structure) |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Lipodermatosclerosis of lower limb due to varicose veins of lower limb |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
11 |
Lipodermatosclerosis of lower limb due to varicose veins of lower limb |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
9 |
Dermal-fat skin graft |
Procedure site - Direct (attribute) |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Grafting of skin and dermal-fat for breast augmentation |
Procedure site - Direct (attribute) |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
4 |
Dermal-fat-fascia graft |
Procedure site - Direct (attribute) |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare form of genetic lipodystrophy, reported in 3 patients from one family to date, characterized by generalized congenital lipodystrophy, low birth weight, progressive sensorineural deafness occurring in childhood, intellectual deficit, progressive osteopenia, delayed skeletal maturation, skeletal abnormalities described as slender, undermineralized tubular bones, and dense metaphyseal striations in the distal femur, ulna and radius of older patients. Autosomal recessive inheritance has been suggested. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Mandibuloacral dysostosis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
A rare granulomatous autoinflammatory syndrome characterized by infantile-onset, widespread, chronic, recurrent, progressive, lobular panniculitis associated with panuveitis, arthritis and severe systemic granulomatous inflammation. |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
A rare, genetic, neurodegenerative disorder characterized by progressive psychomotor and cognitive regression (manifesting with gait ataxia, spasticity, loss of language, mild to severe intellectual disability, pyramidal and extrapyramidal signs and, frequently, development of tetraplegia or tetraparesis) associated with variable degrees of lipodystrophy, hepatomegaly, hypertriglyceridemia and muscular hypertrophy. Hyperactivity, tremor and development of seizures may also be associated. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare systemic disease characterized by a neonatal progeroid appearance (not associated with other manifestations of premature aging) associated with facial dysmorphism (e.g. macrocephaly or arrested hydrocephaly, proptosis, downslanting palpebral fissures, retrognathia), generalized, extreme, congenital lack of subcutaneous fat tissue (except in the breast and iliac region) and incomplete signs of Marfan syndrome (mainly severe myopia, joint hyperextensibility and arachnodactyly). Metabolic disturbances are not associated. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Panniculitis-induced localized lipodystrophy is a rare, acquired, localized lipodystrophy disorder characterized by eruption of tender, occasionally painful, erythematous nodules and plaques which enlarge radially and resolve into lipoatrophic lesions, often located in the upper and lower limbs. Histologically, lesions are characterized by lipophagic, lobular panniculitis and absence of vasculitis. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Panniculitis-induced localized lipodystrophy is a rare, acquired, localized lipodystrophy disorder characterized by eruption of tender, occasionally painful, erythematous nodules and plaques which enlarge radially and resolve into lipoatrophic lesions, often located in the upper and lower limbs. Histologically, lesions are characterized by lipophagic, lobular panniculitis and absence of vasculitis. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
A rare genetic lipodystrophy characterized by loss of subcutaneous adipose tissue primarily affecting the lower limbs and gluteal region due to a defect in the PLIN1 gene. Associated features of insulin resistance, hepatic steatosis, dyslipidemia, hypertension, axillary acanthosis nigricans and muscular hypertrophy of the lower limbs are typical. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Dermal-fat skin graft |
Procedure site - Direct (attribute) |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Grafting of skin and dermal-fat for breast augmentation |
Procedure site - Direct (attribute) |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Michelin-tyre baby |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Erythema nodosum caused by drug |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Adiposis tuberosa simplex (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Erythema nodosum due to streptococcal infection (disorder) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Erythema nodosum due to Yersinia enterocolitica (disorder) |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Chronic migratory panniculitis |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
4 |
Erythema nodosum migrans |
Finding site |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
5 |
Lipodermatosclerosis of lower limb due to varicose veins of lower limb |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare granulomatous autoinflammatory syndrome characterized by infantile-onset, widespread, chronic, recurrent, progressive, lobular panniculitis associated with panuveitis, arthritis and severe systemic granulomatous inflammation. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Localised lipodystrophy |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Structure of subcutaneous fatty tissue of neck |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Lipoatrophy and lipodystrophy |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Lipoedematous alopecia |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Erythema nodosum due to systemic fungal infection (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Fat hypertrophy due to injection of drug or medicament (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Insulin lipohypertrophy |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Mandibuloacral dysostosis co-occurrent with type A lipodystrophy (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Mandibuloacral dysostosis co-occurrent with type B lipodystrophy (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Lipodystrophy due to juvenile dermatomyositis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Structure of subcutaneous fatty tissue overlying rib (body structure) |
Is a |
False |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Structure of subcutaneous fatty tissue overlying triceps muscle (body structure) |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Structure of subcutaneous fatty tissue overlying biceps muscle (body structure) |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Generalized congenital lipodystrophy with myopathy (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare familial partial lipodystrophy characterized by adult onset of distal lipoatrophy with gluteofemoral fat loss, as well as increased fat accumulation in the face and trunk and visceral adiposity. Additional manifestations include diabetes mellitus, atherogenic dyslipidemia, eyelid xanthelasmas, arterial hypertension, cardiovascular disease, hepatic steatosis, acanthosis nigricans on axillae and neck, hirsutism, and muscular hypertrophy of the lower limbs. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare familial partial lipodystrophy characterized by adult onset of distal lipoatrophy and severe insulin resistance in the liver and peripheral tissues, hyperinsulinemia, and diabetes mellitus. Acanthosis nigricans and hypertension have been reported in association. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare familial partial lipodystrophy characterized by severe partial lipoatrophy affecting the limbs, trunk, and abdomen, together with faciocervical fat accumulation. Additional manifestations include diabetes, acanthosis nigricans, liver steatosis, and hypertriglyceridemia, as well as low serum leptin and adiponectin levels. Severe cardiac rhythm and conduction disturbances have also been reported. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare, genetic lipodystrophy characterized by abnormal subcutaneous fat distribution, resulting in preservation of visceral, neck and axillary fat and absence of lower limb and femoro gluteal subcutaneous fat. Additional clinical features are acanthosis nigricans, insulin-resistant type II diabetes mellitus, dyslipidemia, and hypertension, leading to pancreatitis, hepatomegaly and hepatic steatosis. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare, genetic lipodystrophy characterized by abnormal subcutaneous fat distribution, resulting in excess accumulation of fat in the face, neck, shoulders, axillae, trunk and pubic region, and loss of subcutaneous fat from the lower extremities. Variable common additional features are progressive adult onset myopathy, insulin resistance, diabetes, hypertriglyceridemia, hepatic steatosis, and vitiligo. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Lipo-lymphoedema |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
A rare, genetic, primary lipodystrophy syndrome characterized by severe developmental delay and intellectual disability, hypertonia, hyperreflexia, microcephaly, tightly adherent skin, an aged appearance, severe generalized lipodystrophy, and distinct facial dysmorphism which includes large prominent eyes, narrow nasal bridge, tented upper lip vermilion, an open mouth, and high-arched palate. Laboratory analysis of serum and urine are normal. |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Lipedema of scalp (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Lipedema of lower extremity (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Liposuction of subcutaneous tissue |
Procedure site - Direct (attribute) |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
1 |
Structure of subcutaneous fatty tissue of head (body structure) |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Structure of subcutaneous fatty tissue of upper limb (body structure) |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Structure of subcutaneous fatty tissue of lower limb |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Structure of subcutaneous fatty tissue of trunk |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|
Liposuction of subcutaneous tissue |
Procedure site - Direct (attribute) |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Erythema nodosum due to yersiniosis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Sarcoidosis-induced erythema nodosum |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Erythema nodosum due to tuberculosis (disorder) |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
3 |
Chronic migratory panniculitis |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
2 |
Necrobiosis lipoidica diabeticorum |
Finding site |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
6 |
Structure of subcutaneous fatty tissue of buttock |
Is a |
True |
Subcutaneous fatty tissue |
Inferred relationship |
Some |
|