Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Entire hypothalamus |
Is a |
True |
Hypothalamic structure |
Inferred relationship |
Some |
|
Hypothalamic nucleus |
Is a |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Hypothalamus part |
Is a |
True |
Hypothalamic structure |
Inferred relationship |
Some |
|
Structure of diencephalic periventricular fibers |
Is a |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Hypothalamic tract |
Is a |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Structure of region of hypothalamus (body structure) |
Is a |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Pituitary structure |
Is a |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Craniopharyngioma |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic neuronal hamartoma |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Neoplasm of pituitary and suprasellar region |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Reduction anomaly of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
3 |
Neoplasm of hypothalamus (disorder) |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Benign tumor of pituitary and hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Suprasellar germ cell tumor |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
Malignant neoplasm of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Anomalies of hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Benign neoplasm of hypothalamus (disorder) |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic injury |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic amenorrhea |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Granuloma of pituitary and hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic granuloma (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Mass lesion of pituitary and hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic mass |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hamartoma of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic disorder of appetite |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Defective osmoregulation |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Osmoregulation defect - absent thirst |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Osmoregulation defect - excess thirst |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Absent osmoregulation |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Reset hypothalamic osmostat |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic overactivity |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Loss of hypothalamic inhibition |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic syndrome |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic obesity |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hamartoma of pituitary and hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
[X]Hypothalamic dysfunction, not elsewhere classified |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
|
Disorder of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Malignant neoplasm of pituitary and hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Gonadotropin releasing factor deficiency (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic neuronal hamartoma |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hamartoma of hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic mass |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic injury |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Anomalies of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hamartoma of pituitary and hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Malignant neoplasm of hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Benign neoplasm of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Mass lesion of pituitary and hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Neoplasm of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Malignant neoplasm of pituitary and hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Malignant epithelial neoplasm of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Anomalies of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
Secondary hypothalamic insufficiency (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Exercise induced hypothalamic insufficiency (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Malignant glioma of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Late-onset central hypoventilation co-occurrent and due to hypothalamic dysfunction (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypothalamic hamartomas with gelastic seizures is a rare cerebral malformation with epilepsy syndrome characterized by early-onset gelastic (i.e. ictal laughter) or dacrystic (i.e., ictal crying) seizures due to non-neoplastic developmental malformation - hypothalamic hamartomas. In many patients, seizures progress to other seizure types including focal and generalized seizures, with concomitant cognitive decline and behavioral disorders. Some patients also present a precocious puberty. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
A rare syndromic endocrine disease characterized by childhood-onset hyperphagia and obesity, alveolar hypoventilation, dysautonomia, hypothalamic dysfunction and neurobehavioral disorders. Central hypothyroidism, endocrine anomalies, electrolyte imbalances and respiratory failure may also be associated. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
Reduction anomaly of hypothalamus |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Neoplasm of uncertain behavior of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Hypoplasia of hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Primary malignant glioma of hypothalamus |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
Diencephalic syndrome of infancy |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
syndrome diencéphalique secondaire à un néoplasme |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
3 |
Diencephalic syndrome |
Finding site |
False |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
Adiposogenital dystrophy |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
4 |
Atrophy of hypothalamus (disorder) |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
A form of monogenic obesity with characteristics of severe early-onset obesity and marked hyperphagia. Patients with congenital leptin deficiency are severely hyperphagic from early infancy and, although birthweight is normal, they rapidly become obese during early childhood. An increased susceptibility to infections has also been reported in these infants and appears to be associated with reduced numbers of circulating CD4+ T cells, and impaired T cell proliferation and cytokine release. Absence of serum leptin is caused by homozygous frameshift or missense mutations in the ob gene (7q31.3) and is inherited as an autosomal recessive trait. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
4 |
A rare, genetic form of obesity characterized by morbid obesity, hypertension, type 2 diabetes mellitus and dyslipidemia leading to early coronary disease, myocardial infarction and congestive heart failure. Intellectual disability and decreased sperm count or azoospermia have also been reported. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
A rare, genetic form of obesity characterized by severe early-onset obesity, hyperphagia, insulin resistance with hyperinsulinemia, reduced adult final height, delayed speech and language development and a tendency for social isolation and aggressive behavior. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
1 |
A rare, genetic form of obesity characterized by severe early-onset obesity, hyperphagia, and variable presence of cognitive impairment and behavioral disorder, including autistic spectrum behavior, impaired concentration and memory deficit. Some patients present with Prader-Willi-like features such as hypotonia, developmental delay, intellectual disability, short stature, hypopituitarism and dysmorphic facial features. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
2 |
A rare genetic disease characterized by early-onset severe obesity due to mutations in single genes acting on the development and function of the hypothalamus or the leptin-melanocortin pathway, leading to disruption of energy homeostasis and endocrine dysfunction. Patients present with a body mass index over three standard deviations above normal at less than five years of age, accompanied by a variety of signs and symptoms according to the mutated gene, including hyperphagia, insulin resistance, reduced basal metabolic rate, or hypogonadism, among others. |
Finding site |
True |
Hypothalamic structure |
Inferred relationship |
Some |
2 |