Inbound Relationships |
Type |
Active |
Source |
Characteristic |
Refinability |
Group |
Nephrotic syndrome co-occurrent and due to systemic lupus erythematosus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
4 |
A rare, hereditary nephrotic syndrome characterized by proteinuria, hypoalbuminemia, edema, and hyperlipidemia, with an absence of response to an initial trial of corticosteroids (i.e. steroid-resistant nephrotic syndrome; SRNS) and a generally complicated course. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Non-amyloid fibrillary glomerulopathy (non-amyloid FGP) is a rare cause of glomerulonephritis (GN) characterized by glomerular accumulation of non-amyloid fibrils in the mesangium and the glomerular (and rarely tubular) basement membrane, that mainly presents with renal insufficiency, micro-hematuria and nephrotic range proteinuria. Non-amyloid FGP and immunotactoid glomerulopathy are often grouped together as pathogenetically related diseases. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Glomerulonephritis co-occurrent and due to scleroderma (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
5 |
Multi-drug resistant nephrotic syndrome (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Alport syndrome autosomal dominant (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Alport syndrome autosomal recessive (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Alport syndrome X-linked (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare constitutional hemolytic anemia that is characterized by the association of Alport syndrome, midface hypoplasia, intellectual deficit and elliptocytosis. It has been described in two families. The syndrome is transmitted as an X-linked trait is caused by a contiguous gene deletion in Xq22.3 involving several genes including COL4A5, FACL4 and AMMECR1. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
6 |
Glomerulonephritis co-occurrent and due to scleroderma (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Congenital nephrotic syndrome with evidence of diffuse mesangial sclerosis on histology or with DNA evidence of a genetic mutation associated with diffuse mesangial sclerosis. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare hereditary motor and sensory neuropathy disorder characterized by the typical CMT phenotype (slowly progressive distal muscle weakness and atrophy in upper and lower limbs, distal sensory loss in extremities, reduced or absent deep tendon reflexes and foot deformities) associated with focal segmental glomerulosclerosis (manifesting with proteinuria and progression to end-stage renal disease). Mild or moderate sensorineural hearing loss may also be associated. Nerve biopsy reveals both axonal and demyelinating changes and nerve conduction velocities vary from the demyelinating to axonal range (typically between 25-50m/sec). |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Idiopathic glomerular disease (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Glomerulonephritis with electron dense deposits in the glomerular baseement membrane in a patient with cancer, after exclusion of other possible causes of membranous glomerulonephritis. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Congenital nephrotic syndrome with evidence of an underlying congenital infection (e.g. syphilis, toxoplasmosis, rubella, hepatitis B). |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare glomerular disease, histologically characterized by thickening of the capillary wall, with immune deposits predominantly containing IgG4 and C3 on the sub-epithelial side, and typically manifesting with nephrotic syndrome. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Glomerulonephritis with electron dense deposits in the glomerular baseement membrane, associated with treatment with a drug known to be associated with membranous nephropathy and after exclusion of alternative causes. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Focal and segmental glomerulosclerosis in association with long-term treatment with lithium carbonate, after exclusion of alternative causes. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Focal and segmental glomerulosclerosis in a patient with sickle cell disease. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Glomerulonephritis with electron dense deposits in the glomerular baseement membrane, associated with an infection known to cause membranous nephropath and after exclusion of alternative causes. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
A rare, genetic multisystem disorder characterized by a neurodegenerative disorder associating global developmental delay, progressive microcephaly, and progressive cerebral and cerebellar atrophy with extrapyramidal involvement, progressive optic atrophy, and in many patients early-onset steroid-resistant nephrotic syndrome. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
syndrome de dyschondrostéose - néphropathie |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
A rare, genetic multisystem disorder characterized by a neurodegenerative disorder associating global developmental delay, progressive microcephaly, and progressive cerebral and cerebellar atrophy with extrapyramidal involvement, progressive optic atrophy, and in many patients early-onset steroid-resistant nephrotic syndrome. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Glomerular disorder due to non-neuropathic heredofamilial amyloidosis (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Recurrent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Recurrent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Persistent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Persistent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Complement component 3 glomerulopathy (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Complement component 3 glomerulopathy (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
A histological subtype of C3 glomerulopathy characterized by C3 deposition in renal tissue in the absence or near-absence of immunoglobulin deposits, in a patient with the classic clinical features of glomerulonephritis and electron microscopic findings of highly electron-dense intra-membranous, osmiophilic deposits. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
A histological subtype of C3 glomerulopathy characterized by C3 deposition in renal tissue in the absence or near-absence of immunoglobulin deposits, in a patient with the classic clinical features of glomerulonephritis and electron microscopic findings of highly electron-dense intra-membranous, osmiophilic deposits. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Complement component 3 glomerulonephritis (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Complement component 3 glomerulonephritis (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
An extremely rare syndromic lymphedema disorder characterized by early-onset hypotrichosis, childhood-onset lymphedema, and variable telangiectasia, particularly of the palms. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
6 |
A rare primary glomerular disease characterized by the association of congenital nephrotic syndrome, early onset renal failure and ocular anomalies with microcoria and severe neurodevelopment deficits. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare primary glomerular disease characterized by the association of congenital nephrotic syndrome, early onset renal failure and ocular anomalies with microcoria and severe neurodevelopment deficits. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
A rare a multisystem disorder characterized by spondyloepiphyseal dysplasia and disproportionate short stature, facial dysmorphism, T-cell immunodeficiency, and progressive, proteinuric steroid-resistant nephropathy. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
5 |
A rare, congenital glomerular disease due to maternal anti-neutral endopeptidase (NEP) alloimmunization characterized by severe renal failure and nephrotic syndrome at birth, which rapidly improves in the first weeks of life. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Immunotactoid glomerulopathy (ITG) is a very rare condition characterized by glomerular accumulation of microtubules in the mesangium and the glomerular basement membrane, that mainly presents with proteinuria, micro-hematuria, nephrotic syndrome, renal insufficiency and hematologic malignancy. ITG and non-amyloid fibrillary glomerulopathy are often grouped together as pathogenetically related diseases. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare renal disease characterized by the association of X-linked Alport syndrome (glomerular nephropathy, sensorineural deafness and ocular anomalies) and benign proliferation of visceral smooth muscle cells along the gastrointestinal, respiratory, and female genital tracts and clinically manifests with dysphagia, dyspnea, cough, stridor, postprandial vomiting, retrosternal or epigastric pain, recurrent pneumonia, and clitoral hypertrophy in females. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Persistent proteinuria (finding) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare intellectual disability syndrome characterized by intellectual deficit, marfanoid habitus, microcephaly, and glomerulonephritis. There have been no further reports since 1992. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Congenital nephrotic syndrome, interstitial lung disease, epidermolysis bullosa syndrome |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Granulomatosis with polyangiitis |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Granulomatosis with polyangiitis of gingiva |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Limited granulomatosis with polyangiitis |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Granulomatosis with polyangiitis with multisystem involvement |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Granulomatosis with polyangiitis of nose |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Granulomatosis with polyangiitis of larynx |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Glomerulonephritis due to granulomatosis with polyangiitis |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
5 |
Glomerulonephritis co-occurrent and due to antineutrophil cytoplasmic antibody positive vasculitis (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
5 |
Persistent albuminuria (finding) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Cr51 EDTA clearance study |
Procedure site - Direct (attribute) |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Vasculitis with glomerulonephritis |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare renal disease characterized by glomerular nephropathy with hematuria progressing to end-stage renal disease (ESRD), frequently associated with sensorineural deafness, and occasionally with ocular anomalies. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Nephrotic syndrome in malaria |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
LAMB2-related infantile-onset nephrotic syndrome |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare intellectual disability syndrome characterized by intellectual deficit, marfanoid habitus, microcephaly, and glomerulonephritis. There have been no further reports since 1992. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare a multisystem disorder characterized by spondyloepiphyseal dysplasia and disproportionate short stature, facial dysmorphism, T-cell immunodeficiency, and progressive, proteinuric steroid-resistant nephropathy. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
syndrome de dyschondrostéose - néphropathie |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare constitutional hemolytic anemia that is characterized by the association of Alport syndrome, midface hypoplasia, intellectual deficit and elliptocytosis. It has been described in two families. The syndrome is transmitted as an X-linked trait is caused by a contiguous gene deletion in Xq22.3 involving several genes including COL4A5, FACL4 and AMMECR1. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare hereditary motor and sensory neuropathy disorder characterized by the typical CMT phenotype (slowly progressive distal muscle weakness and atrophy in upper and lower limbs, distal sensory loss in extremities, reduced or absent deep tendon reflexes and foot deformities) associated with focal segmental glomerulosclerosis (manifesting with proteinuria and progression to end-stage renal disease). Mild or moderate sensorineural hearing loss may also be associated. Nerve biopsy reveals both axonal and demyelinating changes and nerve conduction velocities vary from the demyelinating to axonal range (typically between 25-50m/sec). |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
A rare, genetic, renal disease characterized by hereditary nephritis leading to nephrotic syndrome and end-stage renal failure associated with sensorineural hearing loss and pretibial skin blistering followed by atrophy. Other reported manifestations include bilateral lacrimal duct stenosis, dystrophic teeth and nails, bilateral cervical ribs, unilateral kidney, distal vaginal agenesis and anemia due to beta-thalassemia minor. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Chronic nephritic syndrome |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Nephrotic-nephritic syndrome |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Chronic nephritic syndrome, minor glomerular abnormality |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Nephritic syndrome |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Glomerulonephritis with electron dense deposits in the glomerular baseement membrane, associated with treatment with a drug known to be associated with membranous nephropathy and after exclusion of alternative causes. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Membranous glomerulonephritis - stage III |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Complement component 3 glomerulonephritis (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A histological subtype of C3 glomerulopathy characterized by C3 deposition in renal tissue in the absence or near-absence of immunoglobulin deposits, in a patient with the classic clinical features of glomerulonephritis and electron microscopic findings of highly electron-dense intra-membranous, osmiophilic deposits. |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Complement component 3 glomerulopathy (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Acute glomerulonephritis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Microalbuminuric diabetic nephropathy |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Microalbuminuria due to type 1 diabetes mellitus |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Persistent microalbuminuria due to type 2 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Microalbuminuria due to type 2 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Proteinuric nephropathy due to diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Recurrent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Persistent hematuria co-occurrent and due to dense deposit disease (disorder) |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Persistent microalbuminuria due to type 1 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Proteinuria due to type 1 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Glomerulopathy due to diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
A rare, genetic coenzyme Q10 deficiency characterized by sensorineural deafness and severe, progressive nephrotic syndrome not responding to steroid treatment. Clinical manifestations include early onset proteinuria, hypoalbuminemia and edema, leading to end-stage renal disease. The renal biopsy reveals focal segmental glomerulosclerosis and diffuse mesangial sclerosis. Rarely, seizures, ataxia and dysmorphic features have been described. |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Persistent proteinuria due to type 1 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Acute nephrotic syndrome (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Acute glomerulonephritis associated with another disorder (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Proteinuria due to type 2 diabetes mellitus |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Persistent proteinuria due to type 2 diabetes mellitus (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
3 |
Leigh-Syndrom mit nephrotischem Syndrom |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
5 |
Subacute glomerulonephritis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Immune-complex glomerulonephritis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Glomerulonephritis co-occurrent and due to antineutrophil cytoplasmic antibody positive vasculitis (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
2 |
Glomerulitis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Chronic nephritic syndrome |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
4 |
Goodpasture's disease |
Finding site |
False |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Mesangial proliferative glomerulonephritis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Glomerulonephritis |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |
Nephrotic-nephritic syndrome |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
5 |
Non-progressive hereditary glomerulonephritis (disorder) |
Finding site |
True |
Glomerulus structure |
Inferred relationship |
Some |
1 |