68540007: Nicotine (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with etiopathic disposition mechanism of action (substance)\Toxic, noxious, or poisonous substance that is produced by a living organism.\Phytotoxin\Nicotine
\Substance categorized by disposition\Receptor agonist\Acetylcholine receptor agonist\Nicotinic receptor agonist\Nicotine

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Autonomic agent (substance)\Parasympathomimetic agent (substance)\Acetylcholine receptor agonist\Nicotinic receptor agonist\Nicotine
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Central nervous system agent (substance)\Psychoactive substance (substance)\Nicotine

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Alkaloid (substance)\Naturally occurring alkaloid (substance)\Plant alkaloid\Nicotine

\Substance categorized functionally\Phytochemical\Plant alkaloid\Nicotine

\Material (substance)\Natural material\Organic natural material\Plant material\...

\Phytochemical\Plant alkaloid\Nicotine

\Plant product\Phytotoxin\Nicotine
\Plant product\Plant alkaloid\Nicotine

\Biological substance\Organic natural material\Plant material\...

\Phytochemical\Plant alkaloid\Nicotine

\Plant product\Phytotoxin\Nicotine
\Plant product\Plant alkaloid\Nicotine

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2002. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Nicotine	Is a	Plant alkaloid	true	Inferred relationship	Some
Nicotine	Is a	Phytotoxin	true	Inferred relationship	Some
Nicotine	Is a	classe d'allergènes	false	Inferred relationship	Some
Nicotine	Is a	Autonomic agent (substance)	false	Inferred relationship	Some
Nicotine	Is a	allergène médicamenteux	false	Inferred relationship	Some
Nicotine	Is a	Acetylcholine receptor agonist	false	Inferred relationship	Some
Nicotine	Is a	Psychoactive substance (substance)	true	Inferred relationship	Some
Nicotine	Is a	Nicotinic receptor agonist	true	Inferred relationship	Some
Nicotine	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Nicotinic receptor agonist (disposition)	true	Inferred relationship	Some
Nicotine	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that is produced by a living organism and is toxic, noxious, or poisonous.	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely nicotine 937.5 microgram/1 hour prolonged-release transdermal patch (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine cyclodextrin complex) 2 milligram/1 each conventional release sublingual tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine 500 microgram/actuation nasal spray	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine 500 microgram/actuation nasal spray	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nicotine	Inferred relationship	Some	1
Nicotine resin complex (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Nicotine	Inferred relationship	Some
Allergy to nicotine	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Nicotine adverse reaction	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Nicotine polacrilex	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Nicotine	Inferred relationship	Some
Product containing nicotine in pulmonary dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine-containing product in cutaneous dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Product containing nicotine in oromucosal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine only product in cutaneous dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine only product in nasal dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Product containing only nicotine in oromucosal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine only product in pulmonary dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Product containing only nicotine in transdermal dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine (as nicotine polacrilex) 2 mg oral gum chewing gum	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine polacrilex) 2 milligram/1 each conventional release oromucosal lozenge (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine polacrilex) 4 milligram/1 chewing gum prolonged-release oral gum (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine polacrilex) 1 milligram/1 each conventional release oromucosal lozenge (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine (as nicotine polacrilex) 4 mg oromucosal lozenge	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 917 microgram/1 hour prolonged-release transdermal patch (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 917 microgram/1 hour prolonged-release transdermal patch (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nicotine	Inferred relationship	Some	1
Nicotine 458 microgram/hour prolonged-release transdermal patch	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine 458 microgram/hour prolonged-release transdermal patch	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nicotine	Inferred relationship	Some	1
Product containing nicotine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Nicotine bitartrate dihydrate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	False	Nicotine	Inferred relationship	Some
Nicotine dependence in remission	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Tobacco dependence with current use	Causative agent (attribute)	False	Nicotine	Inferred relationship	Some	1
Tobacco dependence caused by cigarettes in remission	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 1 milligram/1 actuation conventional release oromucosal spray (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 1 milligram/1 actuation conventional release oromucosal spray (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine replacement therapy	Direct substance	True	Nicotine	Inferred relationship	Some	1
Nondependent harmful pattern of use of tobacco (disorder)	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 1.563 milligram/1 hour prolonged-release transdermal patch (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine 1.563 milligram/1 hour prolonged-release transdermal patch (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Tobacco dependence caused by chewing tobacco in remission	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	2
Nicotine (as nicotine polacrilex) 1.5 mg oromucosal lozenge	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine bitartrate) 1 milligram/1 each conventional release oromucosal lozenge (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Product containing precisely nicotine (as nicotine bitartrate) 2 milligram/1 each conventional release oromucosal lozenge (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nicotine	Inferred relationship	Some	1
Nicotine bitartrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Nicotine	Inferred relationship	Some
Nicotine pouch	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nicotine	Inferred relationship	Some	1
Disorder characterised by the pattern and consequences of nicotine use leading to clinically significant impairment or distress both to physical or mental health of the user or others around the user.	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
An episode of nicotine use that has caused clinically significant harm to a person's physical or mental health. Harm may be caused by the intoxicating effects of caffeine, the direct or secondary toxic effects on body organs and systems, or a harmful route of administration.	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Use of nicotine (observable entity)	This attribute specifies an entity that the process which the property characterizes specifically acts on.	True	Nicotine	Inferred relationship	Some	1
Qualitative measurement of nicotine in urine (procedure)	Component	True	Nicotine	Inferred relationship	Some	1
Maternal harmful pattern of use of tobacco (disorder)	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
A pattern of tobacco use that has caused damage to a person's physical or mental health. The pattern of tobacco use is observed for a minimum of 12 months for occasional use or at least one month for continuous use (daily or nearly daily). Harm to health results from direct or secondary toxic effects on body organs and systems or a harmful route of administration.	Causative agent (attribute)	True	Nicotine	Inferred relationship	Some	1
Nicotine betadex	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Nicotine	Inferred relationship	Some

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Id	Description	Lang	Type	Status	Case?	Module
113837018	Nicotine	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
808386011	Nicotine (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
50271000195114	nicotina	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
176181000077114	nicotine	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
64421000195114	Nicotin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
234461000195115	Nikotin	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module