702804006: Regorafenib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Angiogenesis inhibitor\Regorafenib
\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Regorafenib
\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)\Regorafenib

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Regorafenib

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Pyridine\Regorafenib

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyridine and/or pyridine derivative\Pyridine\Regorafenib
\Organic compound\Urea and/or urea derivative\Phenylurea compound (substance)\Regorafenib
\Organic compound\Organic nitrogen compound\Pyridine and/or pyridine derivative\Pyridine\Regorafenib
\Organic compound\Hydrocarbon\Aromatic hydrocarbon\Substance with benzene structure\Phenylurea compound (substance)\Regorafenib

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Regorafenib	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Regorafenib	Is a	Angiogenesis inhibitor	true	Inferred relationship	Some
Regorafenib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Angiogenesis inhibitor (disposition)	true	Inferred relationship	Some
Regorafenib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Regorafenib	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Regorafenib	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Regorafenib	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Regorafenib	Is a	Benzene	false	Inferred relationship	Some
Regorafenib	Is a	Pyridine	true	Inferred relationship	Some
Regorafenib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Vascular endothelial growth factor receptor antagonist (disposition)	true	Inferred relationship	Some
Regorafenib	Is a	Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some
Regorafenib	Is a	Phenylurea compound (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing regorafenib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Regorafenib	Inferred relationship	Some	1
Regorafenib 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Regorafenib	Inferred relationship	Some
Regorafenib 40 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Regorafenib	Inferred relationship	Some	1
Regorafenib 40 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Regorafenib	Inferred relationship	Some	1
Regorafenib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Regorafenib	Inferred relationship	Some	1
Regorafenib 40 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Regorafenib	Inferred relationship	Some	1
Product containing only regorafenib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Regorafenib	Inferred relationship	Some	1
Regorafenib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Regorafenib	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3006131011	Regorafenib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3006151010	Regorafenib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
365061000195112	regorafenib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
26001000188115	regorafénib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
837731000172110	régorafénib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3339991001000112	Regorafenib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module