703128001: Bosutinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Bosutinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Bosutinib (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Quinoline\Aminoquinoline\Bosutinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Halogen and/or halogen compound\Chlorine and/or chlorine compound\Chlorine compound\Organic chloride compound\Chlorinated hydrocarbon\Dichlorobenzene\Bosutinib (substance)
\Halogen and/or halogen compound\Halogenated hydrocarbon\Chlorinated hydrocarbon\Dichlorobenzene\Bosutinib (substance)

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Amine and/or amine derivative\Quinoline\Aminoquinoline\Bosutinib (substance)

\Nitrile\Bosutinib (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinoline\Aminoquinoline\Bosutinib (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Aminoquinoline\Bosutinib (substance)
\Organic compound\Organic nitrogen compound\Nitrile\Bosutinib (substance)
\Organic compound\Organic chloride compound\Chlorinated hydrocarbon\Dichlorobenzene\Bosutinib (substance)
\Organic compound\Hydrocarbon\Halogenated hydrocarbon\Chlorinated hydrocarbon\Dichlorobenzene\Bosutinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Bosutinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Bosutinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Bosutinib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Bosutinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Bosutinib (substance)	Is a	Dichlorobenzene	true	Inferred relationship	Some
Bosutinib (substance)	Is a	Nitrile	true	Inferred relationship	Some
Bosutinib (substance)	Is a	Aminoquinoline	true	Inferred relationship	Some
Bosutinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Bosutinib monohydrate (substance)	Is a	False	Bosutinib (substance)	Inferred relationship	Some
Product containing bosutinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib monohydrate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Bosutinib (substance)	Inferred relationship	Some
Bosutinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Bosutinib (substance)	Inferred relationship	Some	1
Product containing only bosutinib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Bosutinib (substance)	Inferred relationship	Some	1
Product containing precisely bosutinib (as bosutinib monohydrate) 100 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Bosutinib (substance)	Inferred relationship	Some	1
Product containing precisely bosutinib (as bosutinib monohydrate) 500 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 100 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 100 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 500 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 400 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 400 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Bosutinib (substance)	Inferred relationship	Some	1
Bosutinib 500 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Bosutinib (substance)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

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Id	Description	Lang	Type	Status	Case?	Module
3007236019	Bosutinib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3007295017	Bosutinib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
50851000195117	bosutinib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
795511000172112	bosutinib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
64961000195110	Bosutinib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module