703350008: Apremilast (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Phosphodiesterase inhibitor\Phosphodiesterase 4 inhibitor\Apremilast (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Apremilast (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Analgesic (substance)\Non-opioid analgesic (substance)\Non-steroidal anti-inflammatory agent (substance)\Apremilast (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunosuppressant (substance)\Apremilast (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Sulfur and/or sulfur compound\Sulfur compound\Sulfone (substance)\Apremilast (substance)

\Organic compound\Substance with ether structure\Apremilast (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Apremilast (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Apremilast (substance)	Is a	Phosphodiesterase 4 inhibitor	true	Inferred relationship	Some
Apremilast (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Phosphodiesterase 4 inhibitor (disposition)	true	Inferred relationship	Some
Apremilast (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Apremilast (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Apremilast (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some
Apremilast (substance)	Is a	éther	false	Inferred relationship	Some
Apremilast (substance)	Is a	Sulfone (substance)	true	Inferred relationship	Some
Apremilast (substance)	Is a	Non-steroidal anti-inflammatory agent (substance)	true	Inferred relationship	Some
Apremilast (substance)	Is a	Substance with ether structure	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing apremilast (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Apremilast (substance)	Inferred relationship	Some	1
Apremilast therapy (procedure)	Direct substance	True	Apremilast (substance)	Inferred relationship	Some	2
Product containing only apremilast (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Apremilast (substance)	Inferred relationship	Some	1
Product containing apremilast in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Apremilast (substance)	Inferred relationship	Some	1
Apremilast only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Apremilast (substance)	Inferred relationship	Some	1
Product containing precisely apremilast 20 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Apremilast (substance)	Inferred relationship	Some	1
Product containing precisely apremilast 20 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Apremilast (substance)	Inferred relationship	Some	1
Apremilast 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Apremilast (substance)	Inferred relationship	Some	1
Apremilast 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Apremilast (substance)	Inferred relationship	Some	1
Product containing precisely apremilast 30 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Apremilast (substance)	Inferred relationship	Some	1
Product containing precisely apremilast 30 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Apremilast (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3008257013	Apremilast (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3008336015	Apremilast	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
939571000195112	apremilast	it	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
792011000172110	aprémilast	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
901921000195114	Apremilast	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module