703579002: Afatinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Afatinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Afatinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinazoline (substance)\Afatinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3008890016 Afatinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3009246012 Afatinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

57581000195114 afatinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

789351000172118 afatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

72101000195111 Afatinib de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Afatinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Afatinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Afatinib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Afatinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Afatinib (substance)	Is a	Quinazoline (substance)	true	Inferred relationship	Some
Afatinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing afatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib dimaleate	Is a	False	Afatinib (substance)	Inferred relationship	Some
Afatinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib dimaleate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Afatinib (substance)	Inferred relationship	Some
Product containing only afatinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 40 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 20 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Afatinib (substance)	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 30 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Afatinib (substance)	Inferred relationship	Some	1
Product containing precisely afatinib (as afatinib dimaleate) 50 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Afatinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets