703582007: Afatinib dimaleate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Afatinib dimaleate

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Afatinib dimaleate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinazoline (substance)\Afatinib dimaleate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3009346014 Afatinib dimaleate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3009639013 Afatinib dimaleate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

789371000172113 dimaléate d'afatinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Afatinib dimaleate	Is a	Afatinib (substance)	false	Inferred relationship	Some
Afatinib dimaleate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Afatinib dimaleate	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Afatinib dimaleate	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Afatinib dimaleate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Afatinib (substance)	true	Inferred relationship	Some
Afatinib dimaleate	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Afatinib dimaleate	Is a	Quinazoline (substance)	true	Inferred relationship	Some
Afatinib dimaleate	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely afatinib dimaleate 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some
Product containing precisely afatinib dimaleate 30 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some
Product containing precisely afatinib dimaleate 40 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some
Product containing precisely afatinib dimaleate 20 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 20 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 30 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 30 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 40 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 40 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 20 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 30 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib dimaleate 40 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Afatinib dimaleate	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 40 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Afatinib dimaleate	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 20 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Afatinib dimaleate	Inferred relationship	Some	1
Afatinib (as afatinib dimaleate) 30 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Afatinib dimaleate	Inferred relationship	Some	1
Product containing precisely afatinib (as afatinib dimaleate) 50 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Afatinib dimaleate	Inferred relationship	Some	1

This concept is not in any reference sets