703823007: Ivacaftor (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)\Ivacaftor (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Respiratory system agent (substance)\Ivacaftor (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Quinoline\Ivacaftor (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Ivacaftor (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinoline\Ivacaftor (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Ivacaftor (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ivacaftor (substance)	Is a	Phenolics	false	Inferred relationship	Some
Ivacaftor (substance)	Is a	Quinoline	true	Inferred relationship	Some
Ivacaftor (substance)	Is a	Respiratory system agent (substance)	true	Inferred relationship	Some
Ivacaftor (substance)	Is a	Substance with cystic fibrosis transmembrane conductance regulator potentiator mechanism of action (substance)	true	Inferred relationship	Some
Ivacaftor (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Cystic fibrosis transmembrane conductance regulator potentiator (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing ivacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 150 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ivacaftor (substance)	Inferred relationship	Some
Ivacaftor 150 mg oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 150 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing ivacaftor and lumacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing ivacaftor and lumacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 150 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor- and tezacaftor-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only ivacaftor and lumacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only ivacaftor and tezacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only ivacaftor (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only ivacaftor and lumacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor and tezacaftor only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only ivacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor- and ivacaftor- and tezacaftor-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing elexacaftor and ivacaftor and tezacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor and ivacaftor and tezacaftor only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing only elexacaftor and ivacaftor and tezacaftor in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 50 milligram/1 sachet conventional release oral granules (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 50 milligram/1 sachet conventional release oral granules (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 25 milligram/1 sachet conventional release oral granules (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 25 milligram/1 sachet conventional release oral granules (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 75 mg oral granules sachet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 75 mg oral granules sachet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 75 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Ivacaftor 75 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor 50 mg and ivacaftor 37.5 mg and tezacaftor 25 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor 100 mg and ivacaftor 75 mg and tezacaftor 50 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Elexacaftor 100 mg and ivacaftor 75 mg and tezacaftor 50 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 150 milligram and tezacaftor 100 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ivacaftor (substance)	Inferred relationship	Some	1
Product containing precisely ivacaftor 75 milligram and tezacaftor 50 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ivacaftor (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3009451016	Ivacaftor (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3009730015	Ivacaftor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
56251000195116	ivacaftor	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
819281000172117	ivacaftor	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
71241000195110	Ivacaftor	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module