703840003: Aflibercept (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Angiogenesis inhibitor\Aflibercept
\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)\Aflibercept

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Aflibercept

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Recombinant protein (substance)\Fusion protein (substance)\Aflibercept

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Recombinant protein (substance)\Fusion protein (substance)\Aflibercept

\Biological substance\Protein and/or protein derivative\Protein\Recombinant protein (substance)\Fusion protein (substance)\Aflibercept
\Biological substance\Polypeptide\Protein\Recombinant protein (substance)\Fusion protein (substance)\Aflibercept

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2014. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3009274019 Aflibercept en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3009606010 Aflibercept (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

55591000195117 aflibercept it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

789391000172114 aflibercept fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

70631000195112 Aflibercept de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Aflibercept	Is a	Fusion protein (substance)	true	Inferred relationship	Some
Aflibercept	Is a	Angiogenesis inhibitor	true	Inferred relationship	Some
Aflibercept	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Angiogenesis inhibitor (disposition)	true	Inferred relationship	Some
Aflibercept	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Aflibercept	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Vascular endothelial growth factor receptor antagonist (disposition)	true	Inferred relationship	Some
Aflibercept	Is a	Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing aflibercept (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aflibercept	Inferred relationship	Some	1
Aflibercept-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aflibercept	Inferred relationship	Some	1
Aflibercept only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aflibercept	Inferred relationship	Some	1
Product containing only aflibercept in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Aflibercept	Inferred relationship	Some	1
Product containing precisely aflibercept 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Aflibercept	Inferred relationship	Some	1
Product containing precisely aflibercept 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Aflibercept	Inferred relationship	Some	1

This concept is not in any reference sets