704191007: Nivolumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Immunomodulator\Substance with immune checkpoint inhibitor mechanism of action (substance)\Substance with programmed cell death protein 1 inhibitor mechanism of action (substance)\Nivolumab (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Nivolumab (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Monoclonal antibody\Nivolumab (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Nivolumab (substance)

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Nivolumab (substance)

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Nivolumab (substance)
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Nivolumab (substance)
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Nivolumab (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Nivolumab (substance)	Is a	agent d'anticorps monoclonal	false	Inferred relationship	Some
Nivolumab (substance)	Is a	Monoclonal antibody	true	Inferred relationship	Some
Nivolumab (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Programmed cell death protein 1 inhibitor (disposition)	true	Inferred relationship	Some
Nivolumab (substance)	Is a	Substance with programmed cell death protein 1 inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Nivolumab (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing nivolumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nivolumab (substance)	Inferred relationship	Some	1
Product containing nivolumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nivolumab (substance)	Inferred relationship	Some	1
Product containing only nivolumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nivolumab (substance)	Inferred relationship	Some	1
Nivolumab only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Nivolumab (substance)	Inferred relationship	Some	1
Nivolumab 10 mg/mL solution for infusion	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Nivolumab (substance)	Inferred relationship	Some	1
Nivolumab 10 mg/mL solution for infusion	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Nivolumab (substance)	Inferred relationship	Some	1

Reference Sets

Description inactivation indicator reference set

GB English

US English

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Id	Description	Lang	Type	Status	Case?	Module
3011226014	Nivolumab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3012383017	Nivolumab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
55111000195115	nivolumab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
828431000172117	nivolumab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
69661000195117	Nivolumab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module