704226002: Pertuzumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\...

\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Pertuzumab

\Enzyme inhibitor protein\Pertuzumab

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Epidermal growth factor receptor inhibitor\Human epidermal growth factor receptor 2 inhibitor\Pertuzumab
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Enzyme inhibitor protein\Pertuzumab
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Monoclonal antibody\Pertuzumab

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\...

\Enzyme inhibitor protein\Pertuzumab

\Antibody\Monoclonal antibody\Pertuzumab

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\...

\Enzyme inhibitor protein\Pertuzumab

\Antibody\Monoclonal antibody\Pertuzumab

\Biological substance\Protein and/or protein derivative\Protein\Enzyme inhibitor protein\Pertuzumab
\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Pertuzumab
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Pertuzumab
\Biological substance\Polypeptide\Protein\Enzyme inhibitor protein\Pertuzumab
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Pertuzumab

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Pertuzumab	Is a	agent d'anticorps monoclonal	false	Inferred relationship	Some
Pertuzumab	Is a	Monoclonal antibody	true	Inferred relationship	Some
Pertuzumab	Is a	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Pertuzumab	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Human epidermal growth factor receptor 2 inhibitor	true	Inferred relationship	Some
Pertuzumab	Is a	Antineoplastic agent (substance)	false	Inferred relationship	Some
Pertuzumab	Is a	Enzyme inhibitor protein	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Pertuzumab 30mg/mL solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Pertuzumab	Inferred relationship	Some
Product containing pertuzumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	1
Pertuzumab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	1
Pertuzumab-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	1
Product containing only pertuzumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	1
Product containing precisely pertuzumab 80 milligram/1 milliliter and trastuzumab 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Pertuzumab	Inferred relationship	Some	2
Product containing precisely pertuzumab 80 milligram/1 milliliter and trastuzumab 40 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Pertuzumab	Inferred relationship	Some	2
Product containing precisely pertuzumab 60 milligram/1 milliliter and trastuzumab 60 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Pertuzumab	Inferred relationship	Some	2
Product containing precisely pertuzumab 60 milligram/1 milliliter and trastuzumab 60 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Pertuzumab	Inferred relationship	Some	2
Pertuzumab and trastuzumab only product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	2
Product containing pertuzumab and trastuzumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	2
Pertuzumab and trastuzumab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	2
Product containing pertuzumab and trastuzumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Pertuzumab	Inferred relationship	Some	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3012148012	Pertuzumab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3012447013	Pertuzumab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
53621000195115	pertuzumab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
832451000172114	pertuzumab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
68541000195114	Pertuzumab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module