704259004: Ramucirumab (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with receptor antagonist mechanism of action (substance)\Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)\Ramucirumab

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Ramucirumab
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Monoclonal antibody\Ramucirumab

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Ramucirumab

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Ramucirumab

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Ramucirumab
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Ramucirumab
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Ramucirumab

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Ramucirumab	Is a	agent d'anticorps monoclonal	false	Inferred relationship	Some
Ramucirumab	Is a	Monoclonal antibody	true	Inferred relationship	Some
Ramucirumab	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Vascular endothelial growth factor receptor antagonist (disposition)	true	Inferred relationship	Some
Ramucirumab	Is a	Substance with vascular endothelial growth factor receptor antagonist mechanism of action (substance)	true	Inferred relationship	Some
Ramucirumab	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing ramucirumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ramucirumab	Inferred relationship	Some	1
Ramucirumab 10mg/mL solution for intravenous infusion	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ramucirumab	Inferred relationship	Some
Ramucirumab 10mg/mL conventional release solution for injection	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Ramucirumab	Inferred relationship	Some
Product containing only ramucirumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ramucirumab	Inferred relationship	Some	1
Ramucirumab-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ramucirumab	Inferred relationship	Some	1
Product containing only ramucirumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Ramucirumab	Inferred relationship	Some	1
Ramucirumab 10 mg/mL solution for injection	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Ramucirumab	Inferred relationship	Some	1
Ramucirumab 10 mg/mL solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Ramucirumab	Inferred relationship	Some	1

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3011387018	Ramucirumab	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3011432018	Ramucirumab (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
49451000195114	ramucirumab	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
837471000172116	ramucirumab	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
63601000195118	Ramucirumab	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module