704313003: Tofacitinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Janus kinase inhibitor\Tofacitinib (substance)
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Tofacitinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunosuppressant (substance)\Tofacitinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Nitrile\Tofacitinib (substance)

\Organic compound\Organic nitrogen compound\Nitrile\Tofacitinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3012802017 Tofacitinib (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3012869011 Tofacitinib en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

364451000195119 tofacitinib it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

846541000172111 tofacitinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

3336551001000119 Tofacitinib de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tofacitinib (substance)	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	agent antirhumatismal	false	Inferred relationship	Some
Tofacitinib (substance)	Is a	Janus kinase inhibitor	true	Inferred relationship	Some
Tofacitinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Janus kinase inhibitor (disposition)	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Tofacitinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some
Tofacitinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Tofacitinib (substance)	Is a	Nitrile	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Tofacitinib citrate	Is a	False	Tofacitinib (substance)	Inferred relationship	Some
Product containing tofacitinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib therapy (procedure)	Direct substance	True	Tofacitinib (substance)	Inferred relationship	Some	2
Tofacitinib citrate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Tofacitinib (substance)	Inferred relationship	Some
Tofacitinib-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing only tofacitinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 5 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 11 milligram/1 each prolonged-release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tofacitinib (substance)	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 1 mg/mL oral solution	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Tofacitinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets