704314009: Tofacitinib citrate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Janus kinase inhibitor\Tofacitinib citrate
\Substance categorized by disposition\Immunomodulator\Immunosuppressant (substance)\Tofacitinib citrate

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Immunosuppressant (substance)\Tofacitinib citrate

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Nitrile\Tofacitinib citrate

\Organic compound\Organic nitrogen compound\Nitrile\Tofacitinib citrate

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2015. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3012850018 Tofacitinib citrate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3012865017 Tofacitinib citrate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

846561000172110 citrate de tofacitinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Tofacitinib citrate	Is a	Tofacitinib (substance)	false	Inferred relationship	Some
Tofacitinib citrate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Janus kinase inhibitor (disposition)	true	Inferred relationship	Some
Tofacitinib citrate	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Tofacitinib (substance)	true	Inferred relationship	Some
Tofacitinib citrate	Is a	Janus kinase inhibitor	true	Inferred relationship	Some
Tofacitinib citrate	Is a	Immunosuppressant (substance)	true	Inferred relationship	Some
Tofacitinib citrate	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Tofacitinib citrate	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	A substance that modifies the immune response or the functioning of the immune system.	true	Inferred relationship	Some
Tofacitinib citrate	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Tofacitinib citrate	Is a	Nitrile	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely tofacitinib citrate 5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tofacitinib citrate	Inferred relationship	Some
Product containing precisely tofacitinib citrate 5 milligram/1 each conventional release oral tablet	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	False	Tofacitinib citrate	Inferred relationship	Some	1
Product containing precisely tofacitinib citrate 5 milligram/1 each conventional release oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	False	Tofacitinib citrate	Inferred relationship	Some	1
Product containing precisely tofacitinib citrate 5 milligram/1 each conventional release oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	False	Tofacitinib citrate	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 5 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tofacitinib citrate	Inferred relationship	Some	1
Product containing precisely tofacitinib (as tofacitinib citrate) 11 milligram/1 each prolonged-release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tofacitinib citrate	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 10 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tofacitinib citrate	Inferred relationship	Some	1
Tofacitinib (as tofacitinib citrate) 1 mg/mL oral solution	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Tofacitinib citrate	Inferred relationship	Some	1

This concept is not in any reference sets