713464000: Dolutegravir (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Anti-infective agent (substance)\Substance with antiviral mechanism of action (substance)\Substance with antiretroviral mechanism of action (substance)\Integrase strand transfer inhibitor\Dolutegravir

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Dolutegravir

\Organic compound\Organic cyclic compound\Heterocyclic compound\Pyrimidine and/or pyrimidine derivative\Dolutegravir
\Organic compound\Organic nitrogen compound\Pyrimidine and/or pyrimidine derivative\Dolutegravir

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2016. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Dolutegravir	Is a	Pyrimidine and/or pyrimidine derivative	true	Inferred relationship	Some
Dolutegravir	Is a	Integrase strand transfer inhibitor	true	Inferred relationship	Some
Dolutegravir	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Integrase strand transfer inhibitor (disposition)	true	Inferred relationship	Some
Dolutegravir	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Dolutegravir	Is a	Nucleotidyltransferase inhibitor	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Dolutegravir sodium	Is a	False	Dolutegravir	Inferred relationship	Some
Product containing dolutegravir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	1
Product containing dolutegravir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	1
Product containing abacavir and dolutegravir and lamivudine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Product containing abacavir and dolutegravir and lamivudine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Product containing dolutegravir and rilpivirine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Product containing dolutegravir and rilpivirine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Dolutegravir (as dolutegravir sodium) 10 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	1
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	1
Product containing precisely dolutegravir (as dolutegravir sodium) 25 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	1
Dolutegravir sodium	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Dolutegravir	Inferred relationship	Some
Abacavir and dolutegravir and lamivudine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Abacavir and dolutegravir and lamivudine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Product containing only dolutegravir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	1
Product containing only dolutegravir and rilpivirine (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Dolutegravir and rilpivirine only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Product containing only dolutegravir in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	1
Dolutegravir- and lamivudine-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Dolutegravir and lamivudine only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Product containing dolutegravir and lamivudine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Product containing only dolutegravir and lamivudine in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	2
Product containing only dolutegravir and lamivudine and tenofovir (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram and lamivudine 300 milligram and tenofovir disoproxil (as tenofovir disoproxil fumarate) 245 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	3
Dolutegravir and lamivudine and tenofovir only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Dolutegravir- and lamivudine- and tenofovir-containing product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Dolutegravir- and lamivudine- and tenofovir-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dolutegravir	Inferred relationship	Some	3
Product containing precisely abacavir (as abacavir sulfate) 600 milligram and dolutegravir (as dolutegravir sodium) 50 milligram and lamivudine 300 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	3
Product containing precisely dolutegravir (as dolutegravir sodium) 5 milligram/1 each conventional release orodispersible tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	1
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram and lamivudine 300 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	2
Product containing precisely dolutegravir (as dolutegravir sodium) 50 milligram and rilpivirine (as rilpivirine hydrochloride) 25 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dolutegravir	Inferred relationship	Some	2

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3289426016	Dolutegravir	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3289450019	Dolutegravir (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
52851000195116	dolutegravir	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
807021000172115	dolutégravir	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
67721000195113	Dolutegravir	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module