716072000: Sacubitril (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Hydrolase inhibitor\Peptide hydrolase inhibitor\Substance with neprilysin inhibitor mechanism of action (substance)\Sacubitril (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\Organic compound\Hydrocarbon\Aromatic hydrocarbon\Diphenyl\Sacubitril (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2016. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3304648016 Sacubitril (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3304649012 Sacubitril en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

55361000195116 sacubitril it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

839151000172110 sacubitril fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

70351000195110 Sacubitril de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Sacubitril (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Sacubitril (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Compound or agent that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction US Library of Medicine MESH Descriptor data Accessed 20/01/2017	false	Inferred relationship	Some
Sacubitril (substance)	Is a	produit chimique catégorisé selon sa fonction	false	Inferred relationship	Some
Sacubitril (substance)	Is a	Substance with neprilysin inhibitor mechanism of action (substance)	true	Inferred relationship	Some
Sacubitril (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Neprilysin inhibitor (disposition)	true	Inferred relationship	Some
Sacubitril (substance)	Is a	Diphenyl	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing sacubitril and valsartan (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril- and valsartan-containing product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril and valsartan only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril and valsartan only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Sacubitril (substance)	Inferred relationship	Some	2
Product containing precisely sacubitril 24 milligram and valsartan 26 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sacubitril (substance)	Inferred relationship	Some	2
Product containing precisely sacubitril 24 milligram and valsartan 26 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril 49 mg and valsartan 51 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril 49 mg and valsartan 51 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril 97 mg and valsartan 103 mg oral tablet	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Sacubitril (substance)	Inferred relationship	Some	2
Sacubitril 97 mg and valsartan 103 mg oral tablet	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Sacubitril (substance)	Inferred relationship	Some	2

This concept is not in any reference sets