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721306009: Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder)


Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Mar 2023. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module
3324921010 Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core
3324922015 Therapy related acute myeloid leukemia and myelodysplastic syndrome en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
3324923013 Therapy related acute myeloid leukaemia and myelodysplastic syndrome en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core
935181000172110 leucémie aigüe myéloïde et syndromes myélodysplasiques thérapie-dépendants fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module
961901000172110 leucémie aigüe myéloïde secondaire fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module
3412741001000113 Therapiebedingte akute myeloische Leukämie und myelodysplastische Syndrome de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module


0 descendants.

Expanded Value Set


Outbound Relationships Type Target Active Characteristic Refinability Group Values
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Is a Acute myeloid leukemia, disease false Inferred relationship Some
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Associated morphology Therapy-related acute myeloid leukemia and myelodysplastic syndrome false Inferred relationship Some 1
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Finding site Bone marrow structure true Inferred relationship Some 1
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Is a Therapy-related myelodysplastic syndrome (disorder) true Inferred relationship Some
Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Associated morphology Myeloid neoplasm post cytotoxic therapy (morphologic abnormality) true Inferred relationship Some 1

Inbound Relationships Type Active Source Characteristic Refinability Group
Therapy related acute myeloid leukaemia due to and following administration of antineoplastic agent Is a False Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Inferred relationship Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with radiation. The neoplastic cells typically harbor unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. Patients frequently present with multilineage dysplasia and cytopenias 5-10 years after exposure. Is a False Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Inferred relationship Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with a treatment of an unrelated neoplastic or autoimmune disease with cytotoxic agents, like cyclophosphamid, platins, melphalan and others. The neoplastic cells typically harbour unbalanced aberrations of chromosomes 5 and 7 (monosomy 5/del(5q) and monosomy 7/del(7q)) or a complex karyotype. It usually presents with multilineage dysplasia and cytopenias 5-10 years after exposure, with symptoms related to the degree of bone marrow failure and the corresponding cytopenia (fatigue, bleeding and bruising, recurrent infections, bone pain). Is a False Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Inferred relationship Some
A subgroup of therapy-related myeloid neoplasms (t-MN), associated with treatment of an unrelated neoplastic disease with cytotoxic agents, like etoposide, doxorubicin, daunorubicin and others. The neoplastic cells often show rearrangements involving the mixed lineage leukaemia gene at 11q23. This subgroup of t-MN is typically associated with overt leukaemia, without preceding myelodysplastic syndrome, developing 2-3 years after exposure, presenting with non-specific symptoms related to ineffective haematopoesis (fatigue, bleeding and bruising, recurrent infections, bone pain) and/or extramedullary site involvement. Is a False Therapy related acute myeloid leukemia and myelodysplastic syndrome (disorder) Inferred relationship Some

This concept is not in any reference sets

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