733487000: Dupilumab (substance)

SNOMED CT Concept\Substance\...

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Monoclonal antibody\Dupilumab

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Dupilumab

\Organic compound\Organic nitrogen compound\Amide and/or amide derivative (substance)\Substituted amide (substance)\Polypeptide\Protein\Antibody\Monoclonal antibody\Dupilumab

\Biological substance\Protein and/or protein derivative\Protein\Antibody\Monoclonal antibody\Dupilumab
\Biological substance\Immunologic substance\Antibody\Monoclonal antibody\Dupilumab
\Biological substance\Polypeptide\Protein\Antibody\Monoclonal antibody\Dupilumab

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jul 2017. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3499542013 Dupilumab en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

3499543015 Dupilumab (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

55941000195116 dupilumab it Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

807801000172115 dupilumab fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

71051000195116 Dupilumab de Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Dupilumab	Is a	Monoclonal antibody	true	Inferred relationship	Some
Dupilumab	Is a	Interleukin-4 receptor alpha antagonist	true	Inferred relationship	Some
Dupilumab	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Interleukin receptor antagonist (disposition)	false	Inferred relationship	Some
Dupilumab	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Interleukin 4 receptor alpha antagonist	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing dupilumab (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dupilumab	Inferred relationship	Some	1
Dupilumab-containing product in parenteral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dupilumab	Inferred relationship	Some	1
Dupilumab only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dupilumab	Inferred relationship	Some	1
Product containing only dupilumab in parenteral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Dupilumab	Inferred relationship	Some	1
Dupilumab 150 mg/mL solution for injection	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dupilumab	Inferred relationship	Some	1
Dupilumab 150 mg/mL solution for injection	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Dupilumab	Inferred relationship	Some	1
Product containing precisely dupilumab 175.439 milligram/1 milliliter conventional release solution for injection (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Dupilumab	Inferred relationship	Some	1
Product containing precisely dupilumab 175.439 milligram/1 milliliter conventional release solution for injection (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Dupilumab	Inferred relationship	Some	1

This concept is not in any reference sets