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734583009: Protein kinase inhibitor (disposition)

SNOMED CT Concept\Qualifier value (qualifier value)\Disposition\A substance that alters biochemical processes in a cell by decreasing or increasing the activity of an enzyme.\Compound or agent that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction US Library of Medicine MESH Descriptor data Accessed 20/01/2017\Transferase inhibitor (disposition)\Phosphotransferase inhibitor (disposition)\Protein kinase inhibitor (disposition)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3509211011 Protein kinase inhibitor (disposition) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3509212016 Protein kinase inhibitor en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Protein kinase inhibitor (disposition)	Is a	Phosphotransferase inhibitor (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Protein-tyrosine kinase inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
B-Raf inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Phosphoinositide 3 kinase inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Abemaciclib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Sirolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Protein kinase inhibitor	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Temsirolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Everolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Zotarolimus (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Nintedanib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Palbociclib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Ribociclib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Ribociclib succinate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Mitogen-activated protein kinase kinase inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Alpelisib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Avapritinib	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Nintedanib esilate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Trilaciclib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Trilaciclib dihydrochloride	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Fibroblast growth factor receptor inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Epidermal growth factor receptor inhibitor	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some
Non-specific serine threonine protein kinase inhibitor (disposition)	Is a	True	Protein kinase inhibitor (disposition)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3509211011	Protein kinase inhibitor (disposition)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3509212016	Protein kinase inhibitor	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core