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734620004: B-Raf inhibitor (disposition)

SNOMED CT Concept\Qualifier value (qualifier value)\Disposition\A substance that alters biochemical processes in a cell by decreasing or increasing the activity of an enzyme.\Compound or agent that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction US Library of Medicine MESH Descriptor data Accessed 20/01/2017\Transferase inhibitor (disposition)\Phosphotransferase inhibitor (disposition)\Protein kinase inhibitor (disposition)\B-Raf inhibitor (disposition)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3509626018 B-Raf inhibitor (disposition) en Fully specified name Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509627010 BRAF inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

3509628017 B-Raf inhibitor en Synonym (core metadata concept) Active Entire term case sensitive (core metadata concept) SNOMED CT core

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
B-Raf inhibitor (disposition)	Is a	Protein kinase inhibitor (disposition)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Vemurafenib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Dabrafenib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Dabrafenib mesilate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Substance with B-Raf inhibitor mechanism of action (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Trametinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Trametinib dimethyl sulfoxide (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some
Encorafenib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	True	B-Raf inhibitor (disposition)	Inferred relationship	Some

This concept is not in any reference sets

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Id	Description	Lang	Type	Status	Case?	Module
3509626018	B-Raf inhibitor (disposition)	en	Fully specified name	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3509627010	BRAF inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core
3509628017	B-Raf inhibitor	en	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT core