736632003: Neratinib (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Neratinib (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Neratinib (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Quinoline\Neratinib (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Amine and/or amine derivative\Quinoline\Neratinib (substance)

\Nitrile\Neratinib (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinoline\Neratinib (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Neratinib (substance)
\Organic compound\Organic nitrogen compound\Nitrile\Neratinib (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Neratinib (substance)	Is a	Quinoline	true	Inferred relationship	Some
Neratinib (substance)	Is a	Nitrile	true	Inferred relationship	Some
Neratinib (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some
Neratinib (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Neratinib (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Neratinib (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Neratinib maleate (substance)	Is a	False	Neratinib (substance)	Inferred relationship	Some
Product containing neratinib (medicinal product)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Some	1
Product containing neratinib in oral dose form (medicinal product form)	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Some	1
Neratinib maleate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	True	Neratinib (substance)	Inferred relationship	Some
Neratinib only product	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Some	1
Neratinib only product in oral dose form	The clinically relevant part or whole of the substance that is intended to have a therapeutic action on or within the body. It excludes esters, salts or other non-covalent derivatives (such as a complex, chelate etc.), but may include secondary modifications.	True	Neratinib (substance)	Inferred relationship	Some	1
Product containing precisely neratinib (as neratinib maleate) 40 milligram/1 each conventional release oral tablet (clinical drug)	This attribute represents an ingredient that is the part of the active ingredient that the strength of a given product is based upon.	True	Neratinib (substance)	Inferred relationship	Some	1

This concept is not in any reference sets

Back to Start

Id	Description	Lang	Type	Status	Case?	Module
3520526014	Neratinib (substance)	en	Fully specified name	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
3520527017	Neratinib	en	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT core
372211000195115	neratinib	it	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
1135601000241117	nératinib	fr	Synonym (core metadata concept)	Active	Entire term case insensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module
3340901001000111	Neratinib	de	Synonym (core metadata concept)	Active	Entire term case sensitive (core metadata concept)	SNOMED CT Switzerland NRC maintained Module