736633008: Neratinib maleate (substance)

SNOMED CT Concept\Substance\...

\Substance categorized by disposition\Substance with effector mechanism of action (substance)\Enzyme inhibitor\Transferase inhibitor\Phosphotransferase inhibitor\Protein kinase inhibitor\Protein-tyrosine kinase inhibitor\Neratinib maleate (substance)

\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Antineoplastic agent (substance)\Neratinib maleate (substance)
\A grouper concept for substances that are used in medicinal products for medical treatment, and also psychoactive substances that have few or no legitimate medical uses or that are not legally available to the person using them.\Quinoline\Neratinib maleate (substance)

\Substance categorised by structure\Chemical\Chemical categorized by structure (substance)\...

\Nitrogen and/or nitrogen compound (substance)\Nitrogen compound\Organic nitrogen compound\...

\Amine and/or amine derivative\Quinoline\Neratinib maleate (substance)

\Nitrile\Neratinib maleate (substance)

\Organic compound\Organic cyclic compound\Heterocyclic compound\Quinoline\Neratinib maleate (substance)
\Organic compound\Organic nitrogen compound\Amine and/or amine derivative\Quinoline\Neratinib maleate (substance)
\Organic compound\Organic nitrogen compound\Nitrile\Neratinib maleate (substance)

Status: current, Not sufficiently defined by necessary conditions definition status (core metadata concept). Date: 31-Jan 2018. Module: SNOMED CT core

Descriptions:

Id Description Lang Type Status Case? Module

3520528010 Neratinib maleate (substance) en Fully specified name Active Entire term case insensitive (core metadata concept) SNOMED CT core

3520529019 Neratinib maleate en Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT core

5496041000241112 maléate de nératinib fr Synonym (core metadata concept) Active Entire term case insensitive (core metadata concept) SNOMED CT Switzerland NRC maintained Module

Expanded Value Set

Outbound Relationships	Type	Target	Active	Characteristic	Refinability	Group	Values
Neratinib maleate (substance)	Is a	Neratinib (substance)	false	Inferred relationship	Some
Neratinib maleate (substance)	This attribute specifies the behavior that a substance will exhibit or participate in, given the appropriate context.	Protein-tyrosine kinase inhibitor (disposition)	true	Inferred relationship	Some
Neratinib maleate (substance)	Is a	Nitrile	true	Inferred relationship	Some
Neratinib maleate (substance)	Is a	Enzyme inhibitor	false	Inferred relationship	Some
Neratinib maleate (substance)	Is a	Quinoline	true	Inferred relationship	Some
Neratinib maleate (substance)	This attribute indicates that the concept is a structural modification of another concept, and that the substance's intrinsic physicochemical properties remain unchanged.	Neratinib (substance)	true	Inferred relationship	Some
Neratinib maleate (substance)	Is a	Protein-tyrosine kinase inhibitor	true	Inferred relationship	Some
Neratinib maleate (substance)	Is a	Antineoplastic agent (substance)	true	Inferred relationship	Some

Inbound Relationships	Type	Active	Source	Characteristic	Refinability	Group
Product containing precisely neratinib (as neratinib maleate) 40 milligram/1 each conventional release oral tablet (clinical drug)	The most specific description of a substance present in the manufactured dose form, before any dilution or transformation. It includes modifiers, such as salts, esters, polymers (e.g. pegylation), and/or solvates (including waters of hydration).	True	Neratinib maleate (substance)	Inferred relationship	Some	1

This concept is not in any reference sets